11/11/2025
😬 If ‘disease creeps in through the gums’, it’s because the mouth is one of the body’s most active inflammatory zones — and a mirror of whole-body health.
In periodontal disease, oxidative stress overwhelms gum tissue and immune cells, disrupting redox balance and accelerating inflammation.
🥦 Sulforaphane, the bioactive phyto-compound in TRUEBROC®, activates the body’s master antioxidant defense — the Nrf2 pathway — helping restore resilience at the cellular level.
🧬 Emerging science:
• Sulforaphane restored glutathione levels and reduced oxidative burst in neutrophils from patients with chronic periodontitis (Dias et al., PLoS One, 2013; 8:e66407).
• SFN activated Nrf2 and reduced mitochondrial ROS and inflammatory mediators in human gingival fibroblasts challenged with P. gingivalis, while attenuating periodontal tissue damage in rats (Liu et al., Int Immunopharmacol, 2025).
• The Nrf2 pathway regulates antioxidant enzymes (HO-1, NQO1, SOD) critical to protecting gum tissue from inflammation and bone loss (Yang et al., Front Endocrinol, 2022).
🦷 These findings link oral health to the same antioxidant networks that TRUEBROC® supports systemically — reminding us that resilience begins at the cellular level.
TRUEBROC®
Proven in nature.
Rooted in science.
Made for resilience.