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The Regeneration Center

Stem Cell Regeneration Center is dedicated to providing regenerative stem cell treatments in Thailand

Stem Cell Regeneration Center of Thailand "SCT" is dedicated to providing regenerative stem cell treatments for many degenerative conditions.

01/02/2026

Gut Microbes Steer Cancer Growth and Immunity via Asparagine Metabolism

New findings point to a link between the gut microbiome and how cancer grows and how the immune system fights it. Bacteria in the gut can influence tumor behavior by how they process asparagine, an amino acid that many cancer cells rely on. By altering asparagine metabolism, gut microbes may tip the balance between tumor growth and immune attack. That connection opens possibilities for therapies that target gut microbes or diet to modulate asparagine levels, offering a potential complement to traditional cancer treatments. More research will determine how to translate this into practical strategies for patients.

31/01/2026

Repetitive negative thinking linked to cognitive decline in older adults

Repetitive negative thinking (RNT) – a pattern of persistent worry common in depression and anxiety – appears to be tied to slower cognitive function in people 60 and older. In a cross‑sectional analysis of 424 community‑dwelling seniors, researchers measured RNT with the Perseverative Thinking Questionnaire and assessed cognitive function with the Montreal Cognitive Assessment. After accounting for other factors, those with higher RNT scores showed lower cognitive scores. In particular, participants in the upper two quartiles of RNT had modest but consistent declines in MoCA results compared with the lowest quartile. The effect was more pronounced among adults aged 60 to 79 and among individuals with junior high school education or higher, suggesting the relationship may vary with age and education. The findings point to a potential link between a common thinking pattern and cognitive aging, highlighting the importance of addressing RNT as part of strategies to preserve mental sharpness in later life. More multi‑center, long‑term efforts are needed to uncover the mechanisms behind this link.

30/01/2026

Impulse Oscillometry in Lung Testing Reveals Small Airway Health

Impulse oscillometry system (IOS) is a test that measures lung mechanics during quiet breathing, offering a complementary view to traditional lung function tests. Since 2010, research shows IOS resistance measures (R5-20) align with obstructive problems such as COPD and asthma, while reactance-related metrics reflect restrictive changes and diffusion limits, especially in interstitial lung disease. Across conditions, R5-20 and resonant frequency are particularly sensitive to small airway dysfunction. Clinically, IOS helps gauge bronchodilator response, monitor asthma control, detect small airway issues even when spirometry is normal, and track exposure-related airway effects. Artificial intelligence models using multi-parameter IOS data show potential for screening and classifying lung disease. Overall, IOS adds valuable physiological and clinical information beyond standard tests, but large, multicenter studies and standardization are needed before widespread clinical use.

29/01/2026

Leigh syndrome reveals early brain development glitches

Leigh syndrome, a genetic mitochondrial disorder, shows brain damage and movement problems in children. New findings with Complex I dysfunction reveal that during infancy, neural and glial precursor cells (the cells that form neurons and supporting brain tissue) struggle to proliferate and mature. The study tracks development in two key brain regions, the subventricular zone and the corpus callosum, and finds problems emerge after birth but before classic neurodegeneration. Slowed neural stem cell growth, fewer neurons and oligodendrocytes (the cells that make myelin, which insulates nerve fibers), and changes in cell lineages point to a disrupted development process rather than only later degeneration. This suggests that LS may have neurodevelopmental signatures that appear well before typical symptoms and brain lesions, which could help explain early behavioral or developmental delays observed in patients and highlight a potential window for early diagnosis or intervention before irreversible damage occurs.

28/01/2026

WHO Urges Stronger Taxes on Sugary Drinks and Alcohol

WHO recommends strengthening taxes on sugary drinks and alcoholic beverages. Health taxes reduce harmful consumption and unlock funds for vital health services. Across regions, alcohol tax shares remain low with medians of 14% for beer and 22.5% for spirits. Sugary drink taxes are weak and poorly targeted, with the median tax accounting for about 2% of the price of a common sugary soda and often applying only to a subset of beverages. Inflation and income growth outpace tax changes, allowing health-harming products to become more affordable over time. At least 116 countries tax sugary drinks, but many high-sugar products such as 100% fruit juices, sweetened milk drinks, and ready-to-drink coffees and teas escape taxation. At least 167 countries levy taxes on alcoholic beverages, while 12 ban alcohol entirely; wine remains untaxed in at least 25 countries. The 3 by 35 initiative aims to raise the real prices of to***co, alcohol and sugary drinks by 2035, making them less affordable and protecting health.

27/01/2026

Biomarkers, AI and Trial Design Shape Outcomes

Biomarkers predict response to Palbociclib-Anastrozole therapy, enabling targeted patient selection. Machine Learning advances predictions in neuroblastoma metabolism, guiding risk stratification and treatment planning. Endoscopic scores predict Crohn’s disease outcomes post-surgery, informing postoperative management strategies. acupuncture design impacts migraine trial outcomes, highlighting the need for rigorous controls.

