12/29/2025
Do you suffer from chronic migraines? 😑
Migraines affect millions of people and can be deeply debilitating, often involving throbbing head pain, light or sound sensitivity, nausea, visual disturbances, brain fog, and fatigue that interfere with daily life.
What’s often at the root? Histamine.
Histamine is a powerful inflammatory messenger. When it builds up faster than your body can clear it, your migraine threshold drops.
How can you develop a histamine buildup?
There are many factors that increase histamine:
➡️ Chronic stress – increases histamine release and slows clearance
➡️ Gut issues - H. pylori, SIBO, parasites, and Candida can increase histamine production and reduce DAO (the enzyme that breaks down histamine)
➡️ Environmental toxins- mold and chemical exposures activate mast cells, which release histamine
➡️ Food allergies/sensitivities – gluten, dairy, and high-histamine foods (aged cheese, fermented foods, alcohol, leftovers)
➡️ Hormonal shifts - estrogen amplifies histamine signaling (common trigger around menstruation)
➡️ Mitochondrial dysfunction & methylation issues – impair histamine breakdown
When we address these root causes, the migraine threshold rises, inflammation calms, and many people experience fewer, less intense migraines, or they disappear completely.
👉Swipe through for details on the histamine-migraine connection, and comment “Guide” for my Low Histamine Diet Quick Start Guide.
Dr. Ann