03/11/2026
In this episode of HeadWise, host Lindsay Weitzel, PhD, is joined by headache medicine specialist Fred Cohen, MD, director of Headache Intervention in New York City and assistant professor at the Icahn School of Medicine at Mount Sinai, to discuss why headache attacks commonly occur during viral illnesses like the flu, COVID, and other infections.
They explore how inflammation and immune responses during illness can trigger headache attacks, why some people experience migraine attacks when they are sick, and why headache attacks can sometimes continue even after the infection has resolved. They offer guidance on recognizing different types of headache attacks and understanding when to seek medical evaluation.
Topics covered include:
- Why headaches commonly occur during viral illnesses
- The role of inflammation and immune response in triggering headache attacks
- How viral infections can trigger migraine attacks in people living with migraine
- The difference between sinus headache, migraine, and viral headache
- What post-infectious headache is and why it can persist after illness
- When to use migraine medication versus over-the-counter treatments
- When to consult a primary care provider, ENT, or headache specialist
- Why recovery timelines can vary from person to person
This episode offers practical insights for people living with migraine disease and headache disorders, as well as those who may develop headache attacks for the first time during or after viral illness.