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24/04/2026

Testicular cancer is the most common solid tumor in men aged 15–44. Most cases are germ cell tumors,accounting for 90–95% of all testicular cancers.The average age at diagnosis is 33 years.

Established risk factors include a history of undescended te**is (cryptorchidism), family history, genetic susceptibility, andearly-life environmental exposures, all of which contribute to increased susceptibility to germ cell tumors.

Early signs of testicular cancer typically include a lump, swelling, or change in size of a testicle, which may be painless oraccompanied by discomfort or a dull ache in the lower abdomen or groin.

Prognosis is generally excellent. Localized disease has a five-year survival above 99%, and even metastatic germ celltumors achieve high cure rates with proper management.

Promoting awareness and encouraging open discussions may help support early detection and timely care.

‘’The information shared on this page is not intended to replace the advice of a doctor or pharmacist. For more detailed information, please consult your doctor or pharmacist.’’

22/04/2026

Primary Immunodeficiencies are often described as “rare.”

Yet in clinical practice, the real challenge is not rarity alone, but recognition.

Delayed diagnoses, heterogeneous presentations, and fragmented care pathways continue to shape patient outcomes.

Initiatives like World PI Week remind us that awareness is not the endpoint.

It is the starting point for earlier suspicion, more accurate diagnosis, and equitable access to care.

Because in Primary Immunodeficiencies, what remains unseen often defines the patient journey.

21/04/2026

We were pleased to welcome our CEO İsmet İnce to Inpharmus Türkiye for our second Country Visit meeting of 2026.

As part of our MERAT strategy, our operations in Türkiye continue to grow in both scale and scope. The energy of our team and their strong ex*****on mindset clearly reflect our Speed & Star culture in action.

We are moving with focus, accelerating with purpose, and building sustainable impact throughout our unicorn journey.

17/04/2026

On World Haemophilia Day, we recognise the clinical complexity of hereditary bleeding disorders and the ongoing gaps in awareness, diagnosis, and access to care.

As research and innovative therapies continue to evolve, ensuring early recognition and equitable care remains essential for improving outcomes in haemophilia.

13/04/2026

Pediatric oncology is not a smaller version of adult oncology. The biology differs, theburden is shaped by early mortality, and outcomes depend heavily on timely diagnosis andaccess to specialized care.

“The information shared on this page is not intended to replace the advice of a doctor or pharmacist. For more detailed information, please consult your doctor or pharmacist.’’

10/04/2026

Cytokine storm is a hyperinflammatory syndrome characterized by excessive cytokine release and systemicimmune activation that may progress to multiorgan dysfunction.

Clinically, it is associated with high fever, hypotension, hypoxemia, and laboratory abnormalities including elevated C-reactive protein and ferritin, cytopenias, hypertriglyceridemia, increased D-dimer levels, and markedly elevatedcirculating cytokines such as interleukin-6, interferon-γ–related chemokines, interleukin-10, and soluble interleukin-2 receptor alpha.

In infection-associated hyperinflammatory states, endothelial dysfunction, increased vascular permeability, microvascularthrombosis, and coagulopathy have been described as contributing mechanisms in severe disease.

Cytokine storm can occur in diverse clinical contexts, including severe infections and immune-based therapies such as CAR-T cell therapy, where rapid immune cell activation is associated with high systemic cytokine levels.

‘’The information shared on this page is not intended to replace the advice of a doctor or pharmacist. For more detailed information, please consult your doctor or pharmacist.’’

07/04/2026

World Health Day reminds us that global health is defined not only by treatment capacity, but by awareness, equity,and early recognition.

Today, more than half of the world’s population still lacks full access to essential health services, according to the World HealthOrganization (WHO). (https://www.emro.who.int/world-health-days/2024/key-messages.html) This gap becomes even moreprofound for individuals living with rare neurologic, metabolic, autoinflammatory, and immune disorders, where clinicalcomplexity and overlapping symptoms often contribute to long diagnostic delays.

Strengthening health systems therefore begins with strengthening scientific understanding. Awareness is not an abstractconcept; it is a measurable determinant of health outcomes. Early recognition, informed primary care, and continuous medicaleducation collectively shape a more resilient and equitable care pathway.

On World Health Day, we highlight a simple truth:

Health improves when understanding deepens, especially for conditions that remain hardest to recognize.

03/04/2026

On March 30 and 31, the EXCOM Offsite was held at NG Sapanca. Over two days, our leadership team, together with our CEO İsmet İnce, focused on strengthening self-awareness, understanding individual and collective strengths, and reflecting on the behavioural patterns that influence how we grow as an organization.

The program opened with an interactive workshop on saboteurs led by Manfred Mahrle, exploring how certain thinking patterns can quietly work against us even when they originate from our strongest capabilities. In the afternoon, the team engaged in a strengths-focused session featuring a keynote, matrix exercises, and individual reflection. These conversations offered valuable insights into what we are genuinely good at and what may hinder us during periods of rapid growth.

As Inpharmus continues to expand in oncology and rare diseases, understanding both our internal drivers and potential barriers remains essential. This offsite created meaningful space for alignment, clarity, and readiness for the opportunities ahead.

01/04/2026

As we mark National Cancer Week (April 1–7), we recognize the growing globalimpact of cancer and the importance of strengthening prevention, early diagnosis, and access toinnovative care.

With nearly 20 million new cases each year, the need for collaborative, science-driven solutionshas never been greater. Continued progress in research, screening, and multidisciplinaryoncology care is key to improving long-term outcomes for patients worldwide.

This week, we stand with everyone affected by cancer and reaffirm our commitment toadvancing awareness, scientific innovation, and quality of care.

27/03/2026

Advancing the future of healthcare requires scientific depth supported by organizational systems that can adapt, scale, and sustain long-term impact.

On March 25 and 26, our CEO, Excom members and the Inpharmus operations team completed the EFQM Foundation Training delivered by the Turkish Quality Association (). Through the EFQM framework, we are enhancing our capabilities in agile decision-making, process maturity, and performance evaluation.

This structured approach enables Inpharmus to anticipate change, adapt efficiently, and maintain operational excellence across complex therapeutic areas and geographies. With each step, we reinforce our role as a science-driven and future-ready organization.

23/03/2026

Immune balance plays a critical role in maintaining overall health.

When the system becomes misdirected or overstimulated, the body can experience significantphysiological strain from autoimmune activity to acute hypersensitivity reactions.

Emerging research highlights gene-level signatures that may reveal early signs of immunedysregulation even before symptoms develop.

A reminder of how precise and dynamic our immune system truly is.

‘’The information shared on this page is not intended to replace the advice of a doctor or pharmacist. For more information, consult your doctor or pharmacist.’’

16/03/2026

Recent 2024–2026 research confirms that when our senses fade, our cognitive health pays the price.

Your Brain Pays the Price: Struggling to hear or see forces the brain to divert energy from memory to basic perception, leading tomental fatigue and decline.

Dual Sensory Loss: A 50% Higher Dementia Risk: Experiencing both hearing and vision loss (Dual Sensory Impairment) increases your dementia risk by over 50%.

When the Brain Quite Literally Shrinks: Without sensory stimulation, the areas of the brain responsible for processing sound and sight can physically shrink over time.

Early detection matters. Annual screenings are one of the simplest, most impactful ways to protect long-term cognitive health.

Address

Esentepe, Büyükdere Caddesi Kanyon Ofis Bloğu No: 185 Kat: 14, 34394 Levent/Şişli/Şişli/Istanbul
Istanbul
34000

Website

https://www.inpharmus.com/

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Op.Dr.Sezgin DURSUN- DOKTOR
Icerenkoy Mah. Kayisdagi Caddesi Tabiat sokak

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