03/23/2026
Excited to share another RIDE CINCINNATI grant recipient, the University of Cincinnati! Check out how this team of researchers are working to create safer, more personalized treatments for children with brain tumors.
Did you know that the Cincinnati Cancer Advisors are powered by the Cincinnati Cancer Foundation, Inc.? Our Foundation also support education and research funding, through our partnership with Ride Cincinnati. 🚲🔬
Learn more at:
https://ridecincinnati.org/events/502
GRANT RECIPIENT SPOTLIGHT: The University of Cincinnati: Integrating S*x, a Biological Variable in FLASH Radiotherapy, for Pediatric Neuro-Oncology
Brain tumors account for nearly 25% of all pediatric cancer diagnoses. Treatments like radiation help more children survive, but can cause long-term cognitive issues that impact learning and memory.
Newer types of proton-based radiation could potentially help reduce damage to healthy brain tissue, but researchers are still working to fully understand the developing brain and how it reacts to these treatments.
At the University of Cincinnati, preliminary data gathered by a team of researchers showed that female survivors of pediatric brain cancer are potentially more likely to experience cognitive side effects after radiation. Their findings show that female brain tissue may experience more inflammation after treatment.
Their research is focused on understanding those differences and exploring how proton FLASH therapy might reduce brain inflammation and protect developing brains, helping to create safer, more personalized treatments for children with brain tumors.
Research team: Ana Gonzalez-Manteiga, Damir Garcia, Anthony Mascia, Mathieu Sertorio, Marc Oria
