Agency for Care Effectiveness - ACE

Agency for Care Effectiveness - ACE ACE is the national health technology assessment (HTA) and clinical guidance agency in Singapore. What We Do


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Welcome to the official page of the Agency for Care Effectiveness (ACE). Established by the Ministry of Health, the Agency for Care Effectiveness (ACE) is the national Health Technology Assessment (HTA) and Clinical Guidance Agency in Singapore. We support providers, patients, and payers make better-informed decisions about patient care. We achieve this by conducting health technology assessments (HTAs), publishing healthcare guidances and providing education. HTA

Established by the Ministry of Health in 2015, we are the national HTA agency in Singapore. We conduct technical evaluations that inform funding decisions for health technologies, and drive their appropriate use by:

• Publishing technology guidances on the clinical effectiveness, safety, and cost-effectiveness of health technologies;
• Conducting value-based pricing negotiations with manufacturers to ensure that prices of patented health technologies are commensurate with the outcomes they deliver for patients and the Singapore health system;
• Tracking utilisation and outcomes related to funded health technologies to study the impact of funding decisions;
• Developing and implementing adoption strategies within public healthcare institutions to drive uptake of technology guidances. Clinical Guidance

We develop and publish clinical guidances that provide concise, evidence-based recommendations to inform specific areas of clinical practice. Healthcare Professional Education

We assist healthcare professionals to apply the best available evidence in their practice through collaborative continuing professional education. Healthcare Consumer Education

We provide information and tools for patients and caregivers to help them find out more about different medical conditions and treatment options, and to take part in shared decision-making with their clinicians about their healthcare needs. Find out more about our work at https://www.ace-hta.gov.sg/campaign/

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Social Media Terms of Use

We encourage all visitors on our page to start conversations and share with us your thoughts, suggestions, and comments, if any. While we welcome constructive discussions, and want everyone’s experience to be positive, please note that any offensive posts or comments will be removed, and users that repeatedly breach the terms of use may also be blocked from this page. As social media is not a platform for clinical advice – please get in touch with your pharmacist or doctor regarding medical queries. Out of respect for users of our page, ACE reserves the right to remove any comments or posts of the following nature:
- Abusive, vulgar, obscene, violent or defamatory language
- Hateful or discriminatory remarks towards any specific groups or individuals
- Advertising, promotion or endorsement of any products, services or brands
- Fraudulent, inaccurate, non-evidence based information, including spam
- Violation of any copyright, contains proprietary or personal information (email addresses, phone numbers, account numbers etc.)
- Any other comments or posts that breach Facebook’s Term of Service of Community Standards.

Chronic obstructive pulmonary disease (COPD) is a chronic lung disease that makes every breath harder, causing symptoms ...
19/11/2025

Chronic obstructive pulmonary disease (COPD) is a chronic lung disease that makes every breath harder, causing symptoms like persistent cough, wheezing and breathlessness. Over time, these symptoms can limit daily activities and may lead to hospitalisations.

The good news: COPD can be managed with the right inhalers and correct administration techniques, ensuring optimal delivery of medication to the lungs to control symptoms and improve quality of life.

Explore ACE’s patient resources for COPD here: go.gov.sg/acefb282, go.gov.sg/acefb283, go.gov.sg/acef284, go.gov.sg/acefb285

Managing diabetes isn’t just about controlling blood sugar levels— it’s about staying well every day with the right care...
14/11/2025

Managing diabetes isn’t just about controlling blood sugar levels— it’s about staying well every day with the right care, family support, and long-term follow-up.

From meal planning to medication and monitoring, having the right guidance makes all the difference in keeping diabetes under control and preventing complications.

This World Diabetes Day, explore ACE’s helpful diabetes resources for patients and families here: go.gov.sg/acefb279, go.gov.sg/acefb280, go.gov.sg/acefb281

Transthyretin amyloid cardiomyopathy (ATTR-CM) is a rare condition caused by abnormal protein build-up in the heart musc...
06/11/2025

Transthyretin amyloid cardiomyopathy (ATTR-CM) is a rare condition caused by abnormal protein build-up in the heart muscles. Over time, these protein deposits can cause the heart muscles to become thick and stiff, making it hard for the heart to pump blood effectively to the rest of the body. This may eventually lead to heart failure and repeated hospital stays.

