02/21/2026
Case study. Real patient.
Female. Athletic. Eats clean. Lifts. Sleeps well. Does “everything right.”
Came in with low testosterone.
We started low-dose subcutaneous testosterone.
Also optimized progesterone.
First 4–6 months? She felt amazing.
• Libido up
• Leaner
• Gained muscle (and she was already fit)
• Energy solid
• Mood great
Then… she comes in and says,
“I don’t feel good.”
Fatigue.
Low motivation.
Almost a low-grade depressed feeling.
Waking up tired.
This is where experience matters.
I ran labs and checked SHBG (s*x hormone binding globulin).
Quick explanation:
SHBG is a protein made in the liver that binds to hormones like testosterone. When it’s high, it can “hold onto” your testosterone, meaning you have it on paper… but it’s not freely available to use.
Her SHBG had climbed.
So even though total testosterone looked fine, her body wasn’t getting access to it the same way.
And this is where knowing the patient matters.
I’ve seen her for years.
I know her baseline.
I know her personality.
I know her body composition.
I’ve seen her labs over time.
This isn’t something you catch from a Google search.
We backed down the testosterone slightly.
Ran a simple liver support / detox protocol (because SHBG is made in the liver).
Let her system recalibrate.
She’s healthy, so she responds fast.
Within weeks she started feeling like herself again.
Here’s the point:
Hormones are dynamic.
They move.
They adapt.
You can feel amazing on therapy… and then hit a wall. That doesn’t mean you “failed” testosterone. It means we reassess and adjust.
That’s why we check labs.
That’s why we don’t just guess.
That’s why individualized care matters.
If you’re considering testosterone therapy, it’s not one-size-fits-all. It’s monitored, adjusted, and personalized.
Text the office at 470-248-2050
if you’re ready for a personalized plan.
— Buket