JAMA Cardiology

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In the ARTESiA randomized trial subanalysis, apixaban increased the risk of major gastrointestinal bleeding compared to ...
12/20/2025

In the ARTESiA randomized trial subanalysis, apixaban increased the risk of major gastrointestinal bleeding compared to aspirin in patients with subclinical atrial fibrillation (SCAF), but rates of fatal and intracranial bleeding were similar between groups.

Most bleeding events were nonemergencies, driven by hemoglobin decrease, and were more likely in those using NSAIDs, with cancer, randomized to apixaban, or older age.

https://ja.ma/3L4AlXr

Among patients with , elevated BMI, and 1 or more additional cardiometabolic risk factors, aggressive risk factor manag...
12/19/2025

Among patients with , elevated BMI, and 1 or more additional cardiometabolic risk factors, aggressive risk factor management reduced arrhythmia recurrence over the 12-month period after catheter ablation. https://ja.ma/3YAZhsN

Changing from high-sensitivity cardiac troponin I to T assay doubled myocardial injury detection and admissions, without...
12/18/2025

Changing from high-sensitivity cardiac troponin I to T assay doubled myocardial injury detection and admissions, without improving 1-year cardiovascular outcomes in suspected . https://ja.ma/3KP1OMT

Women with preeclampsia, other hypertensive disorders, large for gestational age, preterm delivery, or gestational diabe...
12/18/2025

Women with preeclampsia, other hypertensive disorders, large for gestational age, preterm delivery, or gestational diabetes had an increased long-term risk of developing atrial fibrillation, supporting early prevention and ongoing clinical follow-up.

https://ja.ma/4pRIldO

is the most prevalent valvular disorder in the US and is associated with adverse outcomes if left untreated. This narr...
12/17/2025

is the most prevalent valvular disorder in the US and is associated with adverse outcomes if left untreated.

This narrative review describes current guidelines for intervention in severe primary mitral regurgitation and explores an approach that incorporates additional injury assessment, novel imaging markers, and biomarkers to optimize surgical timing.

https://ja.ma/3KVplvA

Intensive lipid-lowering therapy and lower on-treatment LDL-C were associated with less neoatherosclerosis and reduced l...
12/17/2025

Intensive lipid-lowering therapy and lower on-treatment LDL-C were associated with less neoatherosclerosis and reduced late stent failure risk after for STEMI.

https://ja.ma/44xA06f

Editorial: Nonoptimal temperatures—both extreme heat and cold—pose major risks for cardiovascular events and mortality w...
12/16/2025

Editorial: Nonoptimal temperatures—both extreme heat and cold—pose major risks for cardiovascular events and mortality worldwide, with climate change intensifying temperature extremes and their health impacts. https://ja.ma/49exaWn

Short-term exposure to both low and high temperatures was associated with increased all-cause and CVD mortality risk amo...
12/16/2025

Short-term exposure to both low and high temperatures was associated with increased all-cause and CVD mortality risk among patients with heart failure in Sweden. https://ja.ma/4ap05IB

Papillary muscle scarring detected by dark blood MRI in dilated cardiomyopathy patients was independently associated wit...
12/15/2025

Papillary muscle scarring detected by dark blood MRI in dilated cardiomyopathy patients was independently associated with increased cardiac death, heart failure events, and arrhythmia, offering additional prognostic value. https://ja.ma/4j6LvYn

💬 Editorial: Clonal hematopoiesis of indeterminate potential (CHIP) is emerging as a prevalent age-related cardiovascula...
12/14/2025

💬 Editorial: Clonal hematopoiesis of indeterminate potential (CHIP) is emerging as a prevalent age-related cardiovascular risk factor, and new analysis from the ASPREE trial suggests CHIP is linked to increased bleeding risk but not major cardiovascular events in healthy older adults.

https://ja.ma/3YuMOqo

In older adults, CHIP was not linked to higher cardiovascular risk but was associated with increased clinically signific...
12/14/2025

In older adults, CHIP was not linked to higher cardiovascular risk but was associated with increased clinically significant bleeding, and aspirin’s effects on CVD and bleeding did not differ based on CHIP presence. https://ja.ma/4iTX991

In 152 male marathon runners, right ventricular ejection fraction declined transiently after a marathon but recovered wi...
12/13/2025

In 152 male marathon runners, right ventricular ejection fraction declined transiently after a marathon but recovered within 3 days and remained stable at 10-year follow-up. https://ja.ma/4qayAaj

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