Chi Prelude TCM Wellness

02/07/2024

20 Years of Big data: Does Multivitamins works for healthy people?
20 年的大数据 ： 复合维生素对我们有用吗？

最近发表在JAMA的一项研究确定了美国成年人定期补充多种维生素(MV)与死亡风险之间的关系。

A recent study published in JAMA Network Open determined the relationship between regular multivitamin (MV) supplementation and mortality risk among United States adults.

2022年美国预防服务工作队(USPSTF)审查了随机对照试验中关于多种维生素使用和死亡风险的数据，并得出结论认为，由于随访时间短，没有足够的证据来确定风险-效益比。

The 2022 United States Preventive Services Task Force (USPSTF) examined data on multivitamin use and death risk from randomized controlled trials and concluded that owing to short follow-up duration, there is inadequate evidence to determine risk-benefit ratios.

观察性研究提供了相互矛盾的结果，多种维生素含量的差异或混杂因素可能解释了它们不同的结果。

Observational studies provide contradictory results, and differences in multivitamin content or confounding factors may explain their varied outcomes.

在目前的研究中，研究人员研究了定期服用多种维生素是否能降低成年人的死亡风险。

In the present study, researchers investigated whether regular multivitamin usage can lower death risk in the adult US population.

该研究纳入了参加前列腺癌、肺癌、结直肠癌和卵巢癌筛查(PLCO, 42,732人)试验的无慢性病史和癌症史的成年人;农业健康研究(AHS, 19660人)或美国国立卫生研究院AARP饮食与健康研究(NIH-AARP, 327732人)。

The study included adults with no previous histories of chronic medical conditions and cancer who enrolled in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening (PLCO, 42,732 individuals) trial; the Agricultural Health Study (AHS, 19,660 individuals) or the National Institutes of Health-AARP Diet and Health Study (NIH-AARP, 327,732 individuals).

参与者完成了基线调查问卷，以提供多种维生素的服用数据。

Participants completed baseline questionnaires to provide multivitamin usage data.

时变分析分别纳入了AHS、PLCO和NIH-AARP研究开始后5年、3年和9年的随访饮食问卷数据。

The time-varying analyses incorporated follow-up dietary questionnaire data five years, three years, and nine years after initiating the AHS, PLCO, and NIH-AARP studies, respectively.

该研究包括390,124人:327,732人来自NIH-AARP, 42,732人来自PLCO, 19,660人来自AHS。

The study included 390,124 individuals: 327,732 from NIH-AARP, 42,732 from PLCO, and 19,660 from AHS.

参与者的中位年龄为62岁，55%为男性。

The median participant age was 62 years, and 55% were male.

研究人员在随访期间共发现164,762人死亡;在164,762例死亡中，49,836例死于癌症，35,060例死于心血管疾病，9,275例死于脑血管疾病。

In total, the researchers noted 164,762 demises in the follow-up period; Of the 164,762 deaths, 49,836 resulted from cancer, 35,060 from cardiovascular diseases, and 9,275 from cerebrovascular diseases.

他们估计了随访前半期和后半期(即随访期1 [FP1]和随访期2 [FP2])的相对风险，

they estimated relative risks in the first and second halves of follow-up (ie, follow-up period 1 [FP1] and follow-up period 2 [FP2],

在前半期中，55岁以下的个体，定期服用多种维生素者任何原因死亡的风险更高(HR, 1.2)。

In the initial follow-up analysis (FP1), HR values for regular multivitamin usage and any-cause death were higher for individuals aged below 55 years (HR, 1.2).

荟萃分析纳入了来自所有队列的随时间变化的估计，表明与不使用相比，定期使用多种维生素与前半期的任何原因死亡风险增加4.0%相关，而与后半期无关。

The meta-analysis, incorporating time-varying estimates from all cohorts, showed that regular multivitamin usage, compared to non-usage, was related to a 4.0% higher risk of any-cause death in FP1 but not in FP2.

研究结果并没有提供经常服用多种维生素的人寿命延长的证据。

The study findings do not provide evidence of increased longevity among regular multivitamin users.

然而，不能排除定期服用复合维生素对其他与衰老相关的健康结果的可能影响。

However, one cannot rule out the possible effects of regular multivitamin usage on other aging-related health outcomes.

Journal references:

Loftfield E, O’Connell CP, Abnet CC, et al., Multivitamin Use and Mortality Risk in 3 Prospective US Cohorts. JAMA Netw Open. 2024;7(6):e2418729.

