Agency for Care Effectiveness - ACE

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Agency for Care Effectiveness - ACE

ACE is the national health technology assessment (HTA) and clinical guidance agency in Singapore. What We Do

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Welcome to the official page of the Agency for Care Effectiveness (ACE). Established by the Ministry of Health, the Agency for Care Effectiveness (ACE) is the national Health Technology Assessment (HTA) and Clinical Guidance Agency in Singapore. We support providers, patients, and payers make better-informed decisions about patient care. We achieve this by conducting health technology assessments (HTAs), publishing healthcare guidances and providing education. HTA

Established by the Ministry of Health in 2015, we are the national HTA agency in Singapore. We conduct technical evaluations that inform funding decisions for health technologies, and drive their appropriate use by:

• Publishing technology guidances on the clinical effectiveness, safety, and cost-effectiveness of health technologies;
• Conducting value-based pricing negotiations with manufacturers to ensure that prices of patented health technologies are commensurate with the outcomes they deliver for patients and the Singapore health system;
• Tracking utilisation and outcomes related to funded health technologies to study the impact of funding decisions;
• Developing and implementing adoption strategies within public healthcare institutions to drive uptake of technology guidances. Clinical Guidance

We develop and publish clinical guidances that provide concise, evidence-based recommendations to inform specific areas of clinical practice. Healthcare Professional Education

We assist healthcare professionals to apply the best available evidence in their practice through collaborative continuing professional education. Healthcare Consumer Education

We provide information and tools for patients and caregivers to help them find out more about different medical conditions and treatment options, and to take part in shared decision-making with their clinicians about their healthcare needs. Find out more about our work at https://www.ace-hta.gov.sg/campaign/

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Social Media Terms of Use

We encourage all visitors on our page to start conversations and share with us your thoughts, suggestions, and comments, if any. While we welcome constructive discussions, and want everyone’s experience to be positive, please note that any offensive posts or comments will be removed, and users that repeatedly breach the terms of use may also be blocked from this page. As social media is not a platform for clinical advice – please get in touch with your pharmacist or doctor regarding medical queries. Out of respect for users of our page, ACE reserves the right to remove any comments or posts of the following nature:
- Abusive, vulgar, obscene, violent or defamatory language
- Hateful or discriminatory remarks towards any specific groups or individuals
- Advertising, promotion or endorsement of any products, services or brands
- Fraudulent, inaccurate, non-evidence based information, including spam
- Violation of any copyright, contains proprietary or personal information (email addresses, phone numbers, account numbers etc.)
- Any other comments or posts that breach Facebook’s Term of Service of Community Standards.

21/03/2026

Selamat Hari Raya Aidilfitri! 🌙

As families and communities come together in celebration, ACE wishes all who celebrate a joyful and meaningful Hari Raya.
May this festive day bring peace, reflection, and renewed spirit as we continue working together towards better care for all.

19/03/2026

🏌Take your guidelines to the next level using ACE’s Guidelines for Guidelines (G4G)!

Clinical guidelines are key knowledge instruments that consolidate evidence and deliver systematic recommendations to enhance clinical decision-making processes. The methodological rigour directly impacts the effectiveness and clinical utility of the guidelines developed. The establishment of the nine G4G standards represents a comprehensive strategic initiative to elevate local guideline development capabilities, fostering the creation of scientifically robust, high-quality clinical guidance tailored to Singapore's unique healthcare environment. These standards provide a roadmap to advance procedural transparency and provide stakeholders with comprehensive understanding of the systematic approaches and recommendation development protocols through which evidence-based clinical guidelines should be formulated.

Read more at the ACE website: https://go.gov.sg/aceli415

🔜Watch this space for more on how to apply the G4G standards!

17/03/2026

We are pleased to share that ACE has contributed a chapter to the 2nd edition of the book “Patient Involvement in Health Technology Assessment”!

Chapter 23 – “Singapore: From Stakeholder Mapping to Continuously Improving Patient Participation in HTA” - showcases how ACE has been working with patients and carers since 2022 to strengthen their involvement in Singapore's healthcare decision-making processes.

