Reliving Ventures

10/08/2023

Happy Birthday Reliv! Just about ready to get this party started in the California Bay Area.

People are being to arrive… the Reliv Tasting Station is ready… cake and ice cream is on ice… and the Reliv 35th Anniversary video is ready to roll. Let’s go!

07/10/2023

Reduce chronic inflammation with Lunarich. Check it out ==> https://your.Reliv.com/p/lunarich

Hair loss is a common problem that can have many causes, including a lack of nutrients in your diet. If you’re looking for ways to promote healthy hair growth and treat hair loss, you may want to consider adding more anti-inflammatory foods to ...

03/02/2023

New research suggests you can see major health benefits from exercising for half the time typically recommended, with short daily walks or bike rides.

02/23/2023

US News is a recognized leader in college, grad school, hospital, mutual fund, and car rankings. Track elected officials, research health conditions, and find news you can use in politics, business, health, and education.

02/18/2023

Growing older doesn’t mean you have to become old. More info at your.Reliv.com !

02/03/2023

The 75-year-old social media sensation shares how she got off medication and started lifting weights, biking and swimming, and how you can change your life too.

02/11/2022

ArticleViewAbstractPharmacognosy Journal,2021,13,5,1269-1276.DOI:10.5530/pj.2021.13.160Published:September 2021Type:Research ArticleIn Vivo Antimammary Tumor Effects of Soybean Extract with Targeted Lunasin (ET-Lun)Numlil Khaira Rusdi, Erni Hernawati Purwaningsih, Andon Hestiantoro, Berna Elya, and....

11/18/2020

I long ago eliminated dairy (except cheese) from my diet and replaced it with soy milk products. I find they are far more digestible and have a greater range of nutritional benefits.

Publications, articles and videos on soy and breast cancer

I have always been asked how to deal with doctors and healthcare practitioners who prohibit the consumption of soy products and continue to perpetuate the debunked myth that soy increases breast cancer risk.

I have compiled a list of peer-reviewed publications from major journals (Journal of the American Medical Association (JAMA), British Journal of Cancer, Journal of the National Cancer Institute, Journal of Nutrition and American Journal of Clinical Nutrition) that report on the results of the most recent human clinical trials on the effect of soy consumption on breast cancer risk.

I have also included peer-reviewed publications on the effect of the lunasin soy peptide on breast cancer cells and metastasis.

Also on the list are news media articles and videos on the safety of soy and its preventive effects on breast cancer.

A lot of medical and naturopathic doctors are grossly misinformed and uneducated on this topic. If doctors insist that soy consumption is bad because it promotes breast cancer, I suggest to ask them to provide you with any peer-reviewed publications, articles and human clinical results that support their contention and contradict these recent human clinical trials. If they can’t, then they should be told that they are wrong and maybe doing more harm to their patients by perpetuating the myth that soy causes human breast cancer and is bad for breast cancer survivors.

Here are some recent publications, articles and videos debunking the claim of doctors and anti-soy proponents that soy promotes breast cancer.

A. Publications reporting the recent clinical studies on the effect of soy and breast cancer risk:

1. Xiao O. S. et al., Soy food intake and survival. Journal of the American Medical Association (JAMA), 2009. 302(22): p. 2473-2443.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874068/pdf/nihms169338.pdf

2. Wu, A.H., et al., Epidemiology of soy exposures and breast cancer risk. Br J Cancer, 2008. 98(1): p. 9-14.
Link: https://www.nature.com/articles/6604145

3. Trock, B.J., L. Hilakivi-Clarke, and R. Clarke, Meta-analysis of soy intake and breast cancer risk. J Natl Cancer Inst, 2006. 98(7): p. 459-71.
Link: http://jnci.oxfordjournals.org/content/98/7/459.full

4. Here is the review paper on soy and breast cancer with Dr. Helferich as co-author. Dr. Helferich’s paper in early 2000 on mice without ovaries was the basis of anti-soy’s claim that soy phytoestrogens promote tumor growth. He reversed his position on this publication.
Hilakivi-Clarke, L., J.E. Andrade, and W. Helferich, Is soy consumption good or bad for the breast? J Nutr, 2010. 140(12): p. 2326S-2334S.
Link: https://academic.oup.com/jn/article/140/12/2326S/4630743?searchresult=1

5. Nechuta SJ et al., Soy food intake after diagnosis of breast cancer and survival: an in-depth analysis of combined evidence from cohort studies of US and Chinese women. Am J Clin Nutr, 2012 ,96(1):123-132.
https://academic.oup.com/ajcn/article/96/1/123/4571417?searchresult=1

6. Protective effects of soy consumption against breast cancer in North American women.
https://faseb.onlinelibrary.wiley.com/doi/10.1096/fasebj.29.1_supplement.406.5

B. Publications on lunasin and breast cancer

7. Effect of lunasin on breast cancer cells : https://link.springer.com/article/10.1007/s12263-012-0307-5

8. Effect of lunasin on breast cancer metastasis: https://www.spandidos-publications.com/or/36/1/253?fbclid=IwAR0mjlPZe1mVESMjXlhRfjkL6LwFa_kohhvFFsqvADSoQ-QSZvcAWZz1BzA