DOI: 10.1001/jamanetworkopen.2024.18729 https://jama.jamanetwork.com/article.aspx?doi=10.1001/jamanetworkopen.2024.18729

04/02/2024

祝大家立春大吉

27/11/2023

Interesting trend happening in US

https://www.webmd.com/children/news/20231027/more-parents-turning-to-acupuncture-for-kids-pain-anxiety

24/10/2023

Stroke may strike during sleep and why

When stroke strikes, it is often painless, so if it happens while someone is asleep it usually does not wake them up. The person only realises that something is wrong when they experience the symptoms of stroke when getting up, such as weakness on one side of the body as they get out of bed, noticing one side of their face drooping while looking in the mirror, or speech difficulties when they talk to someone

Fast emergency care increases the chance of a good recovery, as some treatments need to be given within a certain amount of time from when stroke symptoms first start.

When the stroke happens during sleep, there are no witnesses to advise medical staff on when symptoms started, but brain scans can help doctors determine how long ago the stroke happened and sometimes treatment can still be given to dissolve or remove the blood clot that caused the stroke.

Patients with wake-up stroke who receive such treatment have less long-term disability compared to those who are not able to have the treatment because they arrive at hospital too late. That is why it is so important to seek emergency care immediately when symptoms of stroke are first seen – do not go back to bed to try to sleep off the symptoms!

A stroke can happen to anyone at any time. We spend about 6 to 8 hours asleep every night – this is a significant proportion of our time and explains why a stroke sometimes occurs during sleep.

In addition, obstructive sleep apnoea (OSA) can increase stroke risk during sleep. OSA causes breathing to be reduced or stop temporarily. This results in less oxygen in the blood, increasing the possibility of stroke. Snoring and daytime sleepiness are common signs of OSA

OSA can also trigger an irregular heart rhythm pattern called atrial fibrillation which is a risk factor for stroke. Atrial fibrillation causes blood to pool in the heart chambers making it easier for blood clots to form.

Both atrial fibrillation and OSA can be treated with medication, medical devices and / or lifestyle changes, lowering your risk of stroke and other health complications.

06/06/2023

今天是二十四節氣中的「 #芒種」

芒種是農歷二十四節氣中的第九個節氣，也是夏季的第三個節氣，表示仲夏時節的正式開始。

芒種，「芒」指的是一些有芒的作物，如稻、黍、稷等；而「種」分別代表種子的「種」和播種的「種」。「芒種」之名含義就是有芒之穀類作物可種，過了即失效，因此民俗說「芒種不種，再種無用」，也表現了芒種節氣是種植農作物時機的分界點。

俗話說：「芒種夏至天，走路要人牽；牽的要人拉，拉的要人推」，表示這個時節容易疲勞的狀態，且容易引起皮膚和腸胃問題，因此在這個時節養生主要清熱化濕、養心。

飲食上可補充健脾的紅薯、滋陰潤燥的菠菜、荔枝、白木耳、蘆薈、秋葵、蓮藕、青梅、黃瓜、檸檬、蘿蔔、茄子、西瓜、苦瓜、番茄，夏天更合適吃些含鉀較多的食物，如玉米、毛豆、大豆、香蕉、香菜、芹菜等。

祝福大家在芒種時期，即使忙仍心不茫，記得多喝水喔！

#24節氣

30/05/2023

Finally completed this training. Learnt lots of evidence based medical knowledge - medical , lifestyle to stress management. This will complement my existing TCM knowledge.

18/05/2023

大家注意哦， 希望能帮助您家的老人：

癸卯贺新春，玉兔迎丰年，
太乙徙中宫，八风今日观，
年长少走动，居家避三虚，
内经藏大法，四月初一见。

（根据内经九宫八风哲理，癸卯年正月初一为太乙五步迁徙中宫日，又逢今日月亏，故老年人应居家避贼风，今年尚有四月初一日需避三虚（阳历5月19日），仅供参考）

14/05/2023

To all mummies, happy mother's day. Thank you for making the differences to future mankind :)

18/04/2023

我很少分享YouTube 视频。

“大医精诚” 是我们当医师的主要核心。 不分贵贱种族，宗教，好坏， 在我面前就是患者， 我只负责救或治人 和他的心。 以百姓为出发点， 但要维持自己的生活， 目前在新加坡当医师，真的有一定的难度。我还是秉持这个理念， 尽量为老百姓服务。

永远感谢我恩师提点仁心仁术。

有时间， 慢慢看。

《典籍里的中国》聚焦中华优秀文化典籍，从中甄选最值得讲述的优秀传统文化作品，以“文化节目+戏剧+影视化”的方式，讲述典籍的成书、核心思想以及流转中的闪亮故事，让书写在典籍里的文字“活”起来，展现典籍里蕴....

07/04/2023

TCM treat the mind using heart, spleen and kidneys functions. Want to make a guess which which organ is related to which "Mind"?

06/04/2023

[Health tip] How to correctly use a pillow when you sleep?

30/03/2023

How does acupuncture work? Watch a 3-minute video explaining how acupuncture works from a scientific perspective. For a full-length article, visit: https://c...