05/03/2023
Traditionally, the most effective medications for the treatment of fibromyalgia have been the tricyclic antidepressants, medications often used in treating depression. Tricyclic antidepressants appear to reduce fatigue, relieve muscle pain and spasm, and promote deep, restorative sleep in patients with fibromyalgia. Examples of tricyclic antidepressants commonly used in treating fibromyalgia include amitriptyline (Elavil) and doxepin (Sinequan).