MGH Neurology

03/09/2026

The Sean M. Healey & AMG Center for ALS has contracted with Keros Therapeutics, Inc. to design a new Healey ALS MyMatch trial evaluating rinvatercept (KER-065).

Read the press release: https://www.massgeneral.org/neurology/als/news/healey-center-announces-design-with-keros-therapeutics

03/07/2026

Exciting News! The Healey & AMG Center for ALS is assembling its first official team for the Falmouth Road Race under Mass General Brigham for this year’s race on August 16! This is your chance to run one of the most iconic and scenic 7-mile races in the country, along the beautiful Falmouth shoreline, while raising critical funds to advance ALS research at the Healey & AMG Center.

If you're interested in applying to join our in-person team by running on 8/16/26 or joining our team's At-Home Division by completing your 7-miles in the way of your choosing on the course of your choosing, simply email jadimartino@mgb.org with your name, address, and a brief note about why you want to run.

03/06/2026

Launched in 2017 as a collaboration between Mass General and Compassionate Care ALS, the Daniella Lipper ALS House Call Program brings ALS care directly into patients’ homes.

In this new paper, researchers describe the program's feasibility and impact for people living with ALS by minimizing travel burdens and ensuring continuity of care. In the future, the team will expand services and create models for additional similar initiatives.

Read the full paper here: https://onlinelibrary.wiley.com/doi/full/10.1155/nri/6629960/

03/06/2026

View this new research summary for a paper on the first multicenter NIH-funded Expanded Access Protocol (EAP) in ALS. Read about what the researchers did and what they learned from this EAP.

Read the summary here: https://www.canva.com/design/DAHA2YZJr1o/KAbgXY2isugeVXfBSews_g/view

Thank you to the members of our Patient Advisory Committee for their input on this research summary!

03/06/2026

03/04/2026

Next Monday, March 9th, Dr. Suma Babu will present at two sessions at the Muscular Dystrophy Association Clinical and Scientific Conference.

▪️2:00 pm ET: Presenting and chairing “Integrating Research into Multidisciplinary Care for ALS”
▪️4:00 pm ET: Presenting “Healey ALS MyMatch Overview and Updates”

Learn more about the conference here: https://www.mdaconference.org/

03/04/2026

Join us tomorrow, Wednesday, March 4, for our next expert talk!

"PREVAiLS Study: Pridopidine for the Treatment of ALS" presented by Nils Confer, PhD - Executive Medical Director of Prilenia Therapeutics and Sabrina Paganoni, MD - Co-Director, MGH Neurological Clinical Research Insistute.

🗓️ Wednesday, March 4, 2026
⏱️ 7:00 pm ET / 4:00 pm PT
📝 register at: https://www.everythingals.org/events
💻 virtual, on zoom

We hope to see you there for this exciting update from Prelenia Therapeutics!

03/02/2026

To learn about the enrollment status of trial sites in the HEALEY ALS Platform Trial, please visit our website: https://www.massgeneral.org/neurology/als/research/platform-trial-sites

02/26/2026

The Healey & AMG Center for ALS is pleased to announce that the first participant has been enrolled in Regimen I of the HEALEY ALS Platform Trial evaluating NUZ-001 by Neurizon Therapeutics.

Read the press release here: https://www.massgeneral.org/neurology/als/news/first-participant-enrolled-regimen-i-healey-als-platform-trial-nuz-001

02/23/2026

In this new paper, Healey & AMG Center team members and collaborators studied the effects of the ALS SOD1 gene mutation on impaired nucleocytoplasmic transport (NCT). When NCT is impaired, the movement of molecules in and out of the nucleus is disrupted, leading to damage. The researchers' findings support targeting NCT disruption for future therapeutic strategies.

Read the full paper: https://link.springer.com/article/10.1186/s13024-026-00930-8

Impaired nucleocytoplasmic transport (NCT) has emerged as a shared pathogenic mechanism in various neurodegenerative disorders, including amyotrophic later

02/23/2026

Please join us on Thursday, 2/26, at 5:00 pm ET for a community Q&A webinar. This week, Drs. James Berry and Jenny Wang of Massachusetts General Hospital will lead a discussion on Neurofilament Light Chain (NfL) analysis in ALS research and how it applies to the HEALEY ALS Platform Trial.

Register:
https://mgb-org.zoom.us/webinar/register/WN_JW9rQBhTRFW5uoUIDtJguw #/registration



Northeast ALS Consortium (NEALS) ALS ONE I AM ALS EverythingALS Les Turner ALS Foundation Muscular Dystrophy Association ALS TDI The ALS Association

02/20/2026

The Healey & AMG Center for ALS recently sent out their winter newsletter. Check it out to learn more about research, publications, announcements, and more.

Read more here: https://conta.cc/3ObE2Ml

Email from Massachusetts General Hospital Winter 2026 Newsletter   Sean M. Healey & AMG Center for ALS Winter 2026 Newsletter View our website   Dear friends, Thanks to your unwavering support, 2025 w