01/24/2026
Abdominal pain can have causes that aren’t due to underlying disease. Many different conditions can cause abdominal pain. Examples include constipation, gas, overeating, stress, or muscle strain. Other causes of abdominal pain include appendicitis, cancer, abdominal aortic aneurysm, cholecystitis, diverticulitis, heartburn, indigestion, or gastroesophageal reflux (GERD). Diseases that can cause chronic abdominal pain include gastroesophageal reflux disease (GERD), Crohn’s disease, lactose intolerance, irritable bowel syndrome, or spastic colon. The main causes of abdominal pain are infection, abnormal growths, inflammation, obstruction (blockage), and intestinal disorders. Infections in the intestines and blood can cause bacteria to enter the digestive tract, resulting in abdominal pain. Some common causes of abdominal pain include diarrhea, constipation, stomach flu, and acid reflux when stomach contents leak backward into the esophagus.
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