11/10/2025
Is There a Difference Between Ketamine and Esketamine (Spravato) for Depression?
The discovery of ketamine’s and esketamine’s rapid antidepressant effects has been called the greatest breakthrough for depression research in the last 60 years. There is a big debate about whether there is a significant clinical difference between the two forms: racemic ketamine (used off-label for depression) in an intravenous (IV) or intramuscular (IM) and esketamine (an FDA-approved nasal spray, Spravato).
Full Story - https://hopeforyourbrain.com/clinic-news/is-there-a-difference-between-ketamine-and-esketamine-spravato-for-depression/
Synaptic Psych
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