04/04/2023
WHAT TO KNOW ABOUT MALARIA, AND ITS CAUSES
Malaria is a serious and sometimes fatal disease caused by the Plasmodium parasite, which is transmitted to humans through the bites of infected Anopheles mosquitoes. Malaria is a major public health problem in many parts of the world, particularly in sub-Saharan Africa, where it is responsible for a significant number of deaths each year.
Symptoms of malaria can include fever, headache, chills, muscle aches, and fatigue. In severe cases, malaria can cause organ failure, coma, and death. The symptoms of malaria usually appear 10-15 days after a person is bitten by an infected mosquito, although in some cases it can take several weeks or even months for symptoms to appear.
There are several species of Plasmodium parasite that can cause malaria in humans, but the deadliest form is caused by the Plasmodium falciparum parasite. Other species of Plasmodium that can cause malaria in humans include Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae.
Malaria can be prevented through a number of measures, including the use of insecticide-treated bed nets, indoor residual spraying with insecticides, and the use of antimalarial drugs. In addition, efforts to control the mosquito populations that transmit the disease, such as draining standing water where mosquitoes breed, can also be effective.
Treatment for malaria typically involves the use of antimalarial drugs, such as chloroquine, artemisinin-based combination therapies, or other drugs depending on the type of malaria and its severity. However, drug resistance has become an increasing problem in some parts of the world, making it more difficult to treat the disease effectively.
Overall, malaria remains a significant global health challenge, particularly in low-income countries with limited resources for prevention and treatment. Efforts to develop new vaccines, drugs, and other interventions are ongoing, but much work remains to be done to eliminate this deadly disease
DRUGS/MEDICINES USED FOR IT
Malaria is treated using medications that target the Plasmodium parasite, which causes the disease. The choice of medication depends on several factors, including the species of Plasmodium causing the infection, the severity of the disease, and the patient's age and medical history.
The most common medications used to treat malaria include:
1. Artemisinin-based combination therapy (ACT): This is the recommended treatment for uncomplicated malaria caused by Plasmodium falciparum, which is the most deadly species of Plasmodium. ACT combines an artemisinin derivative with a longer-acting partner drug, such as mefloquine or lumefantrine.
2. Chloroquine: This medication is used to treat malaria caused by Plasmodium vivax, Plasmodium ovale, and some strains of Plasmodium malariae. However, chloroquine-resistant strains of Plasmodium have emerged in many parts of the world, and alternative medications are often needed.
3. Quinine: This medication is used to treat severe malaria, as well as malaria caused by chloroquine-resistant strains of Plasmodium. Quinine is usually given intravenously in a hospital setting.
4. Primaquine: This medication is used to eliminate the dormant liver-stage parasites that cause relapses of malaria caused by Plasmodium vivax and Plasmodium ovale.
In addition to medications, supportive care may be needed to manage complications of severe malaria, such as dehydration, anemia, and organ failure. Prevention measures, such as the use of insecticide-treated bed nets and anti-malarial medication for travelers to high-risk areas, can also help to reduce the incidence of malaria.
ANTIBIOTICS USED IN TREATING OF MALARIA
Antibiotics are not typically used to treat malaria. Malaria is caused by a parasite called Plasmodium, which is not a bacterium that can be treated with antibiotics. Instead, anti-malarial medications such as artemisinin-based combination therapy (ACT), chloroquine, quinine, and primaquine are used to treat malaria. These medications work by targeting the Plasmodium parasite at various stages of its life cycle.
It is important to note that the inappropriate use of antibiotics for conditions that are not caused by bacteria can contribute to the development of antibiotic resistance, which is a growing global health concern. Therefore, antibiotics should only be used when they are prescribed by a healthcare professional for bacterial infections.
The most effective drug for malaria depends on several factors such as the age, health condition of the patient, etc. Some of the commonly used medications include:
• Chloroquine (Aralen)
• Doxycycline (Vibramycin, Oracea, Adoxa, Atridox)
• Quinine (Qualaquin)
• Mefloquine (Lariam)
• Atovaquone/proguanil (Malarone)
Artemisinin Combination Therapies (ACTs) are also usually preferred for chloroquine-resistant malaria
RECOMMENDATION: USE TETRACYCLINE WITH MALARIA DRUGS AND IRON (FERRUS SULFATE) WITH ACETAMINOPHEN FOR YOUR MALARIA TREATMENTS.