The chapter reflects our commitment to ensuring that the voices of patients and carers are meaningfully considered in health technology assessments, helping funding recommendations better reflect what truly matters to those living with health conditions.

We thank our patient organisation partners for their collaboration and partnership in advancing this important work.

Click the link to read the full chapter: https://go.gov.sg/acefb302

03/03/2026

For over a decade, Mr Semba lived with severe mitral regurgitation, a heart condition that left him breathless and limited his daily activities.

As he was not suitable for open-heart surgery, treatment options were limited.

In this issue of ACE Insights, discover how ACE’s evidence-based evaluation informed the recommendation to subsidise transcatheter mitral valve leaflet repair (TMVLR) including MitraClip — improving access to a less invasive option for eligible patients and resulting in a better quality of life.

👉 Read the full story in the latest Issue: https://go.gov.sg/acefb298

17/02/2026

🍊 This Lunar New Year, we welcome the Year of the Horse — a symbol of strength, perseverance, and progress. As we come together to celebrate unity and resilience, we look forward to a year driven by renewed energy, hope, and shared purpose.

From all of us at ACE, we wish everyone a joyous Lunar New Year.

11/02/2026

We're excited to publish a new addition to our Voices to Impact flipbook! 📖

Our latest feature showcases how members of local patient groups partnered with ACE to co-develop factsheets on treatments for type 2 diabetes, turning medical jargon into accessible information and actionable steps.

Hear from Tiwari and Pratibha as they share their experience with the co-development process.

Click the link to read the full story: go.gov.sg/ace-voices-to-impact

23/01/2026

Immunotherapy is one of the treatment options for advanced non-small cell lung cancer (NSCLC) and several immunotherapy drugs are subsidised in Singapore for this condition.

Learn more about immunotherapy drugs for advanced NSCLC in our latest factsheet: go.gov.sg/acefb295

19/01/2026

ACE conducts technical evaluations to assess the effectiveness, safety, and value of health technologies (such as drugs, vaccines, and medical devices) to inform the Ministry of Health (MOH) advisory committees when they make funding recommendations. From October 2025 to the end of January 2026, patients, carers, and representatives from patient or voluntary organisations can submit applications to suggest which health technologies ACE should evaluate for funding. Topic suggestions close at the end of the month!

Read our factsheet to learn more about how patients can be involved and contact your patient organisation for an application form. go.gov.sg/aceli406

08/01/2026

Many people with chronic coronary heart disease (also known as chronic coronary syndrome) take antiplatelet medicines, such as aspirin, clopidogrel, or ticagrelor, to lower their risk of a heart attack.
Learn the common myths and facts about antiplatelet medicines in our patient education aid: go.gov.sg/acefb293

Singapore Heart Foundation

05/01/2026

We're excited to share a new addition to our Voices to Impact flipbook!

In this latest story, participants from six jurisdictions across the Asia-Pacific region, who attended the 12th HTAsiaLink 2025 Pre-Conference Patient Workshop, share their insights. The workshop was co-hosted by ACE and the Health Technology Assessment International (HTAi) Patient and Citizen Involvement in HTA Interest Group (PCIG).

Hear directly from the participants as they discuss:
• The impact of patient involvement in HTA
• Key enablers driving meaningful engagement
• Barriers to address in order to move forward

Click the link to read the full story on how the Asia-Pacific region is advancing patient-centred HTA decision-making: go.gov.sg/ace-voices-to-impact

01/01/2026

✨ As we welcome 2026, we look forward to new opportunities to advance Appropriate and Value-Driven Care for patients, families and the healthcare system.

From all of us at ACE, thank you for your continued trust and partnership. May the year ahead bring you health, happiness and meaningful progress.

03/12/2025

Many people with chronic coronary heart disease (also known as chronic coronary syndrome) take antiplatelet medicines such as aspirin, clopidogrel, or ticagrelor, to lower their risk of a heart attack.

Learn the common myths and facts about antiplatelet medicines in
our patient education aid: https://go.gov.sg/acefb290

Singapore Heart Foundation

Address

College Of Medicine Building, 16 College Road
Singapore
169854

Website

https://www.ace-hta.gov.sg/

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