Clue Genetics

12/20/2025

The Quiet Crisis in Our Fields.

Fungal diseases are devastating crops globally, threatening our food supply and increasing the use of chemical pesticides. The same fungal chemistry in our library that fights human superbugs is delivering breakthrough compounds for natural crop defense. We are already testing licensed leads in the agricultural space. Your investment supports both a healthier planet and a more secure food future.

https://www.startengine.com/offering/clue-genetics

12/18/2025

From Fungal Goo to Pure Medicine.

We've moved past identifying promising extracts! From our initial Candida-active hits, our chemists have already successfully isolated 4 pure compounds for advanced testing. Identifying the exact active ingredient is a major, expensive hurdle in drug discovery, and we've successfully crossed it. This is the moment the science becomes real. Help us fund the next steps to structure identification and drug design.

https://www.startengine.com/offering/clue-genetics

12/17/2025

The science and strategy at Clue Genetics are guided by leaders with extensive experience in research and development. Today, we’re proud to highlight Dr. Cedric John Pearce, our Co-Founder, Principal Executive Officer, President, CTO, and Board Member.

Many years ago Dr. Pearce prepared his first new antibiotic and ever since has been actively involved with research and development of products from fungi and bacteria working in academia, large pharmaceutical firms and biotech companies. Dr. Pearce is an entrepreneur and for the past 25 years has been associated with companies he founded.

Dr. Pearce’s extensive experience contributes significantly to Clue Genetics’ direction and mission.

Learn more about our approach and ongoing work here:

https://www.startengine.com/offering/clue-genetics

12/16/2025

Finding Needles in a Haystack with Precision. Our 'Clue Platform' uses an advanced approach called Metabologenomics. It's not trial and error—it's smart science. We use custom software and advanced chemical analysis to quickly find the exact genes that create a specific, novel molecule. This precision is why we're moving so fast to deliver new solutions. Invest in the platform that’s built for breakthrough speed and accuracy.

https://www.startengine.com/offering/clue-genetics

12/13/2025

It's Not Enough to Kill the Bug—It Must Be Safe for Humans. Unlike many drug discovery projects, we integrate a mammalian cell toxicity assay early in our screening process. Our anti-Candida auris hits not only showed high activity, but they also showed no toxicity in these crucial initial tests. This critical data significantly de-risks our lead compounds and accelerates their path to becoming life-saving medicine. Help us advance these promising, non-toxic leads.

https://www.startengine.com/offering/clue-genetics

12/11/2025

A new scientific study has reported something extraordinary: 907 new fungal compounds were discovered in 2024—including a dramatic 153% jump in newly identified terpenoids, a major class of bioactive molecules.

This research shows how much untapped potential exists within fungi. Scientists continue to uncover compounds that could influence biotechnology, agriculture, and human health.

At Clue Genetics, we’re excited to see independent research validating the growing opportunity within fungal natural products.

Read the full study here:
https://www.tandfonline.com/doi/full/10.1080/21501203.2025.2526772



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Fungi have been recognised as a prolific source of structurally unique secondary metabolites with promising pharmacological properties. This review comprehensively summarises the chemical architect...

12/10/2025

Generating Revenue While Fighting Superbugs.

Our business model is designed for multiple revenue streams. We've successfully licensed leads for next-generation crop protection products to a third party. This foundational agreement positions us for substantial future royalty revenue, diversifying our business beyond human medicine. Invest in a company with early commercial traction and world-changing potential.

https://www.startengine.com/offering/clue-genetics

12/08/2025

The Untapped Frontier: 20+% New to Science. We believe nature holds the answers. Our vast, biodiverse fungal library is confirmed as unique—with over 20% of its species never before studied or new to science! This means our platform is exploring chemistry no one else has. Every investment helps us continue DNA fingerprinting these never-before-seen organisms to find truly novel molecules. Join us in unlocking a new era of natural products.

https://www.startengine.com/offering/clue-genetics

12/08/2025

12/06/2025

The Superbug Fight: We've Found a Major Clue. 💡

The CDC and WHO have flagged Candida auris as a top-concern global health threat. The good news? Our unique fungal library has delivered more than 10 strains highly active against in initial screens. Even better: they showed no toxicity in initial human cell tests! This means we’re ready to race forward with a novel, high-potential solution to an urgent problem. Invest in a breakthrough. Invest in Clue Genetics.

https://www.startengine.com/offering/clue-genetics

12/03/2025

Fungi have evolved extraordinary ways to build complex medicinal molecules — and scientists are finally learning how to read those instructions.

A new article from the University of Pennsylvania, “Nature’s instructions: How fungi make a key medicinal molecule” (ScienceDaily, Dec 2024), explains how biosynthetic gene clusters give fungi the ability to produce powerful natural compounds.

Source & full article:
https://phys.org/news/2024-12-nature-fungi-key-medicinal-molecule.html

If you’re curious about how our team works at the intersection of fungal genomics, AI, and natural-product discovery, visit our StartEngine page:
https://www.startengine.com/offering/clue-genetics

For roughly a century, ever since Alexander Fleming's accidental discovery of penicillin in 1928, fungi have proven to be a goldmine for medicines. They've provided treatments for a wide range of diseases, from infections and high cholesterol to organ rejection and even cancer.

11/18/2025

We Believe the Future is Fungal

At Clue Genetics, we are a team of expert chemists and biologists working to develop new medicines and other valuable natural products from fungi.

Fungi were one of the earliest forms of life to emerge on planet earth and they make an enormous array of biological molecules that have all kinds of potential applications.

Clue owns a very large collection of rare living fungal strains and we are mining these to identify candidates for treatment of challenging diseases.

We would like to invite you to join us on our journey - we are raising a round of equity via the StartEngine platform and we are welcoming new investors.

Visit our campaign page at: https://www.startengine.com/offering/clue-genetics

** Standard Disclaimer: This Reg CF offering is made available through StartEngine Primary, LLC, member FINRA/SIPC. This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment.

https://youtu.be/kNqeqfOJ10Y

At Clue Genetics, we are a team of expert chemists and biologists working to develop new medicines and other valuable natural products from fungi.Fungi were ...