26/01/2026

Brain-Derived Neurotrophic Factor: A Key Molecule for Memory in the Healthy and the Pathological Brain

The expression of BDNF is highly regulated, and can lead to great variability in BDNF levels in healthy subjects. Changes in BDNF expression are associated with both normal and pathological aging and also psychiatric disease, in particular in structures important for memory processes such as the hippocampus and parahippocampal expression of BDNF is regulated during transcription and translation, and also by post-translational modifications. The presence of a complex multi-level regulation demonstrates the importance and diversity of BDNF functions. Reduced levels of BDNF have been reported not only under normal aging conditions but also in pathological conditions including Huntington (HT), Alzheimer’s disease (AD), and Parkinson’s disease. However, the profile of cognitive deficits greatly differs between these pathologies according to the brain regions affected by degeneration.

24/01/2026

Stem Cell Therapy for Spinal Cord Injury

Stem cell therapy targets regeneration of axons between brain and body that have been severely limited or non-existent after spinal cord injury. Stem cell transplants for spinal cord injury help patients eliminate pain, regain bladder and bowel function, and recover lost sensations. Stem cell therapy regenerates visceral motor neurons and adult astrocytes while minimizing cramps or depression from injury. Conventional treatments do not address regeneration and focus on pain management, rehabilitation, and reduction of secondary damage. Cell-based treatments take a proactive approach, emphasizing regeneration through targeted therapy. Spinal cord injuries are classified as complete or incomplete; complete injuries indicate total loss of sensory or motor function below the injury, while incomplete injuries retain some communication. Spinal injuries occur most often in the cervical and thoracic regions and affect young adults and men. Regenerative therapies aim to improve long-term outcomes by addressing chronic conditions alongside pain management and rehabilitation. Regaining function depends on managing systemic failures and chronic conditions through targeted regeneration therapy.

22/01/2026

Diabetes Complications: Mechanisms, Prevention, and Treatments

Spatial multiomics and single-cell transcriptomics reveal molecular heterogeneity and inter-organ crosstalk in diabetes. Digital diabetes prevention programs demonstrate effectiveness in high-risk populations by supporting remote lifestyle changes, reducing hemoglobin A1c, and delaying type 2 diabetes. Sodium-glucose cotransporter 2 inhibitors, glucagon-like peptide-1 receptor agonists, and nonsteroidal mineralocorticoid receptor antagonists reshape the therapeutic landscape for diabetic complications, with combination therapies offering additive or synergistic effects. Mesenchymal stem cells and exosomes, gut microbiota modulation, bioactive compounds from traditional medicine, and disease management systems offer promising approaches to correct molecular dysfunctions. Regenerative therapies integration into clinical workflows remain critical bottlenecks, with long-term safety and limited data diversity plus low model interpretability hindering generalizability and clinical trust.

21/01/2026

Designing Custom "Molecular Scissors" to Target Alzheimer's Disease

Scientists have developed a new method to create custom-made enzymes that act like "molecular scissors" to cut specific proteins. Using a computer model called Proteus2, they designed specialized enzymes (metalloproteases) specifically programmed to target and break down Amyloid-beta, a protein known for forming harmful clumps in the brains of Alzheimer’s patients.

20/01/2026

Regenerative therapies reduce reliance on organ transplantations by harnessing stem cells' self-renewal and differentiation into multiple lineages. Regenerative engineering of organs or tissues develops biological replacements for dysfunctional organs or injured tissues. Engineering organs outside the body faces obstacles from limited human cell availability, lack of a matching matrix architecture and composition, and maintenance of organ viability without blood supply. Bioreactors provide defined nutrient and growth factor media to sustain engineered organ viability. Engineered extracellular matrices and stem cells contribute to organ regeneration outside the body. Clinically, various adult stem cell therapies are readily under practice. Stem cells are undifferentiated cells with self-renewal that differentiate into cells with specialized functions. Stem cells’ pluripotency, differentiation, and self-regeneration support their use against traumatic brain injury, stroke, Alzheimer’s, Parkinson’s, spinal cord injury, deafness, blindness, wound healing, myocardial infarction, arthritis, muscular dystrophy, and diabetes. Organ transplantation remains clinically important for kidney or liver failure. However, the main obstacle in the organ transplantation program is the intense shortage of donor organs.

https://pmc.ncbi.nlm.nih.gov/articles/PMC9973391/

19/01/2026

Cholesin is a cholesterol-induced gut hormone that inhibits hepatic cholesterol synthesis. Cholesin is secreted from the intestine in response to cholesterol absorption and binds to GPR146. Cholesin inhibits PKA-ERK1/2 signaling via binding to GPR146, thereby suppressing SREBP2-controlled cholesterol synthesis in the liver. Cholesin reduces circulating cholesterol levels in both humans and mice. The Cholesin-GPR146 axis mediates the inhibitory effect of intestinal cholesterol absorption on hepatic cholesterol synthesis, offering a promising avenue to combat hypercholesterolemia and atherosclerosis.

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725 Sukhumvit Road
Bangkok
10110

เวลาทำการ

จันทร์	09:00 - 17:00
อังคาร	09:00 - 17:00
พุธ	09:00 - 17:00
พฤหัสบดี	09:00 - 17:00
ศุกร์	09:00 - 17:00

เบอร์โทรศัพท์

+66808069391

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https://stemcellthailand.org/

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Regenerative Non-Surgical Medical Solutions

Stem Cell Regeneration Center of Thailand "SCT" is dedicated to providing regenerative stem cell treatments for many degenerative conditions. Our specialty as a biotech company that manufactures best-in-class, allogeneic, adult stem cells and stem cell-derived factors.