Espinosa Neuroscience Institute

04/25/2026

04/22/2026

Memory loss to be concerned of?

Patricio Sebastian Espinosa
Espinosa Neuroscience Institute

04/21/2026

🚨 Important FDA Safety Update for Parkinson’s Disease Patients & Caregivers 🚨

The FDA has updated the prescribing information for carbidopa/levodopa products after reports of seizures linked to Vitamin B6 deficiency in patients taking higher doses.

Products affected include:
Sinemet, Rytary, Duopa, Crexont, Vyalev, Dhivy, and others.

Key Findings:

🔹 Reported seizure cases were mostly in patients taking more than 1000 mg/day of levodopa
🔹 Risk appeared higher above 1500 mg/day
🔹 Some patients developed status epilepticus
🔹 Standard seizure medications often did not work
🔹 Many improved after Vitamin B6 supplementation

What This Means:

If you or a loved one has Parkinson disease and takes carbidopa/levodopa, ask your doctor about:

✅ Checking Vitamin B6 levels before starting treatment
✅ Periodic monitoring while on therapy
✅ Watching for symptoms such as confusion, neuropathy, anemia, or seizures
✅ Reviewing high-dose levodopa regimens

My Perspective as a Neurologist:

This is an excellent reminder that sometimes neurological symptoms are not disease progression—but a treatable vitamin deficiency.

Simple lab monitoring may prevent serious complications.



Patricio Sebastian Espinosa

04/17/2026

🧠 Not All Memory Loss Is Alzheimer’s: Think Normal Pressure Hydrocephalus (NPH)

Many patients are told their symptoms are just “aging” or dementia…
But sometimes, it’s something treatable.

📍 Normal Pressure Hydrocephalus (NPH) is a condition where excess cerebrospinal fluid enlarges the brain ventricles — and it can be reversible.

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⚠️ The Classic Triad:

✔️ Gait disturbance (walking becomes slow, wide-based, “magnetic”)
✔️ Cognitive decline (memory and attention issues)
✔️ Urinary incontinence

👉 Often, the walking problem comes first — and is the most important clue.

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📸 What do we see on MRI?

* Enlarged ventricles (Evans Index > 0.30)
* In this case: Evans Index ≈ 0.55 → markedly abnormal
* Narrowed callosal angle
* Sometimes a pattern called DESH

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💡 Why this matters:

NPH is one of the few causes of dementia that can be treated.

🛠️ Treatment may include:

* High-volume lumbar puncture (diagnostic & therapeutic)
* Ventriculoperitoneal (VP) shunt

👉 Early diagnosis = better outcomes

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🚨 Clinical Pearl:

If a patient has difficulty walking + memory issues,
always consider NPH before labeling dementia.

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📍 At Espinosa Neuroscience Institute, we focus on advanced neuroimaging and early diagnosis to improve patient outcomes.

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👉 Have you seen a patient like this?
Drop your thoughts or questions below.


Patricio Sebastian Espinosa
Espinosa Neuroscience Institute

04/16/2026

Not all neurological symptoms should wait..

Patricio Sebastian Espinosa
Espinosa Neuroscience Institute

04/16/2026

With Universidad Central Del Ecuador – I'm on a streak! I've been a top fan for 3 months in a row. 🎉

04/16/2026

This amazing technology available Espinosa Neuroscience Institute

🧠😎🧠

It was a pleasure seeing my friends from Hyperfine (Swoop portable MRI) at the Boca Raton Regional Hospital Foundation Philanthropy Gala.

Proud to share that our community was among the first in Florida to adopt this groundbreaking technology. The Swoop Portable MRI has helped transform access to neuroimaging—bringing MRI directly to the point of care and allowing patients to receive faster imaging, quicker diagnoses, and more timely treatment.

This type of innovation is redefining neurological care—improving accessibility, efficiency, and ultimately patient outcomes.

Grateful to be part of a community that continues to support both medical innovation and meaningful philanthropy.



Patricio Sebastian Espinosa

04/15/2026

🧠 Your Brain Has a “Backup System”… And It Matters More Than You Think

Even in people genetically destined to develop Alzheimer’s, some stay sharp for years longer than others.

Why?
👉 It’s called Cognitive Reserve — your brain’s ability to compensate and adapt.

New research shows:
• Higher reserve = delayed symptoms
• Better function despite brain changes
• But once reserve runs out → symptoms progress faster

💡 The powerful part?
You can build cognitive reserve.

✔️ Education & lifelong learning
✔️ Mental stimulation
✔️ Social engagement
✔️ Brain-healthy lifestyle

🔬 Bottom line:
Your brain is more resilient than you think — but timing matters.

The earlier you invest in brain health, the longer you may protect your cognition.

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🧠 Espinosa Neuroscience Institute
Advancing brain health through science, prevention, and innovation
Patricio Sebastian Espinosa
Espinosa Neuroscience Institute