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Oral Cancer Institute

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Chicago, IL
Oral Cancer Institute

We at the Oral Cancer Institute pride our-selves in providing world-class care.

04/03/2026

Histopathological Variants of Ameloblastoma

Ameloblastomas are classified into several histopathological subtypes, including follicular, acanthomatous, granular, basal, desmoplastic, and plexiform. Among these, desmoplastic ameloblastoma is unique due to its distinct histomorphology, characterized by extensive stromal collagenization or desmoplasia. This variant frequently presents as a mixed radiolucent-radioopaque lesion on radiographs, often affecting the anterior maxilla.

Ameloblastoma treatment can be enhanced with virtual surgical planning, enabling precise resection and optimal reconstruction to restore form and function.

📞 For expert consultation, contact OCI at ☎️ 773-245-5253 or visit our website.

https://oralcancer.com/ameloblastoma/

04/01/2026

Combining bone grafting with PRP (Platelet-Rich Plasma) therapy is a cutting-edge approach in benign jaw tumor reconstruction.

PRP therapy utilizes the patient's blood to concentrate growth factors, significantly enhancing the body's natural healing processes, accelerating recovery, and promoting tissue regeneration. This is considered to be a form of tissue engineering.
The Oral Cancer Institute is committed to providing our patients with the latest and most effective treatments.

Call 📞773-245-5253 to schedule a consultation.

https://oralcancer.com/bone-grafting/

03/30/2026

🦠 HPV-Associated OPSCC: Key Facts

HPV-associated oropharyngeal squamous cell carcinoma (OPSCC) arises from persistent HPV infection in the oral mucosa, which can progress to invasive cancer over a decade if not cleared. The overwhelming majority of infections are cleared and do not lead to any issues. However, a small minority may persist and lead to malignancy.

Histopathology: In HPV-positive OPSCC, tumors typically develop in any of the sites in the throat or oropharynx. For the the tonsillar cancers specifically that arise deep in the tonsillar crypt epithelium, making them difficult to detect through visual inspection or superficial biopsy. Enlarged neck lymph nodes can often be the first present sign in some of these cases.

For more details, contact OCI at ☎️ 773-245-5253 or visit our website.

https://oralcancer.com/

03/27/2026

Let's dive deeper into the major salivary glands, which are the largest and most important and produce most of the saliva in your mouth.

There are three pairs of major salivary glands:

✳️Parotid Glands: The most prominent salivary glands, located just in front of the ears. Saliva from these glands is secreted into the mouth through a duct near your upper second molar.

✳️Submandibular Glands: About the size of a walnut, these glands are located below the jaw. Saliva produced here is secreted into the mouth from under the tongue.

✳️Sublingual Glands: These are the smallest of the major salivary glands under the tongue. They produce saliva that is secreted directly into the mouth.

Call OCI today for a consultation 📞773-245-5253.

https://oralcancer.com/salivary-glands/

03/23/2026

Key Features of HPV-Associated Oropharyngeal Squamous Cell Carcinoma (HPV-OPSCC)

🔹Location:
It primarily affects the tonsillar crypts and the base of the tongue, which is rich in lymphoid tissue.

🔹Symptoms:
Persistent sore throat
Difficulty swallowing
Voice changes
Ear pain
Enlarged cervical lymph nodes

🔹 Presentation:
It often presents at later stages (e.g., nodal metastasis) but typically has a better prognosis than to***co-related oropharyngeal cancers due to its molecular behavior and treatment responsiveness.

☎️ For expert evaluation, contact OCI at 773-245-5253 or visit our website.

https://oralcancer.com/oro-pharyngeal-cancer/

03/20/2026

Understanding the early symptoms of Oral cancer is vital to prompt diagnosis and treatment. Here are the top 5 warning signs you should be aware of:

1. A persistent lump in the neck.
2. Oral Lesion/ ulcer that does not heal for 2 weeks.
3. Unexplained Numbness in the lips
4. Experiencing a horse voice.
5. Feeling pain when swallowing.

🌟 Don't wait if you notice these signs. Schedule a visit at 773-245-5253 with OCI for expert evaluation and care.

https://oralcancer.com/oral-cancer/

03/18/2026

Post-Surgical Reconstruction in Oral Cancer Treatment

Reconstruction after oral cancer surgery is vital to restoring both functionality and aesthetics. Surgeons often use grafts and flaps to rebuild areas affected by extensive resections. One advanced technique, microvascular free flap reconstruction, is commonly utilized to reconstruct the jaw and oral cavity, significantly improving patient outcomes and quality of life.

