07/11/2025
📌 Overcoming immune suppression in metastatic cancers is one of the biggest challenges in cancer treatment, severely limiting the efficacy of current immunotherapies.
📌 New research is focused on the STING (Stimulator of Interferon Genes) pathway, a key cellular mechanism that, when activated, triggers a potent anti-tumor immune response.
📌 However, STING activators must be delivered precisely to the metastatic site without causing severe systemic toxicity. This is where Nanoparticle-Based Delivery Systems come into play.
📌 This review details how nanoparticles safely and effectively carry STING agonists to target cells, essentially "switching on" the immune system for a sustained attack against the cancer.
📌 The study suggests that these next-generation STING-activating strategies hold significant promise for developing highly effective and less toxic treatments for metastatic cancer patients.
To read more, please check TMSJ's latest issue from our website, turkmedstudj.com