C. News media articles and videos on the safety of soy for prevention and for breast cancer patients and survivors

9. Dr. Michael Greger (NutritionFacts.org) video on BRCA breast cancer genes and soy
https://nutritionfacts.org/video/brca-breast-cancer-genes-and-soy/?fb_action_ids=10201744705552096&fb_action_types=og.likes&fb_ref=.UnJ-f60rp1w.like&fb_source=other_multiline&action_object_map=%7B%2210201744705552096%22%3A245492572272862%7D&action_type_map=%7B%2210201744705552096%22%3A%22og.likes%22%7D&action_ref_map=%7B%2210201744705552096%22%3A%22.UnJ-f60rp1w.like%22%7D&fbclid=IwAR1TQkzHSrCH8IvsECf_cF18DSha7r_Qqsxqbt-Bvwk04KHdEg7jW6cYAJA

10. Will eating soy increase my risk of breast cancer?
https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/expert-answers/soy-breast-cancer-risk/faq-20120377?fbclid=IwAR2Igrw2LigXXlvTFJOBu0ry3XLqv3ScXhIvdr-Yt7CyzRZQO30bSqLWaJM

11. Soyfoods and cancer
https://www.todaysdietitian.com/newarchives/040113p30.shtml?fbclid=IwAR3IkOrZ2kS3CUJxHYpmxRJjL5zV5BYNWVoIL_875r7CDKNsEbZ60mDv8K8

12. Angelina Jolie doctor’s tips to prevent breast cancer
https://abcnews.go.com/GMA/video/angelina-jolies-doctor-shares-tips-prevent-breast-cancer-50243366?fbclid=IwAR3ZIbmcUyr4rJ52pQG1hmBBeFAqE7pJAl88WJD4yeGm7rA9v5sGQhWYuSc

13. NYTimes article: Really? Eating soy increases the risk of breast cancer?
https://well.blogs.nytimes.com/2012/06/25/really-eating-soy-increases-the-risk-of-breast-cancer/?fbclid=IwAR0VZRX4R3jcXdeRyoHRTs7cMoa0VtCdjwmBCtHcqjUqj7izv6R3Rv4SiMk

08/07/2020

Let food be they medicine!

In this Viewpoint directors of the NIH and NIDDK summarize the agency’s 2020-2030 Strategic Plan for NIH Nutrition Research, a roadmap to establish a science of nutrition as a means to prevent and treat illness and to develop actionable, evidence-based dietary recommendations across cultures and.....

06/19/2020

Publications, articles and videos on soy and breast cancer

I have always been asked how to deal with doctors and healthcare practitioners who prohibit the consumption of soy products and continue to perpetuate the debunked myth that soy increases breast cancer risk.

I have compiled a list of peer-reviewed publications from major journals (Journal of the American Medical Association (JAMA), British Journal of Cancer, Journal of the National Cancer Institute, Journal of Nutrition and American Journal of Clinical Nutrition) that report on the results of the most recent human clinical trials on the effect of soy consumption on breast cancer risk.

I have also included peer-reviewed publications on the effect of the lunasin soy peptide on breast cancer cells and metastasis.

Also on the list are news media articles and videos on the safety of soy and its preventive effects on breast cancer.

A lot of medical and naturopathic doctors are grossly misinformed and uneducated on this topic. If doctors insist that soy consumption is bad because it promotes breast cancer, I suggest to ask them to provide you with any peer-reviewed publications, articles and human clinical results that support their contention and contradict these recent human clinical trials. If they can’t, then they should be told that they are wrong and maybe doing more harm to their patients by perpetuating the myth that soy causes human breast cancer and is bad for breast cancer survivors.

Here are some recent publications, articles and videos debunking the claim of doctors and anti-soy proponents that soy promotes breast cancer.

A. Publications reporting the recent clinical studies on the effect of soy and breast cancer risk:

1. Xiao O. S. et al., Soy food intake and survival. Journal of the American Medical Association (JAMA), 2009. 302(22): p. 2473-2443.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874068/pdf/nihms169338.pdf

2. Wu, A.H., et al., Epidemiology of soy exposures and breast cancer risk. Br J Cancer, 2008. 98(1): p. 9-14.
Link: https://www.nature.com/articles/6604145

3. Trock, B.J., L. Hilakivi-Clarke, and R. Clarke, Meta-analysis of soy intake and breast cancer risk. J Natl Cancer Inst, 2006. 98(7): p. 459-71.
Link: http://jnci.oxfordjournals.org/content/98/7/459.full

4. Here is the review paper on soy and breast cancer with Dr. Helferich as co-author. Dr. Helferich’s paper in early 2000 on mice without ovaries was the basis of anti-soy’s claim that soy phytoestrogens promote tumor growth. He reversed his position on this publication.
Hilakivi-Clarke, L., J.E. Andrade, and W. Helferich, Is soy consumption good or bad for the breast? J Nutr, 2010. 140(12): p. 2326S-2334S.
Link: https://academic.oup.com/jn/article/140/12/2326S/4630743?searchresult=1

