02/14/2026
Colon Cancer Screening: Understanding Your Options
Screening for colon cancer can help find cancer early—or even prevent it. Most adults at average risk should start screening at age 45. There are a few different tests, and each one works a little differently.
Colonoscopy is the most thorough test. A doctor looks at the entire colon and can remove polyps before they turn into cancer. If the test is normal, it’s usually only needed every 10 years. It does require a bowel prep the day before and sedation during the procedure.
FIT (F***l Immunochemical Test) is a simple at‑home test done once a year. It checks for hidden blood in the stool, which can be a sign of cancer. It’s easy and non‑invasive, but it cannot remove polyps. If the result is abnormal, a colonoscopy is needed.
Cologuard® is also an at‑home test, done every 3 years. It looks for both blood and certain DNA changes linked to colon cancer. It can find more cancers than FIT alone, but abnormal results still require a colonoscopy.
The most important thing: getting screened. The best test is the one you are willing to complete—and repeat on schedule—with follow‑up if needed.
Talk with your healthcare provider about which option is right for you.
Discover Cologuard® and Cologuard Plus™ noninvasive colon cancer screening tests for adults 45+ at average risk. Collect at home and ship to the lab. Rx only. See risk info.