BioLife Solutions, Inc.

01/29/2026

Are you hearing more about Transient Warming Events in the Cell and Gene Therapy ecosystem?

♨️ A Transient Warming Event (TWE) occurs when a cryopreserved sample is exposed to warmer-than-intended temperatures for any period of time, including the time it takes to remove a sample from the freezer. A temperature excursion like this might seem insignificant at first, but even brief exposure to higher temperatures can compromise the integrity of the frozen cells post-thaw.

♨️ In the latest Cytotherapy journal, Canadian Blood Services and Robert Ben of Panthera CryoSolutions (part of BioLife Solutions), explore TWEs and how different cryosolutions can impact stem cell grafts.

♨️ The study identifies ice recrystallization during warming as a dominant mechanism of cryoinjury and shows that the addition of ice recrystallization inhibitors (IRI) can effectively mitigate TWE-induced damage.

📑Read on: https://www.isct-cytotherapy.org/article/S1465-3249(25)00903-X/abstract

01/28/2026

The cryopreservation success of cell-based materials may be limited by ice recrystallization, a major and under-represented source of cryoinjury. 💥

How can you address ice recrystallization?

🔎 In a November 2025 feature with Engineering & Biotechnology News, the Panthera CryoSolutions (part of BioLife Solutions) team, shared a tutorial on ice recrystallization inhibitor (IRI) technology.

❄️ Synthetic IRIs, developed to mimic antifreeze protein activity without associated toxicity or ice-shaping artifacts, can prevent ice crystal growth.

❄️ Data across multiple cell types and tissues show that incorporating IRIs into cryopreservation processes can improve post-thaw viability, functional recovery, and resilience to temperature excursions.

Review the tutorial below to learn about the science behind IRIs, and why you should consider incorporating them into your existing biopreservation workflow. 👇

https://www.genengnews.com/topics/translational-medicine/targeting-ice-recrystallization-to-improve-cryopreservation-consistency/

01/22/2026

Are you ready for a new Phacilitate Advanced Therapies Week experience? 😎🏖️

Join us on February 9-12 in one of the fastest growing biotech hubs – San Diego, CA. The BioLife team will be onsite at booth 420. You must check out our NEW booth display, literature, and swag! 🙌

Come say hi to meet us for the first time or to catch up. We’re here to help you with biopreservation best practices, scaling up, CGT manufacturing challenges, and staying ahead of regulations.

This year’s agenda includes a new Investment Summit, Networking Concierge service, and more opportunities to connect than ever before!

➡️ Register soon: https://www.phacilitate.com/advanced-therapies-week

🧪 Are you a therapeutic/drug developer with an active clinical or pre-clinical pipeline? Request a FREE pass here: https://ow.ly/FAoJ50XSLxv

01/21/2026

As we mentioned yesterday, BioLife Solutions is proud to sponsor the ScaleReady G-Rex Grant Tour, which supports the Emily Whitehead Foundation.

If you are attending the Houston, TX kick-off event today (January 21), please make sure to visit the BioLife table. You’ll find Newton and Selley onsite and ready to meet you.

BioLife is providing product support and discounted access to tools and services for G-Rex Grant recipients to reduce development barriers. 🔬

Ask for the BioLife-ScaleReady flyer at our table! ✅

🚀 View details and the agenda: https://www.scaleready.com/concepts/g-rex-grant-tour-houston/

01/20/2026

We’re pleased to announce our partnership with ScaleReady and the Emily Whitehead Foundation to sponsor the G-Rex® Grant Tour, a year-long, 12-city initiative launching tomorrow, January 21, in Houston, TX. 🤝

The tour is designed to advance cell and gene therapy (CGT) manufacturing by delivering educational discussions, technical expertise, and scalable tools directly to researchers and developers across major U.S. CGT hubs. 🔬

We’re also thrilled that ScaleReady will support BioLife’s new Aby J. Mathew Center for Biopreservation Excellence by providing G-Rex® consumables, materials, and expertise to support process optimization and scale-up for clients.

📍Check out our latest news to find out more about the tour: https://www.biolifesolutions.com/resource-center/insights-blog/advancing-cell-gene-therapy-manufacturing-collaboration/

01/16/2026

🗨️ While we’re on the subject of closed-systems and processing this week, are you familiar with the CellSeal® Connect?

This is a closed-vial for aseptic filling and retrieval developed specifically for cell and gene therapy manufacturing.

The CellSeal Connect makes your intermediate reagent transfers seamless and sterile with weldable fill & retrieval and vent lines.

