Main Street Drug

Main Street Drug We are an independent pharmacy offering quick and accurate service in Charles City, Iowa. We also deliver to surrounding areas and towns.

12/17/2025

All holiday decorations are 25% off now through the end of the year!

Fight the flu and protect yourself and others by getting vaccinated this year. If you haven't received your annual flu s...
12/17/2025

Fight the flu and protect yourself and others by getting vaccinated this year. If you haven't received your annual flu shot yet, now's the time! Stop by the pharmacy today.

12/16/2025

Please note our upcoming holiday hours. We will be closing at noon on Christmas and New Years eve. We will be closed on Christmas and New Years day. Happy holidays from all of the Main Street Drug team!

When you're not feeling well, the last thing you want to do is stand in the cough and cold aisle trying to decide which ...
12/16/2025

When you're not feeling well, the last thing you want to do is stand in the cough and cold aisle trying to decide which over-the-counter option you should purchase. Here's how a pharmacist can help simplify the process for you and be your OTC ally. We're always here to help! Speak with us to learn more the next time you're in the pharmacy.

12/15/2025

Wishing all of our customers a very happy Holiday season! We are thankful for each and every one of you during this season and always. Please take note of our upcoming holiday hours as time approaches.

December 24 closing at noon.
December 25 closed
December 31 closing at noon.
January 1st closed

Your body needs vitamin D to help absorb calcium, build strong bones, and strengthen your immune system to fight off inf...
12/13/2025

Your body needs vitamin D to help absorb calcium, build strong bones, and strengthen your immune system to fight off infectious bacteria and viruses. Here are the four main sources to know.

12/11/2025

Have you gotten your flu shot yet? The flu vaccine prevents tens of thousands of hospitalizations each year. Protect yourself and the ones you care for by getting your annual flu shot. Stop by the pharmacy today.

12/09/2025

During cold and flu season, a type of pneumonia known as walking pneumonia also becomes more common. Here's what parents should know about this respiratory illness, including what symptoms to watch for and how to prevent it from spreading.

This winter, we're here to help you and your family get through cold and flu season without stopping or slowing down. Sp...
12/05/2025

This winter, we're here to help you and your family get through cold and flu season without stopping or slowing down. Speak with our pharmacist the next time you pick up your prescriptions to learn more about how we can help.

Medicare Part D Open Enrollment for 2026 is happening now. Following these steps can help you choose the best plan that ...
12/05/2025

Medicare Part D Open Enrollment for 2026 is happening now. Following these steps can help you choose the best plan that fits your needs. Learn more: https://bit.ly/2mCNrQd

12/04/2025

If you’re at high risk for complications from the flu, a flu shot is an opportunity to protect yourself. We make the process of getting your annual vaccine easy and convenient so that you can stay safe all season. Contact us to learn more!

Between lowering temps and the busyness of the holiday season, you may find that you're starting to feel under the weath...
12/01/2025

Between lowering temps and the busyness of the holiday season, you may find that you're starting to feel under the weather, and turn to over-the-counter cold and flu remedies. But you may notice they have some less-than-pleasant side effects. Learn more about how to avoid them so you can get back to feeling better.

Address

204 Main Street
Charles City, IA
50616

Opening Hours

Monday 9am - 5:30pm
Tuesday 9am - 5:30pm
Wednesday 9am - 5:30pm
Thursday 9am - 5:30pm
Friday 9am - 5:30pm
Saturday 9am - 12pm

Telephone

+16412283519

Website

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