Onpharma Company

Onpharma Company Onpharma's Onset EZ Pen is the easy choice for buffering. The Onset System is simple to use and allows the clinician to inject and go right to work.

Onpharma's Onset is a revolutionary buffering system that uses Sodium Bicarbonate to raise the pH level of local anesthetic. Onset makes your local anesthetic reliable, predictable and more comfortable for the patient.

📣 Don't miss these courses today and tomorrow at the Congress!
01/30/2026

📣 Don't miss these courses today and tomorrow at the Congress!

01/28/2026

How EZ is it to buffer with Onset EZ?

📣 🦷 Don't miss team at these upcoming events! Try your with the EZ Pen and experience the difference!
01/21/2026

📣 🦷 Don't miss team at these upcoming events! Try your with the EZ Pen and experience the difference!

01/13/2026
🦷 Built for efficiency, the Onset EZ Pen provides fast and easy buffering in seconds with no training needed. Each Onset...
01/09/2026

🦷 Built for efficiency, the Onset EZ Pen provides fast and easy buffering in seconds with no training needed. Each Onset EZ Pen delivers 30 buffering doses without extra packaging or Sharps waste and may be used over 30 days after opening. Convenient and easy to use, one (1) Onset EZ Pen per operatory is recommended.
➡ https://www.onpharma.com/products/onset-ez-local-anesthetic-buffering-device

📣 Calling all Colorado dental professionals! Join us at the Rocky Mountain Dental Conference to experience the differenc...
01/05/2026

📣 Calling all Colorado dental professionals! Join us at the Rocky Mountain Dental Conference to experience the difference of Onset EZ!
➡ https://rmdconline.com/

THIS! ⬇️
12/26/2025

THIS! ⬇️

Address

123 West Nye Lane, Suite 723
Carson City, NV
89706

Opening Hours

Monday 9am - 5pm
Tuesday 7am - 5pm
Wednesday 7am - 5pm
Thursday 7am - 5pm
Friday 7am - 2pm

Telephone

+18773366738

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Onset Buffering System

Chair side buffering using the Onset system is simple to incorporate, easy to use, and will make your local anesthetic better whether you are using Articaine, Lidocaine, Priolocaine or Mepivicaine.

Because local anesthetic is a key part of so many procedures in the dental office, a long-standing question among dental practitioners has been: How can we make our local anesthetic better? Chemistry lies at the heart of the answer. Local anesthetics begin as alkaline solutions, but manufacturers add hydrochloric acid to lower the pH to around 3.5 (or the same as lemon juice) in order to deliver a multi-year shelf life. However, a long-settled principal of parenteral injections is that an injection should be delivered at a pH as close as possible to the pH of the human body, approximately 7.4.

Onpharma gives dentists their first practical way to buffer the local anesthetic cartridge at chair side toward physiologic pH so practitioners no longer have to deliver an injection having the pH of lemon juice.