ClearFlow, Inc.

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ClearFlow, Inc.

Minimize reinterventions with a pioneering catheter system that prevents blood and fluid retention in the chest cavity.

ClearFlow helps cardiac surgery professionals improve outcomes and advance healing through sustainable medical technologies that protect a patient's quality of life. Chest tubes used in heart and lung surgery frequently become obstructed by blood clots. When these tubes fail, the fluid can be retained; complications could include postoperative atrial fibrillation (POAF), acute kidney injury, or stroke. Reinterventions can slow recovery and bring a significant increase in the cost of care. The PleuraFlow® Active Clearance Technology® (ACT) System prevents chest tube failure and enables caregivers to manage postoperative bleeding safely, reliably, and efficiently. Reach out to our sales team here on LinkedIn or visit our website.

12/30/2025

Keep chest tubes clear after cardiac surgery.
Clogged chest tubes increase complications and hospital costs.
Watch how to implement the PleuraFlow® Active Clearance Technology® (ACT) System.

12/26/2025

Unlock Cost Savings and Superior Patient Outcomes with ClearFix

Achieve excellent patient outcomes while realizing meaningful cost savings across procedures.

ClearFix™ delivers uncompromised performance and lasting stability at an affordable price.

For the science behind plate fixation read: Orthopedic Principles to Facilitate Enhanced Recovery After Cardiac Surgery authored by Marc Gerdisch, MD, et al.

For a demo of the ClearFix Rigid Sternal Fixation system, please contact Tony Mathiason here on LinkedIn.

Read the full study here → 𝗢𝗿𝘁𝗵𝗼𝗽𝗲𝗱𝗶𝗰 𝗣𝗿𝗶𝗻𝗰𝗶𝗽𝗹𝗲𝘀 𝘁𝗼 𝗙𝗮𝗰𝗶𝗹𝗶𝘁𝗮𝘁𝗲 𝗘𝗻𝗵𝗮𝗻𝗰𝗲𝗱 𝗥𝗲𝗰𝗼𝘃𝗲𝗿𝘆 𝗔𝗳𝘁𝗲𝗿 𝗖𝗮𝗿𝗱𝗶𝗮𝗰 𝗦𝘂𝗿𝗴𝗲𝗿𝘆 - 𝗖𝗿𝗶𝘁𝗶𝗰𝗮𝗹 𝗖𝗮𝗿𝗲 𝗖𝗹𝗶𝗻𝗶𝗰𝘀 - https://www.criticalcare.theclinics.com/article/S0749-0704%2820%2930045-2/fulltext

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12/24/2025

Fact: Chest tubes occlude.
Fact: Occlusions cause retained blood.
Fact: Retained blood causes avoidable complications.

Solution: 𝗣𝗹𝗲𝘂𝗿𝗮𝗙𝗹𝗼𝘄® 𝗔𝗰𝘁𝗶𝘃𝗲 𝗖𝗹𝗲𝗮𝗿𝗮𝗻𝗰𝗲 𝗧𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆®
Proactive drainage management that works.

12/22/2025

How much difference can effective chest drainage make?

According to a new peer-reviewed study from Franciscan Health Indianapolis led by Dr. Marc Gerdisch, quite a lot.

In 1,334 cardiac surgery patients, using PleuraFlow® ACT within an ERAS cardiac program achieved:

• 𝟰𝟭% 𝗳𝗲𝘄𝗲𝗿 𝗿𝗲𝘁𝗮𝗶𝗻𝗲𝗱 𝗯𝗹𝗼𝗼𝗱 𝗰𝗼𝗺𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀
• 𝟭𝟳% 𝗳𝗲𝘄𝗲𝗿 𝗰𝗮𝘀𝗲𝘀 𝗼𝗳 𝗽𝗼𝘀𝘁𝗼𝗽𝗲𝗿𝗮𝘁𝗶𝘃𝗲 𝗮𝘁𝗿𝗶𝗮𝗹 𝗳𝗶𝗯𝗿𝗶𝗹𝗹𝗮𝘁𝗶𝗼𝗻
• 𝟯𝟬% 𝘀𝗵𝗼𝗿𝘁𝗲𝗿 𝗜𝗖𝗨 𝘀𝘁𝗮𝘆𝘀

These findings reinforce the clinical and operational value of active clearance in modern cardiac surgery recovery pathways.

Read the full study here → https://journals.sagepub.com/doi/full/10.1177/15569845251326084

12/19/2025

Surgery efficiencies, reduced costs, and overall better outcomes for your patients.

When you follow the evidence-based ERAS Cardiac Surgery Society around the use of Rigid Sternal Fixation systems, you improve your patients postoperative recovery, reduce complications, and save on your budget.

For the science behind plate fixation read: Rigid Plate Fixation Versus Wire Cerclage: Patient-Reported and Economic Outcomes From a Randomized Trial created by Keith Allen, Vinod Thourani, MD, Yoshifumi Naka, MD, PhD, Kendra J. Grubb, MD, MHA, FACC, MD, John Grehan, MD, PhD, Nirav Patel, MD, T. Sloane Guy, MD, Kevin Landolfo, MD, Marc Gerdisch, MD, FACS, FACC, FHRS, MD, Mark Bonnell, MD, and David J. Cohen, MD, MS.

For a demo of the ClearFix Rigid Sternal Fixation system,
reach out to Tony Mathiason here on Linkedin.

Check it out at https://lnkd.in/gtt28_jV

12/17/2025

Cardiac Surgeons are enjoying a 72% reduction in take-backs.

