02/25/2026
What Are Allergy Drops?
They are drops of offending allergen, food or airborne, placed under the tongue, creating allergen tolerance.
How Do They Work?
Receptors under the tongue called Langerhans Giant Cells take up and partially digest protein molecules in the allergy drop solution and present them to immune system T cells. These T-regulatory cells induce ALLERgen TOLerance. They do this by training the immune system by a process called “down regulation”. Each time an allergy drop is placed under the tongue, the immune system becomes more tolerant. This results in significant symptom reduction and less need for medications and procedures.
Safe, Painless, Effective, Low Cost, High Compliance
Allergy drops are administered at home, saving time and travel expense. The out of pocket cost is low, especially considering less need for medications and doctor trips. Allergy drop therapy has been safely administered in the U.S. and in Europe. A literature review by Southwestern Medical School in Dallas revealed no severe life-threatening reactions in 15 consecutive years of allergy drop therapy worldwide. Self limiting adverse reactions have been reported in less than 3 in 1000 doses. Studies have shown that the development of asthma is many times less likely to develop in children that receive allergy drop therapy. Because allergy drops are painless, they are an ideal allergy solution for children and infants. Long-term compliance is as high as 95%.
There are, several factors that make allergy drops a viable alternative to shots, as recommended by the World Health Organization and the Cochrane Study Group out of London.
How is testing done?
Sublingual testing is done by simply placing drops of suspected food proteins under the tongue several times a day, and observing symptom changes.
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