12/30/2025
📢 New Research on Preventing Recurrent UTIs in Older Women 🧪🩺
We want to share an important new study that looked at how to help reduce recurrent urinary tract infections (rUTIs) — a common and often frustrating condition, especially in older women.
🔬 What was studied?
Researchers conducted a randomized, placebo-controlled clinical trial to see whether methenamine hippurate, a non-antibiotic antiseptic, can help prevent UTIs from coming back in women aged 70 and older who experience frequent infections. 
📈 Key Findings:
✔️ Women taking methenamine hippurate had fewer UTI antibiotic treatments during the 6-month treatment period compared with those taking placebo. 
✔️ After stopping the treatment, UTI treatments were more frequent in the methenamine group during the follow-up, suggesting that benefits may decrease after stopping the medicine. 
✔️ There were no major differences in UTI symptom severity, duration, or complications between groups. 
💡 Why this matters:
• Antibiotic resistance is a growing concern, especially when antibiotics are used repeatedly. 
• Methenamine hippurate may be a useful antibiotic-sparing option for long-term UTI prevention. 
• Discussions with your clinician can help determine whether this option might be appropriate for you or someone you care for.
📌 Takeaway for Patients:
If you or a loved one struggles with frequent UTIs, it’s worth talking with your healthcare provider about all prevention strategies — including the potential role of non-antibiotic options like methenamine hippurate.
🧬 Study Source: Clinical Microbiology and Infection (2025). 