👀 Want to see how the Connect works? What our new “How-to” video below.
https://youtu.be/CmxJFN4jgos

♾️ Find out more about the CellSeal Connect: https://www.biolifesolutions.com/handling/cellseal-connect-vials/

This step-by-step tutorial demonstrates how to properly fill, seal, store, and retrieve material using the CellSeal® Connect closed-system vial. Chapters:0:0...

01/14/2026

What can closed systems do for you?

Closed-system processing and closed cryogenic storage in cell and gene therapy manufacturing can provide scalability, a reduction in batch failures, operational efficiencies, contamination resistance, and other cost reductions, all while maintaining cell viability. ✅

To look at the data and case studies behind this, check out our latest Cell & Gene Therapy Insights article. It contains contributions from Erik Woods (Ossium Health), Jon Pileggi (CTMC), and Sean Werner (BioLife Solutions).

🔎 https://www.insights.bio/cell-and-gene-therapy-insights/journal/article/3701/closedsystem-process-optimization-for-cgt-manufacturing-and-storage

Don’t have time to read through it? Watch the on-demand webinar where this conversation first started:
🖥️ https://www.insights.bio/cell-and-gene-therapy-insights/webinars/757/closing-the-loop-eliminating-open-handling-risks-in-cgt-manufacturing

01/12/2026

BioLife Solutions Announces Preliminary Fourth Quarter and Full Year 2025 Unaudited Revenue from Continuing Operations

Read the press release for details.

https://investors.biolifesolutions.com/2026-01-12-BioLife-Solutions-Announces-Preliminary-Fourth-Quarter-and-Full-Year-2025-Unaudited-Revenue-from-Continuing-Operations

01/09/2026

📣 Did you hear? Phacilitate Advanced Therapies Week 2026 is being held on February 9-12 instead of in January, and in San Diego instead of in Miami this year.

Come connect with the BioLife team at booth 420 – Todd Berard, Sandy Jones, Bill Yang, Vicky Tran, Andrew Sabatier, and Amy Ma will be onsite. We can’t wait for you to see our new booth display.

We’re here to catch up and discuss your biopreservation and cell processing successes and challenges.

Make your plans to America’s Finest City soon! ☀️🌊🦭

https://www.phacilitate.com/advanced-therapies-week

Are you a therapeutic/drug developer with an active clinical or pre-clinical pipeline? Request a FREE pass here:
https://forms.reg.buzz/advanced-therapies-week-2026/?exhibitor-inviter=biolife-solutions&badge-type=ad0f5158-2cda-11f0-a526-000000000000×tamp=1796929689&signature=NjUwODY3ZWNhZDFkYmRiOWE3OWY2ZDk0MDY1MzNiYmQ3NzQ3MDIwZQ%3D%3D

12/31/2025

We’d like to wish all our customers, suppliers, investors, and team members a Happy New Year! 🎆

We are grateful for your dedication, efforts, and passion to move the advanced therapies field forward.

Here’s to an amazing and prosperous 2026! ✨👏

12/29/2025

We’re thrilled to announce we are sponsoring and exhibiting at Phacilitate Advanced Therapies Week 2026 in the beautiful, warm, and sunny city of San Diego, CA. ☀️🏝️

Join us at booth 420 to see how we can work together to optimize your workflow.

Let’s talk about your biopreservation media and reagents, storage containers, fill & finish systems, and your thawing procedure. We have unique technologies to preserve and save your cells.

Don’t miss out on this innovative cell and gene therapy event!

👉 Learn more and register soon:
https://www.phacilitate.com/advanced-therapies-week

🎯 Are you a therapeutic/drug developer with an active clinical or pre-clinical pipeline?
Request your free pass here:
https://forms.reg.buzz/advanced-therapies-week-2026/?exhibitor-inviter=biolife-solutions&badge-type=ad0f5158-2cda-11f0-a526-000000000000×tamp=1796929689&signature=NjUwODY3ZWNhZDFkYmRiOWE3OWY2ZDk0MDY1MzNiYmQ3NzQ3MDIwZQ%3D%3D

12/26/2025

As 2025 wraps up, we’d like to share our last three blog posts if you’re in need of some ‘quiet reading time’ after all the holiday events.

🔥 September: The Silent Threat in Cell Therapy Development: Transient Warming Events

🧪 October: Biopreservation Is Critical. Start with the Team That Wrote the Playbook.

🤝 November: Preserving the Promise™—Together

Check them out and let us know what you think:

BioLife Solutions Insights