When Mr S, a retiree, was diagnosed with ATTR-CM, he began treatment with tafamidis. But treatment costs were high – over $10,000 every month.

Following ACE’s health technology assessment and value-based pricing negotiations for tafamidis, the MOH Drug Advisory Committee (DAC) recommended this treatment for government subsidy. This has made tafamidis more affordable for Mr S, enabling him to access effective and value-based care.

Explore ACE’s patient resource on tafamidis for treating ATTR-CM: https://go.gov.sg/acefb286

04/11/2025

ACE conducts technical evaluations to assess the effectiveness, safety, and value of health technologies (such as drugs, vaccines, and medical devices) to inform the Ministry of Health (MOH) advisory committees when they make funding recommendations.

From October 2025 to the end of January 2026, patients, carers, and representatives from patient or voluntary organisations can submit applications to suggest which health technologies ACE should evaluate for funding.

Read our factsheet to learn more about how patients can be involved and contact your patient organisation for an application form: https://go.gov.sg/acefb278.

04/11/2025

Most people with osteoporosis don't realise they have it until they break a bone.

The good news is, it’s never too late to take action. Simple steps can help strengthen your bones and lower your risk of fractures.

Find out more about osteoporosis and the injectable treatments available for it in our factsheet:
go.gov.sg/acefb277

29/10/2025

Hepatocellular carcinoma (HCC) is the most common type of liver cancer. For patients who have unresectable HCC (when the cancer cannot be removed by surgery) but who still have adequate liver function, effective drug treatment options are available.

Learn more about the treatment options for unresectable hepatocellular carcinoma, in our factsheet: go.gov.sg/acefb276

✨ This Deepavali, we celebrate the triumph of light over darkness — and health, hope and togetherness for all.Wishing ev...
20/10/2025

✨ This Deepavali, we celebrate the triumph of light over darkness —
and health, hope and togetherness for all.

Wishing everyone a safe and joyous festival of lights.

🧠 This World Mental Health Day, let’s remember: depression is treatable.Selective serotonin reuptake inhibitors (SSRIs) ...
10/10/2025

🧠 This World Mental Health Day, let’s remember: depression is treatable.

Selective serotonin reuptake inhibitors (SSRIs) are among the most commonly prescribed medications for depression. They help restore balance to brain chemistry, improving mood, energy and quality of life.

Learn more about SSRIs here: go.gov.sg/acefb275

07/10/2025

🎉 This year, ACE turns 10! For the past decade, we’ve supported Singapore’s healthcare system with trusted guidances that empower healthcare providers and patients to make better healthcare decisions.
Now, as we look ahead, our team shares their hopes for what ACE can achieve in the next 10 years.

01/10/2025

ACE conducts technical evaluations to assess the effectiveness, safety, and value of health technologies — such as drugs, vaccines, and medical devices — to inform the Ministry of Health (MOH) advisory committees when they make funding recommendations.

From October 2025 until the end of January 2026, patients, carers, and representatives from patient or voluntary organisations can submit applications to suggest which health technologies ACE should evaluate for funding.

Read our factsheet to learn more about how patients can be involved and contact your patient organisation for an application form: go.gov.sg/acefb274

💨 On World Lung Day, let's highlight the importance of difference inhalers in asthma care.Without a preventer inhaler, s...
25/09/2025

💨 On World Lung Day, let's highlight the importance of difference inhalers in asthma care.

Without a preventer inhaler, symptoms can worsen — leading to serious breathing problems and even hospitalisation. Steroid inhalers are proven to reduce airway swelling, prevent flare-ups, and help people with asthma live well.

Learn more about steroid inhalers here: go.gov.sg/acefb269

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College Of Medicine Building, 16 College Road
Singapore
169854

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