Exercise Neuroscience Research Laboratory

Exercise Neuroscience Research Laboratory Our mission is to advance research in neurological conditions to support those that are affected.

Dedicated to the study of exercise and its life changing benefits in persons with multiple sclerosis!

Walk MS season is approaching, and we are ready for it! The Exercise Neuroscience Research Laboratory will be attending ...
04/02/2026

Walk MS season is approaching, and we are ready for it! The Exercise Neuroscience Research Laboratory will be attending Walk MS: Chicago on Sunday, April 26, and we would love to see YOU there!

Want to join our Walk MS team? Visit https://events.nationalmssociety.org/teams/96994

04/01/2026

Prof. Rob Motl recently discussed with Erin Stevenson how she incorporates fitness and wellness into her journey with multiple sclerosis.

Watch the full video on our YouTube channel! https://youtu.be/800o-ndfhAc

Past evidence has established many benefits related to improved cardiorespiratory fitness in people with multiple sclero...
03/27/2026

Past evidence has established many benefits related to improved cardiorespiratory fitness in people with multiple sclerosis. However, the research among those with advanced MS remains limited.

Researchers conducted a study to characterize and compare the cardiorespiratory response to three types of exercise in people with advanced MS. These findings will help guide evidence-based exercise prescription for those with advanced MS.

Read more in Multiple Sclerosis and Related Disorders: https://doi.org/10.1016/j.msard.2026.107065

Thomas Edwards, Arthur Chaves, Zain Awadia, Julia Ludgate, Lisa Walker, Jennifer Reed, Lara Pilutti

Come support AIMS at their bowling fundraiser! Assisting Individuals with Multiple Sclerosis (AIMS) is dedicated to prov...
03/26/2026

Come support AIMS at their bowling fundraiser! Assisting Individuals with Multiple Sclerosis (AIMS) is dedicated to providing direct support to individuals affected by MS, raising public awareness and understanding of MS.

Visit https://www.helpaims.org/events for more information.

What if your smartphone, smartwatch, or fitness tracker could provide clinically meaningful data metrics to researchers ...
03/25/2026

What if your smartphone, smartwatch, or fitness tracker could provide clinically meaningful data metrics to researchers and clinicians?

In this review, researchers examine the use of wearable technologies in monitoring and supporting mobility in people with multiple sclerosis and offer rationale for integrating Mobile Health into clinical practice to better inform mobility interventions for people with MS.

Read more in Exercise and Sport Sciences Reviews: https://doi.org/10.1249/jes.0000000000000382

Jeffer Sasaki, Emerson Sebastião, Robert Motl

Multiple sclerosis is highly prevalent among older adults, and the combined effects of MS progression and aging may cont...
03/17/2026

Multiple sclerosis is highly prevalent among older adults, and the combined effects of MS progression and aging may contribute to worsening cognition, symptoms, and quality of life.

This phase-Ib, randomized controlled trial is the first to report preliminary efficacy of an aerobic and resistance exercise training program guided by current exercise guidelines for MS among older adults.

Thank you to the Healthy Aging through LifesTyle in MS Research Center (created by the National MS Society) for supporting this study!

Read more in Multiple Sclerosis and Related Disorders: https://doi.org/10.1016/j.msard.2026.107105

Peixuan Zheng, Sydney R. DeJonge, Noah G. Dubose, Ariel Kidwell-Chandler, Trevor B. Martin, Trinh L.T. Huynh, Robert W. Motl

Researchers at Purdue University are working to evaluate the association that certain behaviors and attitudes have with ...
03/16/2026

Researchers at Purdue University are working to evaluate the association that certain behaviors and attitudes have with physical activity, as well as how fatigue can impact these associations in people with multiple sclerosis. Please see the flyer for more information on how to participate!

Thank you to  for welcoming us to speak with attendees and lead a movement session! The event was filled with so much jo...
03/16/2026

Thank you to for welcoming us to speak with attendees and lead a movement session! The event was filled with so much joy and ease which is what MS-ing Around is all about!

03/04/2026

The ENRL is happy to congratulate Dr. Petra Šilić! She successfully defended her dissertation, “Physical Activity and Exercise in People with Multiple Sclerosis and Generalized Anxiety Disorder.” We are so excited to see her continue to do great things!

This study funded by the Danish MS Society hypothesized that an outdoor walking exercise program would substantially imp...
03/02/2026

This study funded by the Danish MS Society hypothesized that an outdoor walking exercise program would substantially improve walking capacity, mental well-being, and quality of life in persons with multiple sclerosis. The results suggest that this therapy can serve as an example of an exercise concept to improve and/or preserve walking capacity and mental wellbeing in MS.

Read more in Annals of Physical and Rehabilitation Medicine: https://doi.org/10.1016/j.rehab.2025.101985

Lars Hvid, Josephine Steenberg, Freja Roy, Lasse Skovgaard

Physical activity is important for people with multiple sclerosis, but how can we practically identify who is at risk fo...
02/27/2026

Physical activity is important for people with multiple sclerosis, but how can we practically identify who is at risk for low physical activity levels?

"This study aimed to develop a clinically useful approach combining patient-reported outcomes and objective measures to determine whether PwMS meet step count goals."

Read more in Neurorehabilitation and Neural Repair: https://doi.org/10.1177/15459683251412279

Michael VanNostrand, Patrick Monaghan, Taylor Takla, Nora Fritz

Drs. Lexi Huynh and Robert Motl published a pilot RCT demonstrating that a COM‑B-based physical activity intervention ca...
02/24/2026

Drs. Lexi Huynh and Robert Motl published a pilot RCT demonstrating that a COM‑B-based physical activity intervention can meaningfully boost physical activity levels and enhance mental health in people newly diagnosed with multiple sclerosis. This informs future research by displaying how targeted behavior‑change strategies can make a real difference during a critical period post‑diagnosis.

Read more in Multiple Sclerosis and Related Disorders: https://doi.org/10.1016/j.msard.2026.107031

Address

1919 W Taylor Street, AHSB 545
Chicago, IL
60612

Opening Hours

Monday 8am - 5pm
Tuesday 8am - 5pm
Wednesday 8am - 4pm
Thursday 8am - 5pm
Friday 8am - 5pm

Telephone

+13124134967

Website

https://linktr.ee/enrluic

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