03/07/2026
For decades, Lyme disease has been treated as if it were caused by a single bacteria and diagnosed with a limited set of tests. But the science is showing us something far more complex.
In this powerful Tick Boot Camp interview, we speak with Dr. Bobbi S. Pritt of Mayo Clinic—one of the world’s leading experts in tick-borne diseases and a scientist who has helped expand our understanding of the pathogens ticks carry.
Dr. Pritt personally led the discovery and description of two previously unknown human pathogens: Borrelia mayonii, a newly recognized cause of Lyme disease in the United States, and Ehrlichia muris eauclairensis, another tick-borne infection identified in the Upper Midwest. These discoveries changed the scientific understanding of tick-borne disease and revealed that ticks can transmit more pathogens than many people realize.
During our conversation, Dr. Pritt walks us through the science of Lyme diagnostics and why testing can be challenging—especially early in infection. She explains the differences between antibody testing and PCR testing, why timing matters, and how emerging technologies like metagenomic sequencing may soon allow scientists to detect multiple pathogens from a single sample.
We also explore how different tick species behave, how co-infections complicate diagnosis, and why researchers continue to discover new tick-borne pathogens as science advances and surveillance improves.
For anyone living with Lyme disease, struggling with unexplained symptoms, or trying to understand the rapidly evolving science of tick-borne illness, this episode offers rare insight from one of the researchers helping shape the future of diagnostics and discovery.
Tune in to hear the full conversation with Dr. Bobbi S. Pritt on the Tick Boot Camp Podcast. Listen now at TickBootCamp.com or wherever you get your podcasts.