This approach allows for precise restoration and long-term stability, helping patients recover physically and functionally.

☎️ For more information on advanced reconstructive techniques, call us at 773-245-5253 or visit our website.

https://oralcancer.com/reconstruction/

03/16/2026

The "Fibula Jaw in a Day" procedure is a revolutionary surgical technique that reconstructs the jaw using the fibula bone from the leg. This allows jaw reconstruction and dental implants in one day, significantly reducing treatment time. This innovative method integrates advanced imaging and 3D printing technology to create precise surgical guides, ensuring optimal fit and function for patients.
This approach not only enhances recovery but also improves overall patient outcomes.
For more information, call 📞773-245-5253 or visit our website.

https://oralcancer.com/fibula-jaw-in-a-day/

03/13/2026

Minimally invasive surgery:

Our surgeons at the OCI are experts in minimally invasive surgery. Due to their medical, surgical, and dental backgrounds, they are often able to perform large cancer operations while minimizing external incisions and scars.

Have you or one of your patients been diagnosed with oral cancer? Call OCI for any inquiries you might have. We're here to help!📞 773-245-5253

https://oralcancer.com/oral-cancer/

03/09/2026

💊 Medication-Related Osteonecrosis of the Jaw (MRONJ): Clinical Insights

MRONJ arises primarily in patients receiving bisphosphonates, denosumab, or antiangiogenic therapies. It often follows minor trauma or dental surgery and is marked by exposed necrotic bone, non-healing wounds, and secondary infections.

Key considerations:

Risk factors: Cancer treatments, prolonged bisphosphonate use, corticosteroids.
Management: Conservative therapies include oral rinses and antibiotics; advanced cases may necessitate surgical debridement or resection.
Prevention involves careful assessment before dental interventions and close monitoring of high-risk patients.

📞 For MRONJ management protocols, contact OCI at 773-245-5253 or visit:
👉 https://oralcancer.com/medication-related-osteonecrosis-mronj/

03/06/2026

Understanding the Pathogenesis of HPV-Associated Oropharyngeal Squamous Cell Carcinoma (HPV-OPSCC)

HPV-OPSCC arises from a unique mechanism involving the integration of HPV DNA into the host cell's genome. The viral oncoproteins E6 and E7 disrupt key tumor-suppressor genes:

p53: E6 promotes the degradation of this critical gene, compromising cell cycle regulation and DNA repair.
RB1: E7 inhibits this gene, leading to uncontrolled cell division.

This disruption creates an environment for unchecked cellular proliferation, eventually resulting in malignancy. Unlike traditional oropharyngeal cancers caused by to***co or alcohol, HPV-OPSCC develops in younger, non-smoking individuals and presents with a distinct molecular profile.

Understanding this pathogenesis underscores the importance of HPV vaccination and early intervention in preventing HPV-related malignancies.

☎️ For expert consultation on HPV-OPSCC, call us at 773-245-5253 or visit our website.

https://oralcancer.com/oro-pharyngeal-cancer/

03/04/2026

📣 Meet Dr. James Murphy, one of our esteemed Oral and Maxillofacial Surgeons at the Oral Cancer Institute!

Dr. Murphy brings a wealth of experience and expertise in treating a wide range of oral and maxillofacial conditions. Committed to patient care and surgical excellence, he specializes in oral cancer treatment, complex facial trauma reconstruction, and dental implant surgery.

Dr. Murphy completed his surgical training at top institutions and has since dedicated his career to advancing the field of oral and maxillofacial surgery. He is known for his compassionate approach, ensuring that each patient receives personalized care and attention.

We are proud to have Dr. Murphy on our team, delivering world-class care to our community!

📞 Schedule a consultation with Dr. Murphy today: ☎️ 773-245-5253

https://oralcancer.com/dr-james-murphy/

Address

811 W Wellington Street
Chicago, IL
60657

Opening Hours

Monday	8am - 5pm
Tuesday	8am - 5pm
Wednesday	8am - 5pm
Thursday	8am - 5pm
Friday	8am - 5pm

Telephone

+17732455253

Website

http://www.OralCancer.com/, http://www.OralCancer.com/

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