29/10/2025
What do your genetics tell us about your ability to process, metabolise, store, and absorb creatine? 🧬
We've officially launched our new 'Creatine Requirement' score in the Myoform app for existing users.
With all the rage about creatine in recent months, for good reason, we decided to jump into the science underpinning the genetics surrounding it.
Why it matters:
While creatine is found in red meat, fish, and poultry, genetic variations can affect your body's ability to synthesize, store, and utilize creatine efficiently. This depends heavily on several key genes - particularly GATM, SLC6A8, and CKM.
⚙️ GATM (glycine amidinotransferase) controls how efficiently your body synthesises creatine. Certain variants are linked to reduced endogenous production, meaning supplementation can have a dramatically higher payoff.
🚚 SLC6A8 regulates creatine transport into muscle cells - and some people have slower uptake, which affects strength and recovery gains from training.
💪 CKM (creatine kinase, muscle-type) affects how rapidly you turn over creatine phosphate during high-intensity effort - influencing short-burst power and fatigue tolerance.
Typical dietary recommendations are set around the 3-5g per day - sometimes varying with differing contexts (up to 10g+ for cognition) - but without proper education, how can you decide what is most appropriate?*
With Myoform's approach, we analyse these markers (and their interactions with s*x, training load, and diet) to calculate your optimal daily requirement - not just a flat “5g for everyone.”
If you want to find out how your own genetics may impact your performance, join our waitlist, today. 🧬
