BioSurfaces LLC

04/03/2026

Some weeks test you—but they also remind you why you started.

At BioSurfaces, we’ve always taken the long road: building real science, staying honest about our technology, and putting customers first. In a world where hype can outpace substance, that hasn’t always been the easy path.

But here’s the “little secret”…

Our IVRT business is growing fast. Without massive spending, without noise just real results. Our Bio-Spun® scaffolds are gaining traction because they work, and our customers are seeing it firsthand.

At the same time, we’re seeing renewed interest in technologies like our NuSpun™ Vascular Graft and Bio-Spun® Fistula Plug, along with more companies reaching out to collaborate and co-develop solutions. After years of steady work, it feels like the momentum is building.

We may be the “best kept little secret”… but maybe not for much longer.

Check Out the Newest Blog Here: https://www.biosurfaces.us/single-post/week-3-best-kept-little-secret

03/27/2026

Fantastic week at ! Dr. Patrick Hayden presented three posters showcasing our advancements in next-generation in vitro models—including full-thickness bronchial epithelium, a dynamic tri-cell intestinal model, and a reproducible full-thickness skin model—all built on our Bio-Spun® electrospun scaffold platform. We had great engagement and valuable discussions with researchers across the field.

👉 View all posters on our website: https://www.biosurfaces.us/posters

#2026

03/20/2026

We’re excited to share that Dr. Patrick Hayden will be presenting posters at the Society of Toxicology (SOT) 2026 Annual Meeting with three cutting-edge posters highlighting advancements in human-relevant in vitro models:

🔬 Poster Board M814 (Wednesday 3/25 - 1:45pm)
Next-generation full-thickness human bronchial epithelial model produced using 3D electrospun scaffolds and animal-component-free culture media

🔬 Poster Board M816 (Wednesday 3/25 - 1:45pm)
A Tri-Cell Culture Model of Human Intestine Constructed on Electrospun Polyurethane Scaffold Inserts in the MIVO Millifluidic Device: Effect of Static vs. Dynamic Flow Culture Conditions

🔬 Poster Board J658 (Tuesday 3/24 - 1:45pm)
Protocol Transfer and Reproducibility of an Electrospun Scaffold-based In Vitro Human Full-thickness Skin Model

These posters showcase the power of electrospun scaffold technology in advancing physiologically relevant, animal-free tissue models across respiratory, intestinal, and dermal systems.

If you’re attending SOT 2026, be sure to stop by and connect!

03/13/2026

Introducing the first 96-Well High Throughput Screening (HTS) plates designed for building Full Thickness Tissue Models.

Our Bio-Spun® scaffold enables researchers to create physiologically relevant tissue models in a scalable 96-well HTS format using their own cells.

Learn more and order here: https://www.biosurfaces.us/ivrtstore

02/27/2026

Week 2 is live: Bio-Spun® — The Swiss Army Knife of Biomaterials 🔬

After 22+ years of innovation, trial, and persistence, Bio-Spun® has evolved into a platform technology powering everything from medical devices to human tissue models and advanced research tools.

How did the name Bio-Spun® come to life — and why do we call it the Swiss Army Knife of biomaterials?

👉 Read the full story and see where Bio-Spun® is headed next.
🔗 https://www.biosurfaces.us/single-post/week-2-bio-spun-the-swiss-army-knife-of-biomaterials

Hope you all are doing well. As you might have heard, we recently announced that the name for our technology, which we call Bio-Spun, is now a registered trademark (Bio-Spun®). This was exciting news as it provides the company with a strong marketing tool to bring brand recognition to our electrosp...

02/20/2026

Big news for research teams — the In Vitro Research Tools (IVRT) products from BioSurfaces now features updated pricing, making it even easier to access our 3D scaffold technology designed to better replicate native tissue environments. These scaffolds enable more physiologically relevant models, improved cell behavior, and enhanced translational insight—using the same trusted tools researchers rely on to advance , , and .

Check it out here!
https://www.biosurfaces.us/ivrtstore

02/13/2026

🎉 Big milestone for innovation at BioSurfaces 🎉

We’re proud to announce that Bio-Spun® is now a registered trademark.

