The Jackson Laboratory

The Jackson Laboratory Est. 1929, JAX is a non-profit scientific research institute specializing in genetics, genomics & mouse models of disease. www.jax.org Cancer. Diabetes.

Alzheimer’s. Heart Disease. Parkinson’s. The Jackson Laboratory (JAX) leads the search to cure diseases rooted in our DNA. We are an NCI-designated cancer center and an independent 501(c)3 nonprofit organization with over 90 years of experience in genetics and genomics research. JAX blends the brightest minds with state-of-the-art resources to accelerate discovery. Areas of Discovery (>60 Principal Investigators, >250 Ph.D.s, M.D.s, and D.V.M.s):
• Cancer: We are a National Cancer Institute designated Cancer Center focusing on cancer initiation, progression, prevention and therapies.
• Developmental/reproductive biology: birth defects, Down syndrome, osteoporosis, fertility
• Immunology: HIV-AIDS, anemia, autoimmunity, cancer immunology, immune disorders, lupus, transplant rejection
• Metabolic diseases: atherosclerosis, cardiovascular disease, diabetes, high blood pressure, obesity, microbiome
• Neurobiology: blindness, Parkinson’s, Alzheimer’s, deafness, epilepsy, glaucoma, macular degeneration, neurodegenerative diseases
• Neurobehavioral disorders: autism, addiction, depression

Supporting Global Research:
• The JAX Mouse Repository and Scientific Services are among the premier resources available for biomedical research. Committed to Education:
• Summer Student Program (undergrad & high school)
• Teaching the Genome Generation Short Course
• Ph.D. programs: U. Maine, Tufts University and U. Connecticut
• Courses, Conferences and Workshops

Support The Jackson Laboratory: https://www.jax.org/give-to-jax

A key cancer-fighting gene in leukemia is switched off—not broken—and scientists from The Jackson Laboratory (JAX) found...
04/02/2026

A key cancer-fighting gene in leukemia is switched off—not broken—and scientists from The Jackson Laboratory (JAX) found a way to switch it back on.

In a recent study published in Science Translational Medicine and led by JAX Assistant Professor Eric Wang, the team revealed not only a potential new way to treat acute myeloid leukemia (AML) without harsh chemotherapy, but also a promising strategy to study more gene-silencing mechanisms in other diseases.

Researchers created a CRISPR-based tool to pinpoint genes the cancer turns off

Congratulations to Arunachalam Sekar and Luke Trinity for being named this year's JAX Scholars. The fellowship supports ...
04/01/2026

Congratulations to Arunachalam Sekar and Luke Trinity for being named this year's JAX Scholars. The fellowship supports outstanding postdoctoral associates as they advance the understanding of mammalian biology and human disease.

Learn more about this year's scholars and how they stand out for their innovative approaches to complex questions:

Two postdocs honored for their contributions to research on mitochondria, heart failure, and the immune system.

03/31/2026

Watch the full video and read the story: go.jax.org/EndoRISE33126

JAX, UConn Health, and the state of Connecticut established a first-of-its-kind, coordinated ecosystem, EndoRISE, aligned around a shared goal to accelerate discovery and improve outcomes for a systemic disease disrupting millions of lives: endometriosis.

When endometrium-like tissue grows outside of the uterus, it causes whole-body inflammation, scarring, and severe pain, yet it is deeply misunderstood despite its prevalence.

03/31/2026

🎞️ Full video live now at jax.org

1 in 10: The endometriosis challengePremieres tomorrow. 🎬 🔔 Set a reminder to watch live: https://youtu.be/2K4tUnWQmFc
03/30/2026

1 in 10: The endometriosis challenge

Premieres tomorrow. 🎬

🔔 Set a reminder to watch live: https://youtu.be/2K4tUnWQmFc

What’s taking shape in Connecticut is more than a research initiative. It’s a model for how states can take on complex, underfunded diseases in a coordinated...

03/27/2026

Endometriosis is common, yet still deeply misunderstood.

EndoRISE is a collaborative engine—bringing together JAX, UConn Health, and the state of Connecticut—to advance progress in endometriosis research, innovation, support, and education.

See how we're addressing the endometriosis challenge on March 31.

Huge congratulations to Mark Adams, professor and interim scientific director at The Jackson Laboratory (JAX) for Genomi...
03/26/2026

Huge congratulations to Mark Adams, professor and interim scientific director at The Jackson Laboratory (JAX) for Genomic Medicine, who has been elected a 2025 Fellow of the AAAS - The American Association for the Advancement of Science, one of the most distinguished lifetime honors for scientists.

Adams is among nearly 500 scientists, engineers, and innovators recognized as AAAS 2025 Fellows for their lifetime career achievements. His pioneering contributions to DNA sequencing technology and key roles in mapping early genomes — including the human genome — represent foundational work that underpins much of today’s research into cancer, rare disease, and precision medicine.

