02/23/2026
Major national coverage for Kaiser Permanente's (that we co-authored with researchers from USC and UCSF) new JAMA Health Forum study. NPR’s Rhitu Chatterjee featured our research on Weekend Edition Saturday, highlighting findings from one of the largest longitudinal studies to date examining adolescent cannabis use and mental health outcomes.
Researchers followed 460,000 adolescents in the Kaiser Permanente system through age 25. After excluding teens with prior psychiatric symptoms, the study found:
• More than double the risk of psychotic disorders
• Roughly double the risk of bipolar disorder
• A one-third increase in depression
• A one-quarter increase in anxiety
As Dr. Lynn Silver explained to NPR, the adolescent brain is still developing — and regular cannabis use may disrupt healthy neural development in ways that increase vulnerability to serious psychiatric disorders. She also underscored that legalization has contributed to a widespread perception of cannabis as a harmless, natural stress remedy — a perception not supported by emerging evidence.
Grateful to NPR for thoughtful, careful coverage of this research.
See article: https://www.npr.org/2026/02/21/nx-s1-5719338/cannabis-ma*****na-weed-teens-psychosis-jama
*****na Public Health Institute NPR
Researchers followed more than 400,000 teens until they were adults. It found that those who used ma*****na were more likely to develop serious mental illness, as well as depression and anxiety.