02/05/2024
Adolescent stress altrrs brain genes, affecting adult behavior
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Adolescent Stress Alters Brain Genes, Affecting Adult Behavior
Researchers discovered that excessive stress during adolescence can significantly alter gene expression in the brain, affecting bioenergy-related genes.
Their findings, published in Translational Psychiatry, highlight how these genetic alterations in adolescent rats lead to behavioral problems and psychiatric disorders in adulthood.
The study focused on the prefrontal cortex, a region highly susceptible to stress, where stressed rats showed diminished expression of genes critical for mitochondrial respiration.
This disruption in cell respiration is linked to anxiety, reduced sociability, and impaired cognitive function, illustrating the profound and lasting impact of adolescent stress on brain function and adult behavior.
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