This achievement reflects years of science-driven innovation and our commitment to developing biomaterials that mimic the body’s extracellular matrix. Securing the Bio-Spun® name reinforces what it stands for: differentiation, credibility, and a platform built to advance healing.

Thank you to our team, partners, and supporters who helped make this milestone possible. The journey continues and we’re just getting started.

02/06/2026

🔄 Reintroducing Our Spin Cycle Page
Your Monthly Hub for Fresh Insights and Updates

What if your in vitro models delivered human-relevant data—without animal-derived components?

With Bio-Spun™ Scaffolds, BioSurfaces is redefining how researchers build predictive, reproducible tissue models. Engineered to replicate the body’s natural extracellular matrix, Bio-Spun™ eliminates the variability of animal-derived materials while supporting advanced tissue development across multiple organ systems in .

From airway and skin models developed in-house to intestinal and retinal models built and validated by our customers, Bio-Spun™ scaffolds are powering next-generation platforms—from bioprinting to organ-on-chip—designed for science.

Dive into this month’s Spin Cycle to explore real tissue models, customization options, and how animal-free scaffolds are helping advance .

👉 Read more: https://www.biosurfaces.us/spin-cycle

01/27/2026

Week 1 – Optimist vs. Realist – The Struggle Is Real

What happens when a lifelong scientific optimist runs head-first into the realities of biotech entrepreneurship?

In this week’s blog, Matt shares an honest look at fundraising, stalled deals, broken partnerships, and why optimism fuels discovery—but doesn’t always translate cleanly to business. He also highlights why IVRT and Bio-Spun™ scaffolds give us confidence as momentum builds toward more human-relevant, non-animal testing models.

If you’ve ever balanced hope with hard-earned realism, this one will resonate.

👉 Read the full post: https://www.biosurfaces.us/single-post/week-1-optimist-vs-realist-the-struggle-is-real

01/16/2026

We’ve been laying the groundwork for what’s next — and we’re excited to start sharing it.

Over the coming weeks/months, we’ll be releasing a new publication based on our In Vitro Research Tools (IVRT) and the benefits of our material for tissue model development, alongside a new and improved Spin Cycle page that dives into new data and updated insights. We’re also putting the finishing touches on an IVRT animation, scheduled to drop next month, that brings the work to life in a new way.

There’s a lot ahead, and this is just the beginning. Stay tuned for what’s coming next.

01/09/2026

The U.S. Senate has unanimously passed the FDA Modernization Act 3.0, directing FDA to update drug regulations to reflect modern nonclinical testing approaches, including in vitro and other human-relevant methods.

As regulators continue to embrace New Approach Methodologies (NAMs), platforms like BioSurfaces’ IVRT (In Vitro Research Tools) are increasingly important. BioSurfaces’ IVRT platform supports nonclinical research by enabling reproducible, human-relevant in vitro data generation—aligned with FDA’s push to modernize drug development and reduce reliance on animal testing.

This legislation reinforces a clear direction: future-ready science will be human-relevant, data-driven, and in vitro–enabled.

Learn more about BioSurfaces’ IVRT products: https://www.biosurfaces.us/ivrt

12/19/2025

✨ Week 11 – Reflecting on a Busy Year at BioSurfaces ✨

As we close in on the end of the year, Matt shares an inside look at how far our small-but-mighty team has come — from strengthening our investor messaging to seeing global growth in our Bio-Spun™ IVRT product line.

2024 began with uncertainty, but 2025 has far exceeded expectations. We’ve:
🔹 Expanded our customer base and global distribution
🔹 Seen strong validation of our Bio-Spun™ scaffolds across new tissue models
🔹 Continued to innovate in cell therapy, medical devices, and internal technologies
🔹 Restarted key programs including our NuSpun™ Vascular Graft and Bio-Spun™ Fistula Plug

There’s nothing better than seeing years of hard work start turning into real traction — and we're heading into 2026 with momentum and optimism.

Matt also reflects personally on the challenges, the wins, and the support of our readers who follow our journey each week.

Read the full Week 11 blog here: https://www.biosurfaces.us/single-post/week-11-reflecting-on-a-busy-year

And from all of us at BioSurfaces — wishing you a warm, healthy, and happy holiday season!