11/18/2025
A new paper (co-authored by Dr. Michelle Hastings and more) was recently published in Nucleic Acids Research. The paper, “Modulating NLRP3 splicing with antisense oligonucleotides to control pathological inflammation” can be found here:
Inflammation has an essential role in healing. However, over-active inflammation disrupts normal cellular functions and can be life-threatening when not resolved. The NLR family pyrin domain-containing 3 (NLRP3) inflammasome, a component of the innate immune system, is an intracellular multiprotein....