04/22/2026
Do you experience chronic stress, even when things are going well? Is ADHD a major influence in your life? Are you dealing with estrogen dominance despite maintaining a healthy lifestyle? Your genes might be to blame. A fast or slow COMT gene mutation can impact your mental health and stress response. The positive news is that lifestyle changes can offer hope.
The COMT gene plays a crucial role in how our bodies manage key brain chemicals like dopamine, epinephrine, norepinephrine, and estrogen. Variations in this gene affect the activity of the catechol-O-methyltransferase enzyme, which breaks down these substances so the body can eliminate them efficiently. These differences can influence how people respond to stress, their cognitive abilities, and their risk for conditions such as anxiety, ADHD, and schizophrenia. Understanding these variations helps explain why some people handle stress better or worse than others and why mental health symptoms can vary widely.
If you think you might have a COMT gene mutation, it's crucial to consult your healthcare provider and undergo appropriate testing. Once confirmed, there are numerous steps you can take to improve your well-being and manage your health effectively.
To schedule with Pro Health Functional Medicine contact our Chandler, AZ office at 480.306.4372 or visit us online
These differences can influence how people respond to stress, their cognitive abilities, and their risk for conditions such as anxiety, ADHD, and schizophrenia. Understanding these variations helps explain why some people handle stress better or worse than others and why mental health symptoms can v...