McCance Center for Brain Health at MGH

12/23/2025

Protect your brain health by keeping a close eye on your plate during holiday festivities. Make a plan in advance with our tips for making brain-healthy choices. For more healthy habits: massgeneral.org/neurology/mccance-center/about/shield

12/18/2025

More coverage of the study out in Nature Neuroscience this week. Read the ScienceBlog.com post featuring McCance Director, Dr. Rudy Tanzi here: scienceblog.com/the-protein-destroying-alzheimers-brains-may-have-once-saved-them/

12/17/2025

A new paper in Nature Neuroscience by McCance researchers shows the brain’s antiviral defense mechanisms may trigger Alzheimer’s. Read about it here:

Mass General Brigham researchers found that hyperphosphorylated tau, the main component of pathological tangles in Alzheimer’s disease, may help protect the brain from infection.

12/16/2025

A must-watch presentation by McCance Center Director Dr. Rudy Tanzi!

With lifespans rising faster than health spans, brain health is more important than ever. In his presentation, Dr. Rudy Tanzi shares the latest in Alzheimer’s disease research, treatment, and prevention, and explains how lifestyle strategies can help lower the risk for the disease and keep the brain healthy.

Link to https://ow.ly/GQJL50XK1J2

12/12/2025

McCance-affiliated faculty explore new personalized treatment possibilities with the use of AI. Read the article:

AI, statistics offer new possibilities for personalized medicine.

12/10/2025

Do you have a PhD in neurobiology, immunology, bioengineering, stem cell biology, or a related field? Looking for a postdoctoral fellowship? The labs of McCance Center-affiliated faculty, Dr.
Jorfi and Dr. Griciuc in the MGH Genetics and Aging Research Unit seek a Postdoctoral Fellow to conduct research in neuroimmunology.

Check out the job description here: https://bit.ly/GARUPD

12/09/2025

Listen in as Dr. Rudy Tanzi & Dr. Edmarie Guzman-Velez explore the results of this McCance-sponsored trial.

12/09/2025

McCance Center Director, Dr. Rudy Tanzi, shares key brain health tips in this Newsweek piece: newsweek.com/6-natural-ways-protect-brain-backed-neurologist-11140872

12/03/2025

Come join the McCance Center team! We are recruiting a Clinical Research Coordinator, bilingual in Spanish & English, to help us launch a trial of a natural product combinations for early AD intervention. Learn more & apply: bit.ly/McCanceCRC

12/01/2025

This , please consider donating to the McCance Center. An anonymous donor has launched a philanthropic challenge, pledging to match donations - dollar for dollar - up to $20 million! With your gift, you can double your dollar and help make Alzheimer’s disease history. bit.ly/McCanceFund

11/20/2025

Don’t miss our last seminar of 2025! Dr. Nanda Kumar Navalpur Shanmugam, presents Inflammation Beyond the Intestine: Colitis-Induced Immune Changes in Alzheimer’s Mouse Model on December 8th at 11 am. Learn more & register here: https://bit.ly/McCanceEvents

11/18/2025

Tau is a protein found in the brain that serves many functions in healthy brain cells. In Alzheimer’s disease, an abnormal form of tau protein accumulates and creates thread-like structures called neurofibrillary tangles. These clumps prevent tau from doing its job and disrupt normal brain function.

The McCance Center team is working to diagnose and track the disease before symptoms appear. Learn more here: https://bit.ly/Pre-ADI