Laboratory of Cognitive Neurobiology

Laboratory of Cognitive Neurobiology Endeavoring to elucidate the ways in which memory functions in hippocampus and associated cortical areas

The Laboratory of Cognitive Neurobiology is a Boston University lab that is focused on projects seeking to understand the brain circuitry that supports learning and memory. This research is guided by the hypothesis that our ability to remember specific experiences relies on an organization of memories about objects and events in the context in which they occurred. We believe that associations between objects and context is accomplished through the circuitry of the medial temporal lobe. Parallel pathways within the brain represent information about objects, context, and time, and these streams of information converge within the hippocampus. Some current projects include the characterization of how neurons in the medial temporal lobe encode different types of information and how they interact with one another; the exploration of how the prefrontal cortex modulates the retrieval of memories as they bear on ongoing cognitive processes; and the exploration of how hippocampal networks represent information in the spatial and temporal context in which they occur.

Congratulations and to Dr. Kinsky and Dr. Bladon on the successful defense of their theses!
03/15/2019

Congratulations and to Dr. Kinsky and Dr. Bladon on the successful defense of their theses!

New paper out from the lab utilizing calcium imaging in mice to evaluate place field dynamics across long timescales.
11/08/2018

New paper out from the lab utilizing calcium imaging in mice to evaluate place field dynamics across long timescales.

Kinsky et al. demonstrate that hippocampal place fields in mice maintain a stable configuration across long timescales under low attentional demand. Coherent rotations of place fields frequently occurred between sessions, indicating that in some cases instability commonly attributed to global remap...

06/24/2018

Congratulations to current lab member Dr. Ryan Place-Ryan for his successful dissertation defense yesterday.

New publication out this week in Current Biology, evaluating CA1 sequences over multiple timescales. William Mau, David ...
04/27/2018

New publication out this week in Current Biology, evaluating CA1 sequences over multiple timescales.
William Mau, David Sullivan, Nat Kinsky

Episodic memories span timescales of seconds, minutes, and days. Mau et al. use calcium imaging to longitudinally monitor cell sequences in hippocampal CA1. Bayesian decoder analyses show that the same population of neurons carries information about time across all three scales.

Daylong Symposium Celebrates Legacy of Howard Eichenbaum
03/30/2018

Daylong Symposium Celebrates Legacy of Howard Eichenbaum

CAS neuroscientist admired for mentoring, teaching, and leadership

Still coming together at
11/12/2017

Still coming together at

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