Onpharma Company

Onpharma Company Onpharma's Onset EZ Pen is the easy choice for buffering. The Onset System is simple to use and allows the clinician to inject and go right to work.

Onpharma's Onset is a revolutionary buffering system that uses Sodium Bicarbonate to raise the pH level of local anesthetic. Onset makes your local anesthetic reliable, predictable and more comfortable for the patient.

Looks like is on the up and up!
11/06/2025

Looks like is on the up and up!

Three companies are vying to be the best-in-class anesthetic, but the ultimate winner may be dental patients.

📣 Join Craig at the NDA CE event this week! Try with the Onset EZ Pen 💥➡ LEARN MORE: https://www.ndaonline.org/
11/04/2025

📣 Join Craig at the NDA CE event this week! Try with the Onset EZ Pen 💥

➡ LEARN MORE: https://www.ndaonline.org/

📣 Calling all Buffalo area dental professionals! Join us at the Buffalo Niagara Dental Meeting next week to see how easy...
10/30/2025

📣 Calling all Buffalo area dental professionals! Join us at the Buffalo Niagara Dental Meeting next week to see how easy it is to buffer your with the new Onset EZ Pen! Visit us at booth #115 to try it!

➡ http://bndmeeting.com/

Join the Onset EZ team at booth #38 at this upcoming event!
10/27/2025

Join the Onset EZ team at booth #38 at this upcoming event!

We’re just ONE MONTH away from the 2025 NNOHA Annual Conference! ⏳ Register by October 19 to take advantage of standard conference pricing before rates increase.

Join your colleagues November 9–12 in the heart of San Antonio, TX. These four days of world-class continuing education are specifically developed for safety-net oral health professionals. Connect with like-minded providers, learn from expert clinical and practice management presenters, and be motivated by inspiring plenary speakers!

This year’s theme, These Are My People, celebrates the strength we build through connection and shared purpose.

➡️ Register here: https://bit.ly/nnoha2025conference

10/16/2025

We agree! Thank you for the 💯 review! 👏

10/10/2025

It takes only seconds to buffer with the Onset EZ Pen. Experience the difference and see how your can improve !

Address

123 West Nye Lane, Suite 723
Carson City, NV
89706

Opening Hours

Monday 9am - 5pm
Tuesday 7am - 5pm
Wednesday 7am - 5pm
Thursday 7am - 5pm
Friday 7am - 2pm

Telephone

+18773366738

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Onset Buffering System

Chair side buffering using the Onset system is simple to incorporate, easy to use, and will make your local anesthetic better whether you are using Articaine, Lidocaine, Priolocaine or Mepivicaine.

Because local anesthetic is a key part of so many procedures in the dental office, a long-standing question among dental practitioners has been: How can we make our local anesthetic better? Chemistry lies at the heart of the answer. Local anesthetics begin as alkaline solutions, but manufacturers add hydrochloric acid to lower the pH to around 3.5 (or the same as lemon juice) in order to deliver a multi-year shelf life. However, a long-settled principal of parenteral injections is that an injection should be delivered at a pH as close as possible to the pH of the human body, approximately 7.4.

Onpharma gives dentists their first practical way to buffer the local anesthetic cartridge at chair side toward physiologic pH so practitioners no longer have to deliver an injection having the pH of lemon juice.