12/23/2025
This question often comes up all the time..
Should I use systemic estrogen with vaginal estrogen?
If you are using systemic estrogen, you will also need vaginal estrogen. Even if you decide not to use systemic estrogen you should consider at least using vaginal estrogen. They work differently.
Systemic hormone therapy treats vulvovaginal atrophy less effectively than vaginal hormone therapies
Vaginal estrogen is the preferred hormonal approach for GSM-associated symptoms. it treats vulvovaginal atrophy and pain with s*x while maintaining primarily local effects.
If you’re in midlife and want to learn more about this transition, this page is for you. Follow me for expert guidance!
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