Academic Medicine Research Institute - AMRI

Academic Medicine Research Institute - AMRI ​The Academic Medicine Research Institute (AMRI) is a one-stop research enabler that provides admi

Healthcare transformation isn’t just about new technology – it's about changing how we think. 💡 📊 Meet Assoc Prof  Lam, ...
30/03/2026

Healthcare transformation isn’t just about new technology – it's about changing how we think. 💡 📊

Meet Assoc Prof Lam, your not-so-usual scientist who proves that impactful healthcare doesn’t only happen at the bench or bedside – it happens in systems, models and data.

As a Deputy Director of the Health Services Research Centre (HSRC) and Head of Data Science at SingHealth Duke-NUS Academic Medical Centre, he combines a foundation in modelling and optimisation with data science and systems thinking to improve health services delivery at scale.

During COVID-19, his predictive modelling work across institutions including General Hospital demonstrated that healthcare capacity is not fixed – it is dynamically expandable.

Join us as we continue our 2026 RGR series with Advancing Immunotherapy for Chronic Hepatitis B: From Immune Monitoring ...
27/03/2026

Join us as we continue our 2026 RGR series with Advancing Immunotherapy for Chronic Hepatitis B: From Immune Monitoring to Novel Therapeutic Strategies!

Mark your calendars: 15 Apr 2026, 12.30pm - 1.30pm
Be part of the conversation: https://for.sg/rgr15apr

Swipe through for more and don’t miss the publication recommendations in the comments! 👉📑

Prof Antonio Bertoletti
Asst Prof Nina Le Bert
Dr Daniel Mahadzir

Duke-NUS Medical School
SingHealth
SingHealth Duke-NUS Global Health Institute

Can human organoids change the future of medicine? Singapore faces a growing disease burden driven by an ageing populati...
25/03/2026

Can human organoids change the future of medicine?

Singapore faces a growing disease burden driven by an ageing population. To address this, researchers from the SingHealth Duke-NUS Academic Centre (AMC) are rethinking how we study human disease and discover new treatments.

The Organoid Research & InnOvative Analytics Network (ORION) brings together five labs across National Heart Centre Singapore, National Neuroscience Institute, National Cancer Centre Singapore, Sengkang General Hospital, and Duke-NUS Medical School. Their expertise encompasses cardiac, brain, cancer, skeletal muscle, intestinal and airway organoids.

ORION is breaking new ground in human organoid research with a fully automated, high-throughput imaging and robotics platform that integrates organoid generation, maintenance, whole-mount immunostaining, tissue clearing, and high-content imaging. At the same time, the team is also building an organoid biorepository of healthy and diseased organoids that aims to accelerate drug discovery and personalised medicine.

Through this collaborative effort, ORION hopes to uncover new therapeutics and disease mechanisms, translating organoid into better health outcomes for all.

👉 Swipe for more!

Prof Derek Hausenloy, Asst Prof Chrishan Ramachandra, Prof Tan Eng King, Assoc Prof Shawn Je, Asst Prof Jason Chan, Prof Teh Bin Tean, Clin Assoc Prof Frederick Koh, Asst Prof Mart Lamers

23/03/2026

Exciting milestone: We have reached 4,000-followers on LinkedIn! ⭐

Thank you for being part of our growing and scientific community. Your support motivates us to continue sharing impactful stories, innovations, and insights from our researchers and partners.

Stay connected with us for more updates – and don’t forget to like, share and follow!



Visit Medicine Research Institute - AMRI at https://www.singhealthdukenus.com.sg/research

21/03/2026

Selamat Hari Raya Aidilfitri! 🌕

AMRI extends our warmest wishes to all our Muslim friends! May this festive season bring you joy, peace and cherished moments of togetherness with your loved ones.

Did you know: In Singapore, families often open their homes to relatives and friends during Hari Raya, sharing delicious dishes like ketupat, rendang and kuih, which is a beautiful expression of hospitality and unity 🩷



Visit Medicine Research Institute - AMRI at https://www.singhealthdukenus.com.sg/research

This World Oral Health Day, we spotlight D-IONIC, a non-invasive, painless dental anaesthesia delivery system developed ...
20/03/2026

This World Oral Health Day, we spotlight D-IONIC, a non-invasive, painless dental anaesthesia delivery system developed by Clin Assoc Prof Bee Tin Goh (Senior Consultant, Oral and Maxillofacial Surgery) and Dr Zayim Razina Seeni Syed (Senior Research Fellow) from National Dental Centre Singapore - NDCS.

