JAMA

11/20/2025

How can AI systems reason safely in the open world of medicine?

JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, talks with Eric Horvitz, MD, PhD, Chief Scientific Officer at Microsoft, about the future of AI in 5 years to 100 years, from neurons to the nebulous, and how we can guide AI to be copilots while maintaining integrity and safety in the clinical arena.

🎧 Listen now: https://ja.ma/3X7z58s

11/20/2025

is a common disease among older adults that weakens bones and increases the likelihood of fractures.

Worldwide, 1 in 3 women and 1 in 5 men older than 50 years have a bone fracture due to osteoporosis during their lifetime.

This JAMA Patient Page describes osteoporosis risk factors, symptoms, screening, diagnosis, and treatment. https://ja.ma/481nFIs

11/20/2025

💬 Editor's Note: How can systems reason safely in the open world of medicine?

JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, talks with Eric Horvitz, MD, PhD, Chief Scientific Officer at Microsoft, about the future of AI in 5 years to 100 years, from neurons to the nebulous, and how we can guide AI to be copilots while maintaining integrity and safety in the clinical arena.

https://ja.ma/3X2yW6i

11/20/2025

We are accepting applications for the 2026-2027 Morris Fishbein Fellowship in Medical Editing. Fellows will:

✅ Review and prepare research manuscripts for publication
✅ Learn about medical illustration
✅ Record podcasts
✅ Provide MD review for social media
✅ Write for JAMA Patient Pages

For more information and to download the application, visit: https://ja.ma/3KDPWwv

11/20/2025

Editorial: "Remembering Drummond Rennie—Champion of Integrity in Science and Scientific Publication."

Drummond Rennie, physician, scientist, editor, climber, tireless promoter of integrity and transparency in science, and mentor to many, died on September 12, 2025, at the age of 89.

11/20/2025

Among patients undergoing transcatheter atrial septal defect closure, a bioresorbable occluder was noninferior to a metallic occluder for 6-month and 2-year closure success and device safety, with near-complete device degradation at 2 years.

https://ja.ma/4p1fHGk

11/20/2025

How can transparency and communication help build trust in -driven health care?

Listen to JAMA+ AI Editor-in-Chief Roy Perlis, MD, MSc, and Associate Editor Yulin Hswen, ScD, MPH, discuss this and more in this special anniversary episode of JAMA+ AI.

🎧 Listen to the full discussion: https://ja.ma/49v47P0

JAMA+ AI is a trusted channel for all AI-related content from the JAMA Network, curated in one place and guided by leading experts in the field.

🔗 Visit JAMA+ AI and learn more: https://ja.ma/48igsoF

11/19/2025

Perinatal affects about 1 in 7 individuals, with symptoms including impaired attachment and risk of su***de. The American College of Obstetricians and Gynecologists (ACOG) recommends universal screening during and care, supported by evidence from US cohort studies and alignment with US Preventive Services Task Force guidelines.

💡 This JAMA Insights discusses the most effective pharmacological treatments for individuals experiencing perinatal depression.

https://ja.ma/3XyFfP8

11/19/2025

💬 Editorial: screening with low-dose CT is recommended for high-risk adults and can substantially reduce mortality. However, in 2024, only 19% of eligible US adults underwent screening, preventing 15 000 deaths—far below the potential impact if eligibility and uptake expanded.

https://ja.ma/3XGnQE4

11/19/2025

Annual lung cancer screening (LCS) reduces lung cancer mortality and is recommended by the US Preventive Services Task Force.

In 2024, only 19% of eligible individuals in the US reported up-to-date screening, preventing an estimated 15 000 deaths. Expanding LCS to all eligible individuals could triple deaths prevented and life-years gained.

https://ja.ma/3X3WjMM

11/19/2025

promises to profoundly change health care, from clinical practice, to training, to research.

JAMA+ AI Editor in Chief Roy Perlis, MD, MSc, highlights 5 key things to consider as these technologies develop.

JAMA+ AI offers research and articles with strategies for evaluating health effects, regulating tools, and ensuring responsible use.

🔗 Visit JAMA+ AI and sign up for the newsletter: https://ja.ma/3X4Gbe2

11/19/2025

After mechanical thrombectomy for acute LVO stroke, intra-arterial alteplase increased the rate of excellent 90-day functional outcomes without raising symptomatic intracranial hemorrhage.

https://ja.ma/4i3YRE6