During the Arab Health Conference, Marc Gillinov, MD, Chairman of the Department of Thoracic and Cardiovascular Surgery at the Cleveland Clinic, spoke about the RCT from Montreal Heart Institute that found using Active Clearance Technology (per the ERAS Cardiac recommended guidelines) reduced reexploration significantly.

You can watch his entire webinar here: https://lnkd.in/dNgPU_Vj
And to avoid chest drain occlusion and prevent complications and hospital costs, you can find documentation on the PleuraFlow system that Dr. Gillinov mentions. https://clearflow.com/

12/15/2025

Reduce the incidence of complications after cardiac surgery with active maintenance of chest tube patency.

After heart surgery, the chest tube removes lost mediastinal blood. Clogging of the chest tube may induce inadequate evacuation of fluids surrounding the lungs and heart, leading to deadly consequences. This meta-analysis compared the effectiveness of active chest tube clearance (ATC) with conventional chest tube (CT) in lowering the incidence of retained blood complications after heart surgery. We conducted a systematic search of the available databases to identify cohort studies or clinical trials that met our inclusion criteria. Studies that compared active tube clearance and conventional tube in cardiac surgery were included. The fixed or random-effects model was used to determine the pooled effect estimates upon the heterogeneity of collected data. This review included 7003 people from five cohort studies and three clinical trials. This meta-analysis provides evidence on the positive effect of active maintenance of chest tube patency during the first hours of cardiac surgery, which resulted in reducing the incidence of complications.

More on this systematic review and meta-analysis can be found here: https://lnkd.in/gJUvd5gM

AUTHORS & AFFILIATIONS:
Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt
Mohammad Tarek Hasan, Abdulrahman Ibrahim Hagrass, Mohamed Nabil Elkhrashy, Mohamed Hamouda, Anas Zakarya Nourelden & Ahmed Bostamy Elsnhory
International Medical Research Association (IMedRA), Cairo, Egypt
Mohammad Tarek Hasan, Ibrahim Hagrass, Mohamed Nabil Elkhrashy, Mohamed Hamouda, Noura Mohamed shada, Sarah M. Hashem, Mohammed Al-kafarna, Hossam Waleed Almadhoon, Khaled Mohamed Ragab, Anas Zakarya Nourelden & Ahmed Bostamy Elsnhory
Gamal Abdel Nasser Axis, The 3rd Settlement, New Cairo, Egypt
Abdulrahman Ibrahim Hagrass
Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt
Noura Mohamed shada & Sarah M. Hashem
Faculty of Pharmacy, Al-Azhar University, Gaza, Palestine
Mohammed Al-kafarna
Faculty of Dentistry, Al-Azhar University, Gaza, Palestine
Hossam Waleed Almadhoon
Faculty of Medicine, Minia University, Minia, Egypt
Khaled Mohamed Ragab

CONTRIBUTIONS:
Conception and design of the work by Khaled Mohamed Ragab and Ahmed Bostamy Elsnhory.
Selection process and data collection by Mohammad Tarek Hasan, Mohamed Nabil Elkhrashy, Mohamed Hamouda, Noura Mohamed shada, and Sarah M. Hashem.
Data analysis and interpretation by Abdulrahman Ibrahim Hagrass and Khaled Mohamed Ragab.
Drafting the article by Mohammed Al-kafarna and Hossam Waleed Madhoon.
Critical revision and editing of the article by Abdulrahman Ibrahim Hagrass, Ahmed Bostamy Elsnhory, and Anas Zakarya Nourelden.

CORRESPONDING AUTHOR:
Correspondence to Abdulrahman Ibrahim Hagrass.

12/11/2025

Retained blood after surgery is common. It doesn't have to be. Clear chest tubes proactively with the PleuraFlow® Active Clearance Technology® (ACT) System.

Get started at https://clearflow.com/

12/05/2025

Improve outcomes after cardiac surgery.
Actively maintaining chest tube patency can reduce risk of RBS and hospital costs.

See how it works.

12/03/2025

Chest tube occlusion ➜ Retained blood ➜ Complications ➜ Longer stays.

Break the chain with PleuraFlow® Active Clearance Technology®

Proactive clearance. Proven outcomes. Positive ROI.

See the most recent published clinical study results below:

https://journals.sagepub.com/doi/full/10.1177/15569845251326084

12/01/2025

Surgery cost savings that improve outcomes for all hospital patients.

When you use the ClearFix Rigid Sternal Fixation system at your facility, you improve postoperative recovery, reduce complications, and save on budgets that can be redirected to improve facilities and equipment which contribute to better patient outcomes and quality of care.

For the science behind plate fixation read: Randomized, multicenter trial comparing sternotomy closure with rigid plate fixation to wire cerclage created by Keith Allen, Vinod Thourani, MD, Yoshifumi Naka, MD, PhD, Kendra J. Grubb, MD, MHA, FACC, MD, Grehan, MD, PhD, Nirav Patel, MD, T. Sloane Guy MD, Kevin Landolfo, MD, Marc Gerdisch, MD, FACS, FACC, FHRS, MD, Mark Bonnell, MD, and David J. Cohen, MD.

For a demo of the ClearFix Rigid Sternal Fixation system,
reach out to Tony Mathiason here on Linkedin.

Check it out at https://lnkd.in/gtt28_jV

Address

1630 S Sunkist Street, Ste E
Anaheim, CA
92806

Telephone

+17149165010

Website

https://www.clearflow.com/

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