02/20/2026
👉 Parents of toddlers—ask your allergist about dosing options.
Why 500 mg? It wasn’t random—and it wasn’t about pushing limits.
In this clip, Dr. Alice Hoyt explains how preschool OIT dosing decisions came directly from published data and real-world outcomes—not guesswork.
• Cleveland Clinic preschool data compared 300 mg vs 3000 mg peanut protein
• Both groups reached the same level of tolerance
• Higher-dose kids experienced more reactions
• Lower dosing offered the same benefit with better safety
• 500–600 mg (about half a teaspoon) became a practical, family-friendly solution
Lower dose didn’t mean less effective—it meant fewer reactions and a more feasible approach for families.
If you’re a parent navigating food allergy decisions and unsure what dosing options make sense for your toddler, expert guidance matters.
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