Read the full announcement: https://go.jax.org/Adams-AAAS

03/25/2026

Henry thought a stage IV prostate cancer diagnosis would mean hours on the road to distant specialists. Instead, world-class genomic cancer care came to his island community through The Maine Cancer Genomics Initiative (MCGI).

A carpenter for 50 years and happiest outdoors, Henry is focused on what matters most: time with family and another chance to keep going.

Learn how genomic care made a difference: go.jax.org/HenryMCGI

03/25/2026

Worthington Scholars & alumni: If you’re thinking about what comes after graduation and are interested in a career in biomedical research, check out this new opportunity.
The Worthington–JAX Postbac Researchers program — offered in partnership with The Jackson Laboratory — is a two-year, paid research training experience in Bar Harbor, Maine.
The program includes:
✅ $45,032 annual salary
✅ Health insurance
✅ Access to low-cost JAX housing
✅ Structured mentorship and professional development

As a Worthington–JAX Postbac Fellow, you’ll contribute to cutting-edge research, pursue an independent project connected to human health and disease, and receive built-in support through biweekly meetings, journal club, training in data science and science communication, and individualized graduate school application advising.

📅 Applications are due May 4, 2026!

Learn more and explore eligibility: https://www.jax.org/education-and-learning/pre-and-postdoctoral-program/postbac-at-jax/worthington-scholarship-foundation-postbac-researchers?utm_source=facebook&utm_medium=social&utm_content=worthington_scholars

If you’re part of the Worthington community or know someone who is, please help spread the word by sharing this opportunity.

03/23/2026

What happens when researchers, clinicians, advocates, and policymakers build something together?

See how JAX, UConn Health, the state of Connecticut, and EndoRISE are addressing the endometriosis challenge on March 31.

Congratulations to all students who participated in this year’s Connecticut Science & Engineering Fair, a celebration of...
03/21/2026

Congratulations to all students who participated in this year’s Connecticut Science & Engineering Fair, a celebration of curiosity, creativity, and the power of young scientists to ask big questions.

Your work represents the future of biomedical research and we can’t wait to see where it leads.

Read our latest post about this year's fair at: https://go.jax.org/wj31l7

🎉 We’re especially proud to congratulate the first-ever recipients of the Jackson Laboratory Computational Biology and Bioinformatics Award, recognizing outstanding student work at the intersection of data, mathematics, and biology:

• Jessica Garcia (Middlebrook School)
• Juliette Prezioso (Central Middle School)
• Pierson Clark (Slate School)
• Shravya Mankala, Scarlett Chen, & Jiayu Su (Bethel High School)
• Rhea Doshi (Kingswood Oxford)
• Tessa Addeo (Greenwich High School)

03/20/2026

When doctors diagnose a brain tumor, they often face a high-stakes mystery: Is it slow-growing and treatable or aggressive and deadly? Through cutting-edge testing, JAX scientists are helping to more accurately diagnose brain tumors - and changing the lives of patients in the process.
Learn more: https://www.jax.org/news-and-insights/2025/may/precision-brain-cancer-diagnosis 🧠

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600 Main Street
Bar Harbor, ME
04609

Telephone

+12072886000

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Our Story

Cancer. Diabetes. Alzheimer’s. Heart disease. Parkinson’s... The Jackson Laboratory (JAX) leads the search to cure diseases rooted in our DNA. We are an independent 501(c)3 nonprofit organization with 90 years of experience in genetics and genomics research. In addition to 70+ research labs, we house many National Institutes of Health-funded Research Centers and have a rich curriculum of both in-person and online courses and workshops in genetics and genomics.

JAX has its mammalian genetics headquarters in Bar Harbor, Maine; a Genomic Medicine institute in Farmington, Conn.; and facilities in Sacramento, Calif., Ellsworth, Maine and Shanghai, China.

Areas of Discovery (>75 Principal Investigators, >250 Ph.D.s, M.D.s, and D.V.M.s): • Cancer: We are a National Cancer Institute (NCI)-designated Cancer Center focusing on cancer initiation, progression, prevention and therapies. • Developmental/reproductive biology: birth defects, Down syndrome, osteoporosis, fertility • Immunology: HIV-AIDS, anemia, autoimmunity, cancer immunology, immune disorders, lupus, transplant rejection • Metabolic diseases: atherosclerosis, cardiovascular disease, diabetes, high blood pressure, obesity, microbiome • Neurobiology: blindness, Parkinson’s, Alzheimer’s, deafness, epilepsy, glaucoma, macular degeneration, neurodegenerative diseases • Neurobehavioral disorders: autism, addiction, depression Supporting Global Research: • The JAX Mouse Repository and Scientific Services are among the premier resources available for biomedical research. • 2.5 million JAX® Mice are distributed annually to more than 900 institutions in 56 countries. Committed to Education: • Summer Student Program (undergrad & high school) • Teaching the Genome Generation Short Course • Ph.D. programs: U. Maine, Tufts University and U. Connecticut • Courses, Conferences and Workshops Support The Jackson Laboratory: https://www.jax.org/give-to-jax