Cincinnati Children's Clinical Research Studies

02/05/2026

We are recruiting children and teens 5 to 16 years old with steatosis of the liver (fatty liver) for a study. This is a study to learn whether soy milk can help improve liver disease in children and teens with MASLD. Pay is up to $300. For more information, contact MASHresearch@cchmc.org or 513-636-8867.

02/04/2026

On , we’re reminded that cancer remains one of the greatest challenges—and why continued research is so important.

At Cincinnati Children’s, our top-ranked Cancer and Blood Diseases Institute combines world-class care with cutting-edge research to give children and families the best chance at a healthy future.

Our researchers are making breakthroughs that matter, from the launch of Engraft Learning Network, which brings together cancer centers, researchers, and families to improve outcomes for children receiving stem cell transplants, to the opening of our Applied Gene and Cell Therapy Center, one of the nation’s most advanced facilities for life-saving treatments.

Every discovery brings us closer to more precise, targeted therapies and better outcomes for kids fighting cancer.

👉 Learn more about our latest cancer research on our science blog: https://scienceblog.cincinnatichildrens.org/area/cancer/

02/02/2026

We are recruiting adults for a research study to determine if a tourniquet training application helps learners identify tourniquet errors and how to correct them. Adults who have not participated in prior tourniquet or medical training may participate. Participants may receive up to $125.

For more information, or to see if you qualify, go to www.redcap.link/stopthebleed or contact suzanne.moody@cchmc.org or 513-636-8639.

01/30/2026

Caregivers of a child or adult with an intellectual or developmental disability are needed for an at-home study. Pay is up to $175. For more information, go to www.redcap.link/futureplan.

01/28/2026

We are recruiting children, teens and young adults 6 to 24 years old diagnosed with an intellectual disability and ADHD or have symptoms of ADHD for a drug trial. Pay is up to $325. For more information, go to www.redcap.link/quillivant or contact Riley Argonis at riley.argonis@cchmc.org or 513-803-5140.

01/21/2026

Great news for families of children living with migraine!

A recent clinical trial led by experts at Cincinnati Children’s showed meaningful benefits from the injectable medication AJOVY. Previously approved for adults, AJOVY is now FDA-approved for children ages 6–17 who weigh at least 99 pounds.

This makes AJOVY the only FDA-approved preventive treatment of its kind for episodic migraine in children and adolescents.

🔗 Learn more on our Science Blog – link in comments.

01/14/2026

Innovative research doesn’t always look conventional! Our researchers are always exploring new ways science can help our patients.

It’s something you might expect to see on a sci-fi TV episode, but the latest advancements in medical breathing support might surprise you…with help from your butt. Enteral ventilation (a.k.a. “butt breathing”) is one of the newest forms of support a Cincinnati Children’s Hospital researcher is studying, and it’s gaining traction.

The process utilizes oxygenated fluids that are inserted into the body through an enema-style approach. The body absorbs the liquid into the bloodstream through the colon, a potentially helpful option for medical situations, like inflamed or damaged airways, where breathing tube placement isn’t possible. https://ow.ly/X8Oe50XVz53

🎨 Blair Kelly

01/13/2026

Caregivers of children and teens 2 to 17 years old with Down syndrome are needed for a research study. In this study, researchers want to create a tool to better measure challenging behaviors in children with Down syndrome. It includes caregiver online surveys, a virtual interview, and structured play sessions for children during in-person visits. Pay is up to $400 for study completion (3 in-person visits and 1 virtual visit).

To see if your child is eligible, go to www.redcap.link/BIDS3 or contact Aine at aine.powell@cchmc.org or dsresearch@cchmc.org or 513-636-3058.

01/09/2026

Advancing food allergy care starts with research—learn more below.

Finding the right care is crucial when your child is diagnosed with a food allergy. That’s why our Cincinnati Children's Clinical Research Studies team is recruiting for a study to see if a specialist infant formula designed for food allergy will be tolerated by infants and children with cow’s milk allergy. We're seeking infants and children 3 months to 12 years old. Approved participants will receive payment. Learn more through the link in the comments.

01/08/2026

We are recruiting Hispanic/Latino teens 13 to 17 years old who are interested in sharing their experiences related to their food environments. This is a study to learn more about food access in Hispanic/Latino teens and identify any unique challenges they may experience in their food environments. Participants may receive up to $275. Possible travel reimbursement may also be provided. For more information, or to see if you qualify, go to www.redcap.link/YIDRA or contact Wendy.DeLaRosa@cchmc.org or 513-516-1111.

01/05/2026

Stories like Sriansh’s highlight why we do what we do—turning hope into reality through groundbreaking research and expert care.

Thanks to an innovative clinical trial at Cincinnati Children's, Sriansh is thriving in unimaginable ways. Through this trial, 16-month-old Sriansh received a one-time gene therapy to treat his rare genetic disorder, AADC deficiency, becoming the youngest child in the world to receive this treatment.

Because of this groundbreaking therapy, Sriansh is now walking, running, and swinging – milestones his family never imagined he’d reach. For more on Sriansh’s : https://bit.ly/4pNtWPK

12/29/2025

Children and teens 8 to 18 years old diagnosed with multiple sclerosis (MS) who do not have dental braces are needed for a study which looks at brain cells associated with inflammation. The study involves an MRI and cognitive testing. Pay is up to $125 for 1 or 2 study visits. For more information or to see if you or your child is eligible, contact Karlee at karlee.migneault@cchmc.org or 513-803-5299.