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Lighthouse Instruments

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United States
Charlottesville, VA
Lighthouse Instruments

Solutions for Container Closure Integrity testing, Oxygen monitoring, Moisture determination and Media fill inspection.

LIGHTHOUSE offers complete solutions for headspace Oxygen Monitoring, Container Closure Integrity Testing, Moisture Determination and Microbial Contamination inspection of media vials. Our solutions include feasibility studies, process and packaging studies, method development, method validation protocols, automated or benchtop lease platforms, on-site trouble shooting and support. Rapid, nondestr

uctive, laser-based headspace analysis is suitable for applications specific to the sterile pharmaceutical industry. It is a useful analytical tool to generate statistical process and product data in all stages of the product life cycle, from Development to Manufacturing and Quality Control. LIGHTHOUSE Instruments is the leading provider and manufacturer of headspace analysis platforms and measurement services. Contact us for a free demo, feasibility study, or other information.

04/22/2026

📍 We’re in Florence. Day 1 of the PDA Italy Chapter: Excellence on Manufacturing Process: From API to Filling.

Great discussions today with our experts Dr. Francesca Caprioli and Giovanni Auricchio, PhD, MBA on the role of headspace analysis across the pharmaceutical landscape.

🎤 Highlight of the day: “Integrating CCI Testing into a Robust GMP Control Strategy: Industry Case Study”. Presented by Dr. Francesca Caprioli and Alessia Pacioni (PolPharma Biologics).

04/20/2026

EU GMP Annex 1 reinforces the need for risk-based, science-driven CCI strategies.

A flexible and scalable CCI program can address regulatory and manufacturing concerns while mitigating risk to the product, the business, and, most importantly, the patient.

📘 Get our program for CCI testing and Annex 1 compliance: https://lighthouseinstruments.com/knowledge-center/flyer-compliance-program-for-eu-annex-1-container-closure-requirements/

04/14/2026

Last week in Amsterdam, we hosted a fun and relaxed evening with our team.

It was all about good company, drinks 🍹, and a touch of creativity 🎨.

We set up a small artistic corner where everyone could create something unique.

Our canvas for the evening? Tiles, an unexpected choice that sparked plenty of imagination.

It was great to see everyone getting creative, sharing ideas, and enjoying the moment together ✨

04/07/2026

⚡ High-Voltage Leak Testing vs Headspace Gas Analysis

High-voltage leak testing (HVLD) has some important limitations.

• Only works with liquid-filled containers
• Requires electrically conductive products
• Cannot test dry or frozen products
• May risk damaging the sample

Gas-based headspace analysis, on the other hand, is non-destructive and works with liquid, dry, and lyophilized products across different container formats.

Want to learn more about CCIT methods?

Explore our Knowledge Center for more insights https://lighthouseinstruments.com/domain/container-closure-integrity-testing/

04/01/2026

Join us on for a practical and holistic webinar where we will explore how to design, qualify, and implement effective CCI assurance strategies.

📅 Apr 16, 2026 3:30 PM CEST

What you will learn:
▪️ How to design packaging development studies that enable CCI assurance
▪️ How to structure production line CCI qualification studies using a science-based approach
▪️ How to apply headspace CCIT methods for all sterile pharmaceutical products
▪️ How to implement CCIT strategies compliant with USP
How to select appropriate CCIT methods based on product type, packaging configuration, and risk profile

🎤 Speaker
Dr. Francesca Caprioli
Laboratory Director, Lighthouse Instruments

Registrations here 👉 https://lnkd.in/e-JN7kRg

03/23/2026

The best Container Closure Integrity Testing (CCIT) method depends on several factors:

• Container type
• Product sensitivity
• Regulatory requirements

In many cases, headspace analysis is preferred because it is non-destructive and highly versatile across different container formats.

📚 Learn more about CCIT methods
👉https://lighthouseinstruments.com/domain/container-closure-integrity-testing/

03/16/2026

As CCI testing programs mature, consistency and scalability become essential.

Controlled sample conditioning supports reproducible headspace gas ingress testing while maintaining flexibility across container formats and product stages.

📄 Learn more about the new LIGHTHOUSE control module for CCI testing. The flyer is available herehttps://lighthouseinstruments.com/wp-content/uploads/2026/03/CCIT-Vessel-Control-Module-flyer_V1_.pdf

03/10/2026

📅 Join us at INTERPHEX Global 2026 | New York
📍 April 21 to 23, 2026
📍 Booth 1853 | Javits Center, NYC

Come and explore the latest advancements in:
▪️ Container Closure Integrity (CCI) Testing
▪️Lyophilized Moisture Determination
▪️Automated Media Fill Inspection

What you can experience at our booth
▶ Live Demonstrations
See our automation system live and discover how automated headspace analysis can improve efficiency, reliability, and throughput in pharmaceutical manufacturing.

▶ Expert Insights
Meet our specialists Tom Millner, Rick McDougal and Jay Rowden and learn how our technologies can support your quality control, process monitoring, and compliance goals.

🎁 Exclusive Giveaway
Visit our booth for a chance to win a brand new iPad.

🤝Schedule a meeting with our team in advance and make the most of your visit https://lnkd.in/dyZyzagB

We look forward to seeing you in New York at INTERPHEX 2026!

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03/09/2026

📅 Save the Date | ISPE Aseptic Conference – Washington, D.C., USA

We will be attending the 2026 ISPE Aseptic Conference on March 23–24 in Washington, D.C.

Our expert Rick McDougal will be at Booth 412, looking forward to meeting you and discussing how LIGHTHOUSE headspace analysis solutions support aseptic manufacturing, process monitoring, and quality assurance.

If you are attending, make sure to stop by.

See you in D.C. !

03/03/2026

Autoinjectors present unique challenges for container closure integrity testing. In this case study, a non-destructive headspace gas ingress method was developed to evaluate a fully assembled autoinjector, aligned with USP guidance.

📘 Read the case study on CCI method development for autoinjectors https://lighthouseinstruments.com/knowledge-center/container-closure-integrity-cci-test-method-development-for-autoinjectors-with-an-optically-transparent-window/

02/24/2026

📅 Save the Date – PDA Week 2026

We will be at PDA - Parenteral Drug Association Week 2026 in Denver, Colorado, from March 22 to 27, 2026.

Our experts Jay Rowden and Tom Millner are looking forward to meeting you at our booth 205 to discuss how our headspace analysis solutions and how they support your manufacturing process.

See you in Denver !

02/23/2026

📅 Save the Date | PharmaTechnica, Wiesbaden, Germany

We will be attending PharmaTechnica | PharmaCongress on 24 and 25 March 2026 in Wiesbaden, Germany.

Join our experts Dr. Marnix Wieffer and Avand Amedi at booth C22 to discuss the latest innovations and solutions from Lighthouse Instruments.

For your convenience, feel free to schedule a meeting with our team in advance 👉 https://lnkd.in/e6Cj4aG7

We look forward to seeing you there.

Address

2050 Avon Court
Charlottesville, VA
VA22902

Opening Hours

Monday	9am - 5pm
Tuesday	9am - 5pm
Wednesday	9am - 5pm
Thursday	9am - 5pm
Friday	9am - 5pm

Telephone

+31207051050

Website

https://lighthouseinstruments.com/

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