08/08/2025
Intersting case !! Middle age female , presented with jaundice, gall stones , splenomegaly and anemia . She has no hitory of blood transfusion or hospital admission. Has family history of gall stones , and her daughter had anemia and splenomegaly . CBC hb: 8.1 TWBC 8.8 plt 247 MCV 75 , has high total bilirubin level mainly direct, viral screening is negative , blood film and full CBC below , what is the most likely diagnosis??