26/07/2022
Modern lifestyle (air pollution, dietary changes, use of antibiotics, etc.) appears to decrease a desirable exposure to microbial antigens, opportunistic pathogens and nonpathogens. This can lead to an inappropriate stimulus of macrophages and dendritic cells and an increase the severity and prevalence of chronic diseases, like allergies and autoimmune diseases in pets and humankind, due an incorrect modulation of the immune system [22]. Recently, evidence has indicated that obesity and type 2 diabetes are characterized by chronic inflammatory
processes. In adipose tissues, especially visceral tissues, this type of inflammation contributes to the onset of metabolic disturbances and increased insulin resistance [23].
In this context, purified yeast β-glucan could be a sought after option to recover the appropriate stimulus of macrophages and dendritic cells. With over 30,000 published studies, it is the most studied immunomodulator. Beneficial effects of β-glucans on animal and human health have been widely described in the literature and include immunomodulatory, prebiotic, adsorptive to zearalenone, anti-infective, anti-inflammatory, antitumor, antidiabetic, antimutagenic, anti-allergic, anti-enteritis, regenerative, anti-thrombogenic, anticoagulant, antioxidant, lipid-lowering, and radioprotective [15-17, 24-28].
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Unraveling yeast and yeast derivatives: immunological effects on July 21, 2022 Get link Facebook Twitter Pinterest Email Other Apps Authors:Carlos Alberto Ferreira de OliveiraKemin IndustriesVaclav VetvickaUniversity of LouisvilleModern lifestyle (air pollution, dietary changes, use of antibioti...