11/07/2025
Among people with an opioid use disorder, SAMHSA highlighted that about 4.8 million met criteria in 2024; of those, roughly 17% received medications for opioid use disorder (MOUD) during the year. That gap between need and medication treatment remains one of the most stubborn problems in the response.
The numbers behind the U.S. opioid epidemic have shifted in 2025 in ways that feel both hopeful and complicated. Nationally, fatal overdoses have fallen from