The James Clinic

The James Clinic Medicine without the noise. Integrative concierge clinic helping complex patients live healthier, longer. Virtual nationwide and locations in Missouri and Iowa.
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You can’t see inflammation, but you can feel it.It’s the fatigue that won’t lift.The brain fog that clouds your focus.Th...
11/13/2025

You can’t see inflammation, but you can feel it.
It’s the fatigue that won’t lift.
The brain fog that clouds your focus.
The stubborn weight that won’t move, no matter what you eat.

Inflammation isn’t always an enemy, it’s your body’s built-in healing response.
But when that response never shuts off, it quietly drives disease:
▪️ Autoimmunity
▪️ Digestive issues
▪️ Hormone imbalances
▪️ Cardiometabolic conditions
▪️ Chronic pain

In functional medicine, we don’t just suppress inflammation. We ask why it’s there in the first place.

We look for the sparks:
✔️ Gut imbalances
✔️ Food sensitivities
✔️ Hidden infections
✔️ Chronic stress
✔️ Environmental toxins

When you remove the triggers and support the body’s natural repair systems, inflammation doesn’t have to control your health story.

It’s not about “putting out fires.”
It’s about creating a body that doesn’t keep lighting them.

The FDA just dropped a bombshell: hormone therapy for menopause will no longer carry a black box warning for breast canc...
11/11/2025

The FDA just dropped a bombshell: hormone therapy for menopause will no longer carry a black box warning for breast cancer, heart attack, or stroke.

For years, women were told hormones were dangerous—only to find out the science behind that fear was outdated and misapplied.

Functional medicine has always known that hormones are powerful messengers, not villains. The key is balance, not suppression.

So while mainstream medicine celebrates this “new” discovery, let’s not forget: women’s voices were dismissed for decades.

The truth? Healing is personalized. Hormones are one part of the whole picture alongside nutrition, gut health, detoxification, stress, and metabolic function.

This isn’t just about menopause. It’s about rewriting the narrative on women’s health.

The latest news cycle says melatonin users are more likely to develop heart failure.That makes for a great headline, but...
11/10/2025

The latest news cycle says melatonin users are more likely to develop heart failure.
That makes for a great headline, but not great science.

Melatonin isn’t the cause. It’s a clue.
People with insomnia and stress-related sleep issues often turn to supplements for relief, and those same imbalances raise cardiac risk on their own.

In functional medicine, we don’t stop at the symptom. We ask why.
Why is melatonin production low?
Why is the circadian rhythm off?
Why is the stress response overactive?

Long-term melatonin use isn’t something to fear, but it is something to investigate.
Address the underlying physiology not the supplement.

Unfortunately, we have to cancel our Navigating the Terrain webinar this evening.But make sure you join us next Monday n...
11/10/2025

Unfortunately, we have to cancel our Navigating the Terrain webinar this evening.

But make sure you join us next Monday night at 6 p.m. CT for our What You're Not Hearing webinar series where we will be discussing PCOS.

Sign up to attend and receive the recording: https://bit.ly/45XxR5r

This series goes deeper into what’s overlooked, rarely explained, and essential to understanding real care. Join us on the third Monday of each month as we talk about what you’re not hearing — but should be. Sign up once to be registered for all upcoming sessions. You’ll receive reminders, r...

Here’s what we now understand:1. Blood sugar drives inflammationRefined carbs and added sugars spike insulin, which over...
11/07/2025

Here’s what we now understand:

1. Blood sugar drives inflammation
Refined carbs and added sugars spike insulin, which over time increases inflammation, stiffens arteries, and disrupts endothelial function (how your blood vessels relax and contract). Chronic insulin spikes also raise blood pressure indirectly—by activating the sympathetic nervous system and the kidneys’ sodium retention pathways.

2. Salt is essential
Sodium is a critical electrolyte for nerve conduction, muscle contraction, and hydration. The problem isn’t salt itself, but the type and context:
→ Processed foods = high sodium + high sugar + zero potassium = trouble.
→ Whole foods + quality salt (like sea salt or Himalayan) + adequate hydration = balance.

3. Metabolic dysfunction starts in the pantry, not the salt shaker.
When 70% of the sodium people eat comes from processed foods, it’s not the pinch of salt on your eggs that’s the issue—it’s the packaged, sugar-laden, refined-carb diet driving chronic inflammation, insulin resistance, and vascular stress.

Instead of isolating single nutrients as “good” or “bad,” look at the whole system. Minerals, glucose regulation, gut health, and inflammation all connect. The goal isn’t to cut salt, it’s to rebalance metabolism.

So before you fear your electrolytes, check your sugar intake.

You don’t have to do everything perfectly to move toward healing.You just have to keep choosing small, sustainable steps...
11/06/2025

You don’t have to do everything perfectly to move toward healing.
You just have to keep choosing small, sustainable steps that support your body.

Because wellness isn’t built through extremes...it’s built through consistency, grace, and the quiet moments you choose to keep going.

Progress looks different every day. What matters is that you stay connected to your intention, even when the pace slows.

Little choices, repeated often, become lasting change.

The connection between hormones and brain health runs deeper than most realize.A new meta-analysis shows that estrogen a...
11/05/2025

The connection between hormones and brain health runs deeper than most realize.
A new meta-analysis shows that estrogen and progesterone—when started at the right time—can protect the brain from dementia and cognitive decline.

We look at the whole picture: genetics, timing, hormone type, and delivery method. Because optimal health isn’t about suppressing symptoms. It’s about supporting physiology.

Let’s start talking about hormone therapy as brain therapy.

While you’re dreaming, your body is hustling.Each organ clocks in for the night shift...detoxing, repairing, and restori...
11/04/2025

While you’re dreaming, your body is hustling.

Each organ clocks in for the night shift...detoxing, repairing, and restoring you from the inside out.

Your brain clears out toxins
Your heart takes a rest
Your muscles rebuild
Your immune system powers up

Sleep isn’t lazy—it’s biological maintenance mode.

A New England Journal of Medicine study just found microplastics and nanoplastics lodged inside arterial plaque, and tho...
11/03/2025

A New England Journal of Medicine study just found microplastics and nanoplastics lodged inside arterial plaque, and those patients were 4.5x more likely to have a heart attack, stroke, or die within three years.

From a functional medicine lens, this is more than a cardiovascular story...it’s an environmental inflammation story.

The body sees these particles as foreign invaders, sparking immune activation and oxidative stress—the very processes that drive atherosclerosis, autoimmunity, and chronic disease.

It’s time we stop thinking of “environmental” toxins as out there and start recognizing they’re in here.

Too many Halloween treats? No worries.Hydrate, eat some protein + veggies, and take a walk—your body’s got this.
10/31/2025

Too many Halloween treats? No worries.
Hydrate, eat some protein + veggies, and take a walk—your body’s got this.

Every fall, we “gain” an hour, but our circadian rhythm doesn’t always agree. Even this small shift can disrupt sleep pa...
10/30/2025

Every fall, we “gain” an hour, but our circadian rhythm doesn’t always agree. Even this small shift can disrupt sleep patterns, hormone balance, mood, and metabolism. In functional medicine, we look beyond the clock to how your biological timing system — your circadian rhythm — interacts with light, cortisol, melatonin, and even your gut microbiome.

Here’s what happens:
Your suprachiasmatic nucleus (SCN) — the brain’s master clock — synchronizes with light exposure. When time changes abruptly, your cortisol rhythm (which should peak in the morning and dip at night) can get out of sync, leaving you groggy in the morning or wired at night.

Poor sleep quality or inconsistent light cues can also affect blood sugar, mood, and immune function.

If you’re feeling “off” after the time change, here’s how to support your body’s natural rhythm:

Morning Light Therapy – Get 10–15 minutes of natural sunlight within an hour of waking. This helps reset your internal clock and boosts serotonin.

Consistent Wake Time – Even on weekends! A stable sleep-wake cycle helps your cortisol and melatonin stay balanced.

Early Evening Wind-Down – Dim the lights, avoid screens, and consider magnesium glycinate or L-theanine if your nervous system feels “wired.”

Support Your Cortisol Curve – Adaptogens like rhodiola or ashwagandha can gently regulate stress hormones (check with your practitioner before adding new supplements).

Optimize Sleep Nutrients – Think magnesium, B6, and GABA-rich foods like avocado, almonds, and leafy greens.

Gentle Movement – Morning walks or yoga help recalibrate both your nervous system and circadian rhythm.

Your body thrives on rhythm, not chaos. Honor it by slowing down, nourishing deeply, and letting light guide your timing.

Estrogen isn’t bad — but how your body metabolizes it matters.DIM helps shift estrogen toward the protective 2-OH pathwa...
10/30/2025

Estrogen isn’t bad — but how your body metabolizes it matters.
DIM helps shift estrogen toward the protective 2-OH pathway—the one linked with better hormone balance and fewer symptoms.

Think of it as your body’s traffic cop keeping estrogen on the right track.
It’s simple biochemistry, not hype.

Address

640 Cepi Drive
Chesterfield, MO
63005

Opening Hours

Monday 8am - 5pm
Tuesday 8am - 5pm
Wednesday 8am - 5pm
Thursday 8am - 5pm
Friday 8am - 5pm

Website

https://www.jamesclinic.com/, https://shop.jamesclinic.com/

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