5. Nechuta SJ et al., Soy food intake after diagnosis of breast cancer and survival: an in-depth analysis of combined evidence from cohort studies of US and Chinese women. Am J Clin Nutr, 2012 ,96(1):123-132.
https://academic.oup.com/ajcn/article/96/1/123/4571417?searchresult=1

6. Protective effects of soy consumption against breast cancer in North American women.
https://faseb.onlinelibrary.wiley.com/doi/10.1096/fasebj.29.1_supplement.406.5

B. Publications on lunasin and breast cancer

7. Effect of lunasin on breast cancer cells : https://link.springer.com/article/10.1007/s12263-012-0307-5

8. Effect of lunasin on breast cancer metastasis: https://www.spandidos-publications.com/or/36/1/253?fbclid=IwAR0mjlPZe1mVESMjXlhRfjkL6LwFa_kohhvFFsqvADSoQ-QSZvcAWZz1BzA

C. News media articles and videos on the safety of soy for prevention and for breast cancer patients and survivors

9. Dr. Michael Greger (NutritionFacts.org) video on BRCA breast cancer genes and soy
https://nutritionfacts.org/video/brca-breast-cancer-genes-and-soy/?fb_action_ids=10201744705552096&fb_action_types=og.likes&fb_ref=.UnJ-f60rp1w.like&fb_source=other_multiline&action_object_map=%7B%2210201744705552096%22%3A245492572272862%7D&action_type_map=%7B%2210201744705552096%22%3A%22og.likes%22%7D&action_ref_map=%7B%2210201744705552096%22%3A%22.UnJ-f60rp1w.like%22%7D&fbclid=IwAR1TQkzHSrCH8IvsECf_cF18DSha7r_Qqsxqbt-Bvwk04KHdEg7jW6cYAJA

10. Will eating soy increase my risk of breast cancer?
https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/expert-answers/soy-breast-cancer-risk/faq-20120377?fbclid=IwAR2Igrw2LigXXlvTFJOBu0ry3XLqv3ScXhIvdr-Yt7CyzRZQO30bSqLWaJM

11. Soyfoods and cancer
https://www.todaysdietitian.com/newarchives/040113p30.shtml?fbclid=IwAR3IkOrZ2kS3CUJxHYpmxRJjL5zV5BYNWVoIL_875r7CDKNsEbZ60mDv8K8

12. Angelina Jolie doctor’s tips to prevent breast cancer
https://abcnews.go.com/GMA/video/angelina-jolies-doctor-shares-tips-prevent-breast-cancer-50243366?fbclid=IwAR3ZIbmcUyr4rJ52pQG1hmBBeFAqE7pJAl88WJD4yeGm7rA9v5sGQhWYuSc

13. NYTimes article: Really? Eating soy increases the risk of breast cancer?
https://well.blogs.nytimes.com/2012/06/25/really-eating-soy-increases-the-risk-of-breast-cancer/?fbclid=IwAR0VZRX4R3jcXdeRyoHRTs7cMoa0VtCdjwmBCtHcqjUqj7izv6R3Rv4SiMk

06/09/2020

AbstractObjectives. Lunasin is a bioactive peptide originally derived from soy protein which is being marketed as a nutraceutical product for its potential ben

06/04/2020

How Covid-19 evades anti-viral response in human cells

Humans have evolved and developed an elaborate immune system to defend and help the body fight back against viruses, other microscopic pathogens and environmental insults.

To keep up, the ever-evolving viruses found ways to evade human immune defenses by taking advantage of our most vulnerable and most conserved cellular protein targets, the N-terminal tails of histones (packaging material of DNA).

As part of the complex regulation of the immune system, the epigenetic control of immunity genes involved in defending against viral infection is modulated by specific modifications to the histone tails.

Corona viruses like, SARS-CoV-2 (virus causing Covid-19), SARS-CoV-1, BAT CoV and influenza viruses contain small linear peptides in their envelope proteins that mimic the histone H3 tail (see attached image and recent paper from Nature). These viral histone mimics are able to bind and sequester key histone-binding regulators such as BET (bromodomain and extra terminal domain) proteins that are required for the activation of antiviral genes. As a result, corona viruses like SARS-CoV-2 can inhibit expression of anti-viral genes, suppress host immune defenses and proceed with infection.

Put simply, by producing a short peptide that mimics histone H3 tail fragment, SARS-CoV-2 is able to outwit our body’s immune defenses and take over cells to propagate themselves and cause Covid-19 infection.

The viral epigenetic interference on our immune system provides new treatment targets and solutions against corona and influenza virus infection. Besides BET inhibitors, it would also be interesting to determine whether the histone-binding seed peptide, lunasin, can help mitigate infection by neutralizing viral histone mimics.

https://www.nature.com/articles/s41586-020-2286-9_reference.pdf