As D-IONIC move towards clinical trials with support from SingHealth Intellectual Property (SHIP) and SingHealth Technology Incubator (SCOUT), it exemplifies how a strong translational ecosystem within the SingHealth Duke-NUS research community is essential in turning research into real-world impact for patients.

“By combining technological innovation with a strong foundation in intellectual property, we have successfully advanced D-IONIC, positioning it for clinical translation and market impact. The invaluable guidance from SHIP & SCOUT has empowered our team to adeptly navigate the complex IP landscape, ensuring robust patent protection. Their advice on technology development, commercialisation pathways and regulatory matters has been crucial in ensuring our innovation is both technically sound and commercially viable.” - Dr Zayim Razina Seeni Syed, Senior Research Fellow & Co-I

Catch the full interview here: https://for.sg/world-oral-health-day-2026

  Lipoprotein(a) – Lp(a) – levels have always been thought to be stable in adult life. Researchers from Changi General H...
19/03/2026

Lipoprotein(a) – Lp(a) – levels have always been thought to be stable in adult life.

Researchers from Changi General Hospital (CGH) discovered that there was significant variability in blood Lp(a) levels of patients with ischaemic heart disease when admitted to hospital for acute cardiac issues. At higher Troponin T level (marker of severity of myocardial injury), there was a higher proportion of patients with falsely lowered Lp(a) levels.

Their findings suggest that patients with elevated Troponin T and those with borderline Lp(a) levels would benefit from repeat Lp(a) testing outside their acute admissions to better assess their true Lp(a) levels for more accurate risk stratification.

Read more in Journal of Asian Pacific Society of Cardiology, JAPSC: https://bit.ly/46Jw8Rd

AMC researchers involved: Colin Yeo, Xuan Han Koh, Weien Chow, Aw Tar Choon, Wann Jia Loh



Visit Academic Medicine Research Institute - AMRI at https://www.singhealthdukenus.com.sg/research

Interested in learning how advances in immune monitoring are reshaping the fight against chronic Hepatitis B Virus (HBV)...
13/03/2026

Interested in learning how advances in immune monitoring are reshaping the fight against chronic Hepatitis B Virus (HBV)?

Join Prof Antonio Bertoletti, Asst Prof Nina Le Bert and Dr Daniel Mahadzir as they share insights into how emerging immunotherapeutic strategies are advancing immunotherapy and precision care for chronic hepatitis B.

Sign up now at https://for.sg/rgr15apr or scan the QR code in the image below!

Duke-NUS Medical School
SingHealth
SingHealth Duke-NUS Global Health Institute



Visit Academic Medicine Research Institute - AMRI at https://www.singhealthdukenus.com.sg/research

Over 70 attendees joined SingHealth Technology Incubator (SCOUT)’s webinar on Challenges and Opportunities of Health Inn...
12/03/2026

Over 70 attendees joined SingHealth Technology Incubator (SCOUT)’s webinar on Challenges and Opportunities of Health Innovation Entering China!

A big thank you to Mr John Cao, CEO of Plano, for sharing invaluable insights and sparking lively discussion from product-market fit to finding the right partner and Dr Danny Belkin, Director of SCOUT for moderating the session.

Expansion into a new market such as China can be challenging, but the session showed how a strategic and resourceful approach can increase the chances of success.

Thank you to everyone who tuned in! We look forward to seeing you at the next SCOUT webinar!

SingHealth

  An ageing population significantly impacts the global burden of oral diseases. Given that oral diseases are chronic, p...
12/03/2026

An ageing population significantly impacts the global burden of oral diseases. Given that oral diseases are chronic, progressive, and cumulative, older adults are likely to experience an accumulation of these conditions, which can adversely affect their quality of life

Researchers from National Dental Centre Singapore - NDCS and Duke-NUS Medical School conducted a study to review the association between oral health conditions and older adults' general health-related quality-of-life (HRQoL).

Their results showed fewer teeth and chewing difficulty negatively impacted HRQoL, with chewing difficulty emerging as a novel finding in systematic reviews.

Read more in Journal of Dentistry, Science Direct: https://bit.ly/3INxgtV

AMC researchers involved: Huihua Li, Christina P C Sim, Karen G Peres

Collaborators: Daniela de Rossi Figueiredo (University of South Santa Catarina)



Visit Academic Medicine Research Institute - AMRI at https://www.singhealthdukenus.com.sg/research

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