11/14/2025
Another Reason Why Shifting Away From Botox for Migraine Is the Right Choice
New data continues to confirm that Botox is not effective for episodic migraine, defined as 6–14 migraine headache days per month. This matters because episodic migraine represents more than 90% of all migraine cases in the U.S.
That means the vast majority of patients we see simply do not benefit from Botox as a preventive option.
As clinicians, we must continuously adapt to evidence. With stronger results coming from CGRP medications, gepants, neuromodulation therapies, lifestyle programs, and individualized preventive strategies, it’s clear that moving away from Botox for episodic migraine is the right decision for our patients.
Our responsibility is to offer treatments that work — and the data is pointing us in a new direction.
Patricio Sebastian Espinosa
Espinosa Neuroscience Institute
International Neurology Foundation