10/31/2025
Just Move
Perhaps you have heard it before, perhaps not; Exercise is Medicine. Sure, exercise has many benefits, but movement is life, compared to constant rest. And the reason that moving is better than rest might surprise you.
I’m not here to tell you to go and exercise. We all know it will be good for you, but I want you to think a little differently about it. Rather than tell you that exercise is medicine, I want you to know that movement is medicine too. You might not know it, but the contraction of muscle, even at low intensity, even for short periods of time, is beneficial.
Let me tell you why. Now, going back into high school biology you learned about a tiny structure inside almost every cell called the mitochondria. These tiny structures make ATP, and ATP is life. In fact, if you run out of the ability to make ATP, you are dead. Get your attention yet?
On an extremely simple level activity forces muscles to contract and that prompts three processes. First calcium is pumped into the muscle so they can contract by taking the ATP made by the mitochondria. Then, as your muscle relaxes it pumps in magnesium, all the time depleting ATP. This process sets off a bunch of signaling pathways that force the cell to process glucose (blood sugar), and fat to make more ATP to keep you energized and moving. That action alone forces the body to absorb more glucose (sugar) from the blood, even without using insulin.
Why is that important? Because chronically elevated blood sugars cause inflammation. And chronic inflammation causes your body to produce more free radicals which ultimately oxidize cholesterol and promote plaque buildup. In addition, chronic inflammation has been found at the root of all disease. Did you catch the word all?
So keeping your inflammation down by keeping your blood sugar down is pretty important to being healthy.
That’s not all that happens of course. Because right in the middle of all this energy making, the body takes a key protein called AMPK, which acts as an energy sensor for ATP. As the ATP is used up, it stimulates something called PGC-1a, which is considered the master regulator of your metabolism. Yep, this PGC-1a increases your ability to burn fat, take sugar from your blood, and make more mitochondria.
A quick lesson on aging. As you age, especially if you are not active, and especially if you do not strength train, you lose 5-7 pounds of lean muscle per decade of life. This process generally starts around 35 years of age; and accelerates after 50. Along with that muscle loss (called sarcopenia), we lose the life-giving mitochondria. Add into the mix bad food choices (causing more inflammation and more free radical formation) and we have a recipe for rapid aging and increased risk of disease.
Now, back to PGC-1a. Activating it also activates the production of more mitochondria. If we exercise more, we also activate the mechanism that kills off bad cells and replaces them with fresh new ones, it’s called autophagy.
This whole process renews the mitochondria keeping your free radical production under control and your inflammation in check.
Did not know that activating muscles also activates proteins called myokines which actually control inflammation and stimulate the production of irisin, a myokine that tells your cells to burn fat, but only if you move.
Now, while some people exercise for an hour a few times a week to produce all the lasting effects of metabolic health, some of them go and sit behind a desk all day long, effectively undoing the good they have done. Muscle contraction, even on a low level, is paramount to your metabolic health. It keeps those blood sugars low (without the need for extra insulin) and keeps your inflammation under control (as long as you avoid too much sugar and processed carbohydrates).
So, movement is medicine. And yes, exercise does more for you, but constant movement is far better than inactivity, which increases inflammation and speeds muscle loss.
You do still need to keep your strength up though. After 50 you lose it rapidly without strength training, and by 75 your strength literally equals about half of what you had at 30. Don’t let that happen to you. Stay strong with your exercise and move more during the day. Muscle contraction is the deciding factor for keeping your body detoxed, removing excess sugar from your blood, building more mitochondria, and keeping disease at bay.
The average body is probably built to last at least 100 years. But what we do to it in that time, how we treat it, actually determines how long it lasts. It’s not so much that we die as it is that we kill ourselves with the lifestyle we chose to follow. Choose wisely, live a life of health.