02/11/2026
Let’s review MILRINONE!
✨ Milrinone is used in the NICU in babies with: Heart failure, post-cardiac surgery in the setting of decreased cardiac output, and pulmonary hypertension (including in the setting of congenital diaphragmatic hernia)
⭐️ Milrinone ↑ myocardial contractility and ↓ afterload by ↑ cAMP through phosphodiesterase III inhibition.
🛑 Milrinone is contraindicated in renal failure, or patients with history of ventricular